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  • PD Moderators: Esperighanto | JackARoe | Cheshire_Kat

Tryptamines 4-HO-MET high doses (over 40mg) experiences, please?

Ismene2 said:
What kinda dosage do you take? I used upwards of 100mg so maybe Im more liable to feel the effects of a shit synthesis
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I know ludicrous doses are your thing, but it does bear mentioning that 100mg of any 4-ho-met synth would put most people on the floor, and some larger mammals...

But yes I keep my tryptamine doses relatively low, usually around 25mg.

Fwiw I always feel like I have a really sensitive bladder on the tail end of the trip and have to pee a lot. I've always wondered if that's down to the synth or if it's just me and 4-ho-met.
 
I have had a couple of nausea-free trips on the grey stuff but that was a lot lower dose. I found with 4-aco it was very DMT like at bigger doses - most people compare it to mushrooms but when you push the dosage higher it becomes more and more pure ayahuasca - in fact it had a few unique effects that made me place it above ayahuasca.
 
Ismene2 said:
I have had a couple of nausea-free trips on the grey stuff but that was a lot lower dose. I found with 4-aco it was very DMT like at bigger doses - most people compare it to mushrooms but when you push the dosage higher it becomes more and more pure ayahuasca - in fact it had a few unique effects that made me place it above ayahuasca.
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I've read that about higher doses. There was one time I took 100mg of 4-aco-dmt along with 100mg of 4-ho-met and 200mg of 2cb, and 500mg of mescaline...and, some dmt...

But I don't really remember it , and I haven't dosed like that since.

I haven't managed a DMT breakthrough I could remember either, Dunno if I'm doing it wrong or what.

The main reason I don't want to dose higher with 4-aco-dmt is the shear emotional intensity it hits me with at just 25mg is already overwhelming. Shit is humbling.
 
Shinji Ikari said:
I've read that about higher doses. There was one time I took 100mg of 4-aco-dmt along with 100mg of 4-ho-met and 200mg of 2cb, and 500mg of mescaline...and, some dmt...

But I don't really remember it , and I haven't dosed like that since.

I haven't managed a DMT breakthrough I could remember either, Dunno if I'm doing it wrong or what.

The main reason I don't want to dose higher with 4-aco-dmt is the shear emotional intensity it hits me with at just 25mg is already overwhelming. Shit is humbling.
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It was a godsend when I first discovered it - I had to quit oral DMT cos I just couldnt face the nausea anymore but I've always loved oral DMT so 4aco just blew me away.
 
Shinji Ikari said:
I've read that about higher doses. There was one time I took 100mg of 4-aco-dmt along with 100mg of 4-ho-met and 200mg of 2cb, and 500mg of mescaline...and, some dmt...
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😀

What made you take all those at the same time? Were you just in a let it all hang out mood?
 
Esperighanto said:
I really doubt that these differences are coming down to the synthesis of the compound, do you have any evidence of how something like this could happen? It reminds me of people talking about acid feeling "clean" or not, as if LSD is different from LSD somehow based on vibes or some other goofy shit, and it's always the 65 year old burnout on a jam band lot trying to convince me it has to do with elements of chemical synthesis they just don't understand.
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Regardless of whether or not these differences in experience are due to pharmacological reasons (which very well could be in many cases), one important factor is suggestion. Especially in the case of psychedelics, just believing the substance is impure is likely enough to deteriorate the experience.

This is why psychedelics need to be pure as they can be ideally, and the experimentator should have no doubt about either purity nor identity.

Arguing about the effect of impurities in a controlled, blinded setting may not be fruitful, as proving this could be quite the endeavour.
 
Ismene2 said:
😀

What made you take all those at the same time? Were you just in a let it all hang out mood?
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I was on the tail end of a candyflip which I was already propping up with stims and lots of 2cb, completely immersed in the euphoria and decided that meeting God would be the perfect way to end the day. It was either that or sober up and I didn't want to the party to end.

And then the bitch stood me up.
 
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