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  • Trip Reports Moderator: Cheshire_Kat

2mg Suboxone + 60mg Oxycodone + 2mg Xanax + 100mg Tramadol - New Experience

80mg

80mg

Bluelighter
Joined
Mar 1, 2010
Messages
722
Location
Strong Island, NY
6AM - I wake up with my typical withdrawls. Being the good little addict I am I knew I was going too get pills sometime that day, so without having too wait a whole day I decide too take a 2mg piece of suboxone so at a maximum of twelve hours. I'm ready too rock and roll.

10AM- The one thing I can't STAND about suboxone is that no matter how big or small the piece; bupenorphine knocks me on my ass! Not in a euphoric stony balogna way; like a sleep all day way. Not cool

1PM- I arise from my nap and SWIM (lol jk) meet up with one of my friends. He gives me a xanax bar.

2PM - I buy 2 roxys. I have a redbull too ocunteract the drowziness and I feel alot better. I find bupenorphine too be way more enjoyable with Alprazolam.

2:15 pm - One of my roxys is sniffed.

2:45 pm - The mixtaure is really really euphoric. The suboxone has given me this heavy body high, the oxycodone gave me more pep and euphoria, and the xanax is just the mellow cherry on the top. I also got some tramadols I keep for rainy days after being kicked out of my suboxone program. I take 2 50mg's

3:40pm - As a 5 year opiate veteran with a fortay (sp?) for heroin, and oxycodone...I can't believe how much the suboxone and tramadol has enhanced this high. It's like every type of opiate high feeling you can imagine mixed into one. Time too smoke a few bowl pacts.

5:30 pm - I finish my last roxy and make a tall vodka cocktail.

Too say the least...for the rest of the evening untill this very present moment (6hours later) I still feel a very strong opiate buzz. I'm not going too lie, I think I may have pushed my luck a little too far this time especially mixing benzos and alchol with the mix; but after a two time overdoser, i have an idea of my limits.

Overall though, if you do ignore my warning and decide too be cool (JK!) it is a really nice experience with a mix Ive never tryed. Two rolled up bills up!
 
Lol suboxone blocks oxy I am sure u felt it since you took this much but it would of been so much better without the sub.
 
Dankycodone said:
Lol suboxone blocks oxy I am sure u felt it since you took this much but it would of been so much better without the sub.
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Yep. Next time dont take the suboxone and you will nod even harder. OC+ a little benzo is a nice combo though
 
i may be wrong, but isn't it supposed to be really damaging for your opiate receptors to mix "real" opiates with suboxone? isn't suboxone subutex and naltrexone combined which blocks the receptors preventing you from getting high? This can't be beneficial lol.
 
Sounds like a good time. I wish I had opiates :(

And I thought the subs don't completely block other opiates unless it gets to a certain dosage. Maybe I'm thinking of methadone. Damnit I can't remember.
 
ColinGibs said:
i may be wrong, but isn't it supposed to be really damaging for your opiate receptors to mix "real" opiates with suboxone? isn't suboxone subutex and naltrexone combined which blocks the receptors preventing you from getting high? This can't be beneficial lol.
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You are wrong. Mixing the two will not "damage" your receptors.

It's the buprenorphine, NOT NALTREXONE, that binds to the receptors in your brain and blocks you from getting high. If buprenorphine is fillin all of those receptors (like a dose over 4mg), when you take an opiate like oxycodone you can't get high because bupe has a higher affinity and will stay binded to the receptors.

Now if you are on a low dose (like the OP at 2mg), not all of your receptors are filled with buprenorphine, so takin something like oxy or h will get you high depending on the amt of your receptors free.

What you want to avoid (but will not "damage" your receptors) is taking buprenorphine while high and dependant on opiates like oxy or h. Since buprenorphine has a higher affinity for the receptors, it will tear the H/OXY rapidly off your receptors causing you to go into withdrawals which are usually worse and more pronounced then normal withdrawals.
 
stuckinaloop said:
Also to the original poster:

All suboxone did was take away from your high (like the above posters said).

Next time skip the suboxone and you'll be higher.

There is a reason people take suboxone its not like combining a few hydros with your oxy haha
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Actually this is debatable. I made a thread on this subject a few months ago. Basically I was asking if buprenorphine can ever actually ADD to the effects of other opioids, or if it always will block or dull them somewhat.

The consensus is that at low doses, bupe can actually have a cummulative effect when mixed with other opioids. The reason is that at low doses, you still will have many opioids receptors which are not occupied by the bupe, so if you take another opioid, it will simply bond to these empty receptors. In this case, you will get the effects from the small dose of bupe, PLUS all the effects of the other opioid which has bound to your empty receptors.

It is when you take higher doses of bupe that your receptors will be saturated, thus blocking or dulling the effects of other opioids.

Now what it up for debate is, how low of a dose of bupe do you need to take to experience this cummulative effect. -DG
 
Too everyone who said I'd enjoy it more WITHOUT the sub: Yeah I know, I do it all the time; the reason why I posted this experience is because I was surprised how nice of a high I still lhad WITH the bupe. I actually felt it enhanced it in those low a dose which is weird because every other time I've taken subs it just kills it for me. I think it was because of the tramadol which is not a "real" opiate; it effects your serotonin levels and mimics opiates on the receptors.

That mixed with the fact that the sub was already wearing off because of my tolerance and how low the dose, plus the benzos and alcohol helped it alot.

But I do know alot about a benzo opiate mix; I've overdosed twice on that mix. Although it's alot of fun i do not recommend it for an inexperienced user. It may sound hypocritical, but I don't want that shit on my conscious.
 
daddysgone said:
Actually this is debatable. I made a thread on this subject a few months ago. Basically I was asking if buprenorphine can ever actually ADD to the effects of other opioids, or if it always will block or dull them somewhat.

The consensus is that at low doses, bupe can actually have a cummulative effect when mixed with other opioids. The reason is that at low doses, you still will have many opioids receptors which are not occupied by the bupe, so if you take another opioid, it will simply bond to these empty receptors. In this case, you will get the effects from the small dose of bupe, PLUS all the effects of the other opioid which has bound to your empty receptors.

It is when you take higher doses of bupe that your receptors will be saturated, thus blocking or dulling the effects of other opioids.

Now what it up for debate is, how low of a dose of bupe do you need to take to experience this cummulative effect. -DG
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This is something I've been very keen to try out but haven't had the guts to yet for fear of precipitated withdrawals. It sort of seems to make sense, as you said there will be a number of receptors free for the bupe to bind to, but won't it just bind to any receptor, empty or otherwise. Because of its higher affinity won't it just replace everything without discriminating between full and unagnoised receptors. Rather than just binding to the empty ones? Even at a low dose.

For example: Say you'd like snorted 20mg oxycodone. For arguments sake 60% of your mu receptors are fully agonised by the oxy. Then you take 2mg Suboxone sublingually. Why will the suboxone go for the 40% of empty receptors and not just mess up the 60% with oxycodone bound to them? Leaving you with say ~20% oxy and ~80% buprenorphine.

Hope that makes sense, sorry, having a bit of a bad day.
 
80mg said:
10AM- The one thing I can't STAND about suboxone is that no matter how big or small the piece; bupenorphine knocks me on my ass! Not in a euphoric stony balogna way; like a sleep all day way. Not cool
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I can definitely relate here. Buprenorphine, while strongly intoxicating, long lasting and quite potent, is not very euphoric for me (even though I had virtually no opioid tolerance at the times I've taken it). To me, it's more of a generic CNS depressant feeling akin to benzos or propoxyphene rather than the euphoric high I get from morphine et al.

It's like the opiate incarnation of cold tofu.
 
Morphoid said:
This is something I've been very keen to try out but haven't had the guts to yet for fear of precipitated withdrawals. It sort of seems to make sense, as you said there will be a number of receptors free for the bupe to bind to, but won't it just bind to any receptor, empty or otherwise. Because of its higher affinity won't it just replace everything without discriminating between full and unagnoised receptors. Rather than just binding to the empty ones? Even at a low dose.

For example: Say you'd like snorted 20mg oxycodone. For arguments sake 60% of your mu receptors are fully agonised by the oxy. Then you take 2mg Suboxone sublingually. Why will the suboxone go for the 40% of empty receptors and not just mess up the 60% with oxycodone bound to them? Leaving you with say ~20% oxy and ~80% buprenorphine.

Hope that makes sense, sorry, having a bit of a bad day.
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He is saying if you take the bupe first in low doses than take the oxy than it may in theory be possible to get a cumulative effect. Now if you take the suboxone after the oxy than you will still go into withdrawals like normal and the amount of receptors open wont matter.
 
I use suboxone patches that release 10micrograms every hour and lasts for a week. This is the only time i ever notice any cumulative effects when mixing with moderate (40mg) doses of oxycodone (insufflated). Interesting mix.
 
Man I hate to be a rain parade and I'm the sorta person who don't bitch and preach but I just gotta say I think its fuckin stupid to even be messing with suboxone if all your going to do is mix it with other opiates,its instances like this that will eventually fuck it up for everyone who is trying to stay clean and don't want to be on a god awful pain in the ass mmt program,the more reported cases of suboxone/subutex abuse there are the more likely the chance that it will get nixed or they'll start even adding more dickey chemicals to it to extend the patent and make you even fuckin sicker,I take subutex because I'm allergic to the dye in the orange ones and I must say its cleaned my life up a great deal,no more bullshit heroin deals,bogus junk,money thrown away,threatend,held at gun point,robbed,who the fuck needs all that just because a bunch of immature careless people have to abuse every fuckin pill that hits the shelves then when somthing bad happens they expect society to wipe their ass for them by complaining thus alerting people that have absolutley no idea what the fuck their talking about saying"we must strive to have this dangerous drug removed from being sold"like they've done with so many other things,take pods for instance,if it wasn't for fuckin stupid immature mis-informed assheads dying from the shit they would still be cheap and semi-legal even tho technically they are and were illegal it wasn't until fuckin stupid kids start bringing attention to it then big brother has to put a stop to it,every person who ruins it for everyone else should have their ass beat if such a thing were possible,it just really pisses me off
 
Yeah....like basically everyone else said....don't take suboxone with other opiates. Literally all it will do is stop the full agonist opiates from working properly. In fact, I'd bet those roxys did pretty much squat for you. You were probably just feeling the suboxone and the tramadol. For some reason tramadol still seems to work a bit after you take suboxone, not sure why, but oxycodone sure as hell doesn't.
 
The only reason the naloxone is in the subs is as a deterrent to stop people from banging it....the buprenorphine acts on two of the three opiate receptors in the brain, with the naloxone blocking the third, "get high" receptor. But with a high enough dose of oxycodone, (or whatever other opiate does it for ya...) the naloxone can be "knocked off" and you CAN get high! I speak from experience. It does depend on how much suboxone youve taken and the time elapsed, as well as what youre tolerance to normal opiates is.
 
Sorry to bump an old thread but I just ate 1 whole OC(NOT OP) 80 and a quarter of another 80. As I also take very very small piece's of subs (1-2mg) and it was taken this morning around 10am. I will report back if it was blocked or I felt it. :) crossing fingers for full out fucked up new years :)
 
Yes, xanax makes subs soo much better, really any benzo but especially xanax(and not like a high for me anyway,it just makes ya not wanna go out and get HIGH)...i've been a bitch without my ben'z around, I need to call my dealer. And some people say low doses of bupe enchances whatever they take(I mean it could, it's not like 2mg is a blocking dose, you are really getting only like 500MICROGRAMS,which is a pain dose, not a blocking dose) and Tramadol is the only opiate you can feel while on Subs(even high doses) I've never tried it...So overall nice combo if you have a tolerance, minus the alchohol,I just don't like alchohol on opiates, it dirty's up the buzz for me.
 
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