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4-AcO-DMT + MDMA: safety?

T

tokki g

Greenlighter
Joined
Jun 24, 2011
Messages
19
Can anyone comment on mixing 4-AcO-DMT + MDMA, and/or 4-AcO-DMT + "ecstasy"? May have the chance to get either MDMA or "e" next week (not sure, so please comment on both bc I know e contains more than just MDMA) and am interested in trying this combo with a good friend.

I have a lot of experience with 4-AcO, taking doses up to 60mg. I usually do 50mg at a time, which is roughly equivalent to 1/4oz of shrooms, and normally mix either the 4-AcO-DMT or shrooms with ~30mg 2c-X (usually 2c-e). This produces a roughly a ++ to +++ trip. It's very hard for me to get to a ++++ because my mind has a strong grasp on reality, it's hard to explain but I just have a natural tolerance to most drugs, including alcohol/weed/benzos/whatever. My friend has taken up to 40mg 4-AcO-DMT and I think that produced a +++/++++ trip for her, I'm guessing ++++ bc she had to take 1mg clonazepam to calm her mind down a bit.
I have little/no experience with MDMA/e. I once smoked a joint with a bit of MDMA sprinkled on it, and light seemed a bit brighter but that was it. I snorted ~120mg MDMA about a year ago, but felt little/no effects. I don't know wtf, so if I get the chance I'm gonna pick up at least 200-300mg for myself this time, or 2-3 e pills. My friend has taken MDMA/e a few times, usually just 1 standard dose/pill and will probably only take the same this time around.

Is this tryptamine + PEA combo safe? I'm betting it's fun as hell, I love the emotional fun ride of 4-AcO and I'm sure MDMA is awesome so I really wanna try this, given that it's safe. If there's a chance of a bad interaction from an e pill + 4-AcO, then I won't try it until I get a chance to get MDMA, assuming that combo is safe.
Thanks.
 
MDMA is Ecstasy

Pills tend to have more adulterations (cuts) than MDMA shards, which are typically (from my experience) an slightly tan/opaque to brown sugar color, to translucent (indicative of higher quality)

try MDMA, or a pill when you get the chance, use pillreports.com to look up a specific pill (the one you get) in your region, or use a test kit to make absolutely sure what you are consuming.
 
I don't think there are any dangerous interactions between these two substances. People have been combining mushrooms with MDMA for years and I don't think I've heard of any good reasons why it's a strictly bad idea.

If you get good shit, though, you probably won't need more than 200mg of MDMA. Chances are the stuff you took that one time was weak, as 120mg snorted would affect most people very strongly.
 
To my knowledge it's a safe combo, but I don't know for sure...
I'm gonna move this over to PD to see if you get some better results.




@PD mods:
Send it back if you don't feel like it belongs over there.
 
It is safe combo, you don't need to high dosing. Try 20mg of 4-aco-dmt and 100mg of MDMA first. Be safe and mix tryptamine with crystal mdma, you really don't know what is in the extacy pill and what's the dose
 
rtg said:
It is safe combo, you don't need to high dosing. Try 20mg of 4-aco-dmt and 100mg of MDMA first. Be safe and mix tryptamine with crystal mdma, you really don't know what is in the extacy pill and what's the dose
Click to expand...

It's a lot easier for people to say "only take crystal MDMA" it's another thing to actually do it.
 
tokki g said:
Can anyone comment on mixing 4-AcO-DMT + MDMA, and/or 4-AcO-DMT + "ecstasy"? May have the chance to get either MDMA or "e" next week (not sure, so please comment on both bc I know e contains more than just MDMA) and am interested in trying this combo with a good friend.

I have a lot of experience with 4-AcO, taking doses up to 60mg. I usually do 50mg at a time, which is roughly equivalent to 1/4oz of shrooms, and normally mix either the 4-AcO-DMT or shrooms with ~30mg 2c-X (usually 2c-e). This produces a roughly a ++ to +++ trip. It's very hard for me to get to a ++++ because my mind has a strong grasp on reality, it's hard to explain but I just have a natural tolerance to most drugs, including alcohol/weed/benzos/whatever. My friend has taken up to 40mg 4-AcO-DMT and I think that produced a +++/++++ trip for her, I'm guessing ++++ bc she had to take 1mg clonazepam to calm her mind down a bit.
I have little/no experience with MDMA/e. I once smoked a joint with a bit of MDMA sprinkled on it, and light seemed a bit brighter but that was it. I snorted ~120mg MDMA about a year ago, but felt little/no effects. I don't know wtf, so if I get the chance I'm gonna pick up at least 200-300mg for myself this time, or 2-3 e pills. My friend has taken MDMA/e a few times, usually just 1 standard dose/pill and will probably only take the same this time around.

Is this tryptamine + PEA combo safe? I'm betting it's fun as hell, I love the emotional fun ride of 4-AcO and I'm sure MDMA is awesome so I really wanna try this, given that it's safe. If there's a chance of a bad interaction from an e pill + 4-AcO, then I won't try it until I get a chance to get MDMA, assuming that combo is safe.
Thanks.
Click to expand...

Tryptamines are generally very safe to combine with other substances. I haven´t tried it my self, but I´m pretty sure that there won´t be any bad reactions from combining 4-aco-dmt and mdma. Of cause, in reality no one can tell you what will happen.

That said, it´s a bad idea to mix a new drug with something else, the first time you try it.

I suggest you try MDMA or Ecstacy tablets, or what ever you can get, by it self the first few times. Then later when you are know what effects it gives, then you can combine with 4-aco-dmt.
 
tokki g said:
(not sure, so please comment on both bc I know e contains more than just MDMA)
Click to expand...

Wrong. you should do your best to avoid buying adulterated products. (Pillreports, test kit, sampling a smaller amount of product before buying more)

netcrusher said:
Bring back the fucking mdma ppl and stop messing with our minds with all the TRYPTAMINES
Click to expand...

......the fuck?
 
Bring back the fucking mdma ppl and stop messing with our minds with all the TRYPTAMINES
Click to expand...

Ahahahaha, wut.
...
Theoretically, 4-aco-dmt should be very similar to either psilocybin or psilocin (indeed, the former two should convert to the latter (4-oh-dmt) very quickly in the human body).

'Hippie Flips' have a long record of use and safety, but for your mental well-being, I would keep the doses of either low.

ebola
 
I've noticed a rather large temperature increase mostly around my forehead but really my whole head and body(didn't have thermometer handy, but I was sweating/had to pour water over my head to cool down and sit in front of a fan/etc). This happened twice with ~180mg methylone and ~30+mg 4-aco-dmt. Not sure, but possibly too much serotonin transmission was going on. Looking at the pharmacology of psilocin it seems to inhibit SERT possibly at highish doses + methylone it builds up too much 5ht activity.

but it perplexed me for sure since I had always heard of mushrooms and mdma working out fine.
 
Last edited:
did quite a bit last week- 25mg of 4aco-dmt on top of an MDMA binge (over 300mg bombed then repeated lines) and it was fine for all five of us concerned. a beautifull mix, much more depth than mdma alone
 
Thanks for all the replies. I'll try to get my hands on some "crystal MDMA" if possible, but either way I'm gonna dose the e first and then dose the 4-AcO if I feel comfortable with it.

I should've immediately realized 4-AcO + MDMA = hippy flipping, but whatever, it's not really the same and 4-AcO is still an RC so it doesn't hurt to ask.

I'm not sure how much I'll take, depends on how it goes with just e alone. All this talk about taking lower doses of each makes sense in theory, but in practice I've always found that not taking a full dose of a substance when mixing always causes less-than-desired results for me. Doesn't seem to hold true for others though, so anyone else thinking about mixing anything I would also suggest going with a lower dose of each.
 
I am normally with you on keeping the doses full when mixing substances - but this is usually restricted to mixing different psychedelics together. It is advisable to start low when combining entactogens like MDMA with psychedelics as the MDMA can really exacerbate any negative body load that you might not even notice otherwise from the psychedelic. 2c-e and MDMA at full doses made me projectile vomit so hard it was disgusting and not at all desirable. Start low, and if you find it lackluster, dose higher next time - but don't risk puking your guts out from impatience.
 
Ah, good to know. Thanks, I'll be careful. I have a cast-iron or some other sort of metal or alloy stomach, I've never thrown up during any of my trips and I just dislike puking so even when I'm drunk it's hard for me to throw up. I also am pretty comfortable with the body load from 4-AcO, it's almost nonexistent for me, but I'll still keep an eye out.

The worst bodyload I ever had was from 2c-e as well, but done IM. Only happened the first time I did IM, then I dunno if my body got used to it or something but it never happened on any of my subsequent 2c-e IM trips (never IMed anything else before/after). I think my body got really angry at me for all the serotonin, my stomach got really growly and I could feel my intestines moving and shit. I ended up having really loose stool for the next 24hrs, and had to go to the bathroom a bunch. I dunno wtf. And the trip was really weak for the dose I took. But, like I said, it's never happened since that first time so I dunno what exactly my body did/went through. Subseuent trips have been stronger and given expected results, so I am really confused as to what happened that first time.
I'm sorta curious to see what will happen if I IM something else, but have not come across anything else worth IMing.
 
DPT, possibly 5-meo-dmt are both IM friendly drugs. Or, that is, may have something to be uniquely gained from that ROA. But YMMV, of course, such statements can only be confirmed or denied through experience for the individual.
 
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