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2CD and possible MAOI properties?

MeDieViL

MeDieViL

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I've been rather interested in 2CD's property to extent the duration of other compounds lately, but i'm not sure how this is possible.

Is it possible that 2CD acts as a MAOI? That would explain its ability to potentiate other drugs, but that would also make it quite dangerous to mix with other substances.

I hope anyone can shed some light on this.

Thx!
 
i also doubt it, i have taken 2C-D with moclobemide safely on several occasions as one might expect full inhibition of MAO-A and partial inhibition of MAO-B almost triples its oral potency, it may possess some MAOI activity (as does every amine which ties up the enzyme) but i doubt its of significance.
 
Well the 2,5-dimethoxy substitution pattern also has pressor activity (eg methoxamine) so I can't say I'd be happy taking it with an MAOI, even a competetive one like moclobemide
Click to expand...

Hmm, the body of experiential literature strongly indicates that pressor activity exists with pretty much all of the 2c-x series, at least potentially ... my impression from the 2c-d literature is that it's probably milder in this regard than e.g. 2c-i or 2c-e, although this may be due to the lower potency of the former; I haven't read the German 2c-d (LE-25) literature where they used much higher doses.

Although -- personally -- I would not take these chemicals with moclobemide regardless.
 
right from a HR standpoint i would never recommend anyone do what i did, but i can say that i experienced no worrisome symptoms (tachycardia and/or hypertension) although i was also not measuring either of these things so i can only go by the fact that i felt totally comfortable.
 
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