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2C Family IV or IM administration

Selggurkim

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Sep 17, 2012
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Greetings everyone,

I am looking for any information (either first-hand or secondary experiences) on IM or IV administration of any of the 2C-X family. I have hunted through BL & other online sources for information with some (albiet limited) success. I understand that many people support sticking with the oral administration method but for some research I am conducting I need information regarding these less used administration methods.

I am particularly interested in the dosage amount used and to what extent effects were felt. Any ill natured side effects should be included as well.

Cheers!
 
I have IM'd 2c-E. You definitely would not want to IV it in my opinion.

The onset for IM is incredibly strong and fast, I wouldn't want it to be any quicker. And I have only done this twice, and overall do not recommend it.

From just 5mg IM 2c-E, I projectile vomited during the come up.
 
I've never done it or heard of anyone doing it before and due to Captain's post I don't think I would ever try it. I'm just posting here to subscribe to the thread and see what posts come of it as I'm pretty interested in hearing from more people with first-hand experience with this.

-PJ
 
Thanks for the interest freeskier and thank you Captain for the experience information. I know it is uncommon to use either IM or IV with 2c's. I am not asking for my own personal use but rather as a research for some analysis / writing I am working on. I hope others will contribute !
 
Freeskier - This is a long term paper that is being put together as a scientific study so don't expect anything before fall of 2013 ! But I will add you as a friend on here so I can update you along the way to the finished product if you would like?
 
IM can be decent, bit fast of a come up for my taste. I IV'd 7 mg of 2C-T-7 back in 1999 and that was unbelievably intense. Amazingly I did not vomit, and not so amazingly I never repeated the experiment. Tread with caution.
 
These drugs are too strong to snort, let alone shoot up. Consider yourself warned.
 
[Dislaimer: Please use proper sterility procedures when injecting these or any other compounds. It is very important that you filter the compounds properly with micron filters, and that you follow high standards of injection hygeine.]

I have a lot of experience IVing and IMing 2C-E, 2C-T-2, and 2C-C. Let me first just start by saying that administering the 2C-x class via injection is not for the faint of heart, it is extremely intense. You want to make sure that your doses are very low to begin with to get a feel for how this ROA works with these compounds. Jumping in at the deep end can be terrifying if you're not familiar with the sudden physiological and mental shift, and even if you are familiar, you can still be caught unaware by cockiness.

I'm going to address IV administration first:

Out of all 3 of the above compounds, I would say that 2C-C is the most physiologically demanding compound via this ROA. The effects on your cardiovascular system will take you by surprise. The speed and strength of your heartbeat alone is reason to make each injection happen mindfully; you will not be able to just plunge it in within a few seconds like you would shooting dope. Because of the speed at which the drug hits you, you will automatically recoil from injecting it too fast and have to take a breather.

2C-E and 2C-T-2 can be intense on the cardiovascular system also, but they don't have the same "emergency factor" that 2C-C does, and you will know what I'm talking about if you've done it. 2C-C is extremely heady and rushy, and it can blitz you mindless. Because of this, it feels like a very different drug when injected versus oral/intranasal. 2C-E and 2C-T-2 IV on the other hand feels a lot closer to normal ROAs than does 2C-C, but of course they are far more intense via this ROA and there are still some differences in the experience.

Now about IM administration:

Although it may seem counter-intuitive, I believe IM administration to actually be the riskier of the two methods. The reason for this is that there is a greater time lag before effects hit with intramuscular injection, and you can easily dump a whole dose in way too fast without getting the biofeedback to understand how your body is going to cope with the extra load. This is especially true with 2C-C because of the cardiovascular load, where you can inject a certain dose, and then find yourself out of your depth as your body begins to absorb it.

A much better way to do it is to start with a small dose, and inject that properly, not too fast! The instant you feel it might become overwhelming, stop. You can always go back later and try a higher dose if it wasn't intense enough for you. You can then stagger your doses, for instance by sharing a small dose between the right and left deltoid muscles. This will let you gauge how quickly your body absorbs these particular compounds from your muscles, and to get a better idea of what your next doses should be. The kinetic are different between IM and IV, but the peak level intensity is what you want to consider.

Once an IM dose hits, it feels almost the same as an IV dose, just without the same degree of insanity. It actually feels pretty damn smooth and it is a nice (but unnecessary) way to experience these chems, although the rush of IV provides more pizazz and fireworks. They can actually stay in your muscles a pretty long time and you can notice this by massaging your injection spot a couple of hours in and experiencing a sudden boost in effects.

Both ROAs:

The experience of injecting a 2C is pretty fucking insane, that's all there is to be said really. It can also be pretty fiendy, so don't be surprised if you find yourself shooting up every few hours and spending several days in a 2C-hole. Tolerance matters here, because you will find yourself chasing a high that you can't reach again without putting great stress on your body. No matter which route you choose, it is very visual, very synaesthetic, and even sometimes borders on dissociative.

The visuals are like they would be if taken orally, but more intense and 3 dimentional. Visual-auditory, visual-tactile, and auditory-tactile synaesthesia was greater than normal. Whilst 2C-E is always very clear headed via IV/IM, 2C-T-2 is incredibly immersive and sometimes bordered on dissociative and outright reality-shattering. Don't be surprised if this puts you on your ass. 2C-C is just 8o or 8( (without any real visuals to speak of). It's like chasing a hyperdimentional unicorn you can't catch, and it becomes almost dangerous to do so because of the stress on your heart.

Coming back to intravenous: my friend and I used to call this route of administration a "Raging Vein", because of the peculiar combination of circumstances that followed an injection. Even when the shot was completely on target the resulting vasocontriction and high incidence of collapsed, distended, and burst veins caused the material to linger in venous pouches, which could then be massaged throughout the experience to cause a second peak. At the same time, this compound burns your veins, and successive shots in to the same vein can eventually become extremely painful to the point where it is intolerable to make any further injections. The vein becomes quite swollen at the site of injection, whilst all your other arm veins are hiding due to vasocontriction. All this, whilst chasing the dragon of an ever elusive high whilst multiple syringes filled with crimson liquid from half-used shots line the room caused us to think of this nomenclature.

As you can see, intravenous administration is not good if you plan to be using these compounds regularly, because you will end up like I did, with no surface veins left. It has taken me a couple of years to get back my veins, and I don't ever intend to inflict that damage upon myself again. I recommend you avoid this method, but if you must try it, then do it sparingly and take all the necessary safety precautions. I also similarly warn you away from intramuscular due to the greatly heightened risk (over IV) of infection if you didn't follow strict sterility procedures. In fact, I would say that in general, intravenous is the safest method to choose.

All this said, oral is now on par with rectal as my preferred ROA depending on the kind of trip I want, and intranasal is the worst given the pain it causes and the damage to the mucous membranes. Oral feels very nice and smooth, with enough visual and mental intensity to satisfy for long classical trip. I prefer it to IM because with IM there seems to be something lacking. Rectal is far preferable to IM for me for fireworks, because the comeup is easier to handle, but the intensity is still there and even exceeds it in some ways. For instance, the rush you get coming up through your central meridian - all the way from the base of your spine at your ass hole up through your "chakras" to your crown is a unique and incredible sensation that isn't there with IM.

If you choose to experiment with injecting these compounds, proceed safely and make sure you have everything you need (clean needles, clean syringes, micron filters, sterile vials, alcohol wipes). I cannot stress this enough. I met up with the same tripping partner a couple of months ago, and he told me that he got pretty worried about the reckless behaviour we were engaging in. Weighing up the pros and cons, and knowing that I can get exactly where I want to with rectal/oral, I now don't see any need to go back to injection.
 
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I have IM'd 2c-E. You definitely would not want to IV it in my opinion.

The onset for IM is incredibly strong and fast, I wouldn't want it to be any quicker. And I have only done this twice, and overall do not recommend it.

From just 5mg IM 2c-E, I projectile vomited during the come up.


The same thing happened to me, i ived 2c-i and it was intense but threw up immediately, I miss it though it was fun afterwords
 
I can't wait to try IM'd 2C-C for one.

Well I tried that, felt constriction in the chest area and labored breathing. Not resp. depression, more like a strange kind of panting though not that fast. Disliked it all actually and it definitely didn't seem worth the effect. I can't remember what dose I used. Around that same general time I tried 2-FMA via the same route and had little or no issues with that, so my guess is that it is not a bad stimmy reaction. Don't know what to make of it.

I think those were the only times I IM'ed PEAs. And I doubt I will try it again.
 
selgurkim said:
I am particularly interested in the dosage amount used and to what extent effects were felt. Any ill natured side effects should be included as well.

If you've searched I'm sure you came across my attempt to describe and quantify IV 2c-e (or at least I came across it when looking to see if there was anything to merge this into), if you want more than that, I'll try to answer what questions you have.
 
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I was around someone who IV'd 4-6mg's of 2CP. I attempted to talk them out of it with out any luck. I do the next best thing and offer to be a sitter. Half-way through dose he stops and realizes this isn't like anything else he's ever IV'd before. Starts to really trip himself out. Can't walk, nothing he is saying is making much sense but he is talking still. Breathing gets heavier, sweating everywhere. I tell myself if he doesn't improve within the next 30 mins. I'll dial 911.

He starts making sense about 45mins after he'd IV'd. Still sweating, breathing heavy and says "my heart is beating extremely fast." I offer him some water and turn on some music. After an hour or so after the dose he seems to be doing good. Complains of tightness throughout his body for the rest of the trip. After about 8 hours he decides he'll go home.

Calls me up the next day thanking me for being there.
 
The feeling I got about both psychedelic tryptamines and psychedelic PEAs via injection from posts 'historically' during the time I have been around PD is that:

first it seemed to be considered unwise...

... after that people reported it to be 'certainly possible'...

... then it still really didn't seem like a good plan.

/
Anyway, things like the simple N,N-substituted tryptamines with limited action seem to be fine IM'ed at least - like DPT or DMT. And I still plan on trying that with my synthetic DMT.
Well I have still yet to try my 4-HO-DMT but it is probably hardcore enough without injecting something like that. I have tried high doses of 4-HO-MET orally and apart from economical reasons I don't think it needs to get better than that. 4-substituted tryptamines work excellent in almost any way.

5-substituted tryptamines I would never inject.

2C-T's hmmm well I can see how other ROAs than oral would be worth exploring but I would suggest plugging is a solution.
Same would probably go for 2C-E.

Plugging 2C-D was alright although I had tolerance when I did it and always had difficulties getting something near a +++ from the compound.
 
IDK how anyone would consider doing this, being that its not a feindish drug that make you not really give a fuck about the purity/sterility of what your injecting, and its a psychadelic.

Plugging 2c-c was pretty fantastic, although it burns like a motherfucker. Fast come-up, definately more potent, and it seem'd like there was a whole lot less nausea, at the cost of the jarring nature of it hitting so hard so fast.

I think the best way is oral. No fucking way i'm injecting some rc made in chinese(not exclusively though) labs by mofo's i know nothing about, or the purity of said drug (but hey i won't inject recreationally in the first place no matter what the substance).

Plugging works pretty well ime, but you won't want to do it again (at least with 2c-c ime) since its like plugging hot sauce up your ass. I tried it at lower dosages a few more times (~5-8mg 2c-c), and it was better than oral, but the burn just ruins it for me. Nothing else i've plugged burns like that, including the time i plugged ~120mg of mescaline hcl.

And on a semi related note, plugging ~12mg 2c-c and then about an hour later ~10mg of 4-aco-dmt, was prob one of the biggest mistakes of my forays into dosing psychadelics. No fun at all.
 
Maybe it is not hugely on-topic but how was the advantage of plugging mescaline (I've been wondering about that) and what was so wrong about that last combination you mentioned? It doesn't sound like a fundamentally bad plan...

I guess regarding safety of injecting compounds like this, your argument about shady labs sounds sensible and I do feel divided on the subject, but if your preparation is micro-filtered, everything injected should be properly water-soluble. There may be some difference between having impurities subjected to first-pass metabolism or not but nothing is any guarantee.
Anyway personally I am less worried about impurities affecting me via IM than pharmacokinetics and things like adrenergic action really doing a number on the cardiovascular system.

My trial was not done in a positive and responsible mindset, it was a dark time for me anyway. If you care less, it becomes less of an issue to try out something like this apparently.
I don't actually trust the 2C-C itself acting via this ROA let alone impurities.
 
These drugs are too strong to snort, let alone shoot up.


Thank you for contributing. But your "information" is 100% opinion. Every person reacts differently to substances. You will find thousands of folks (if not more who are not only willing but enjoy insufflating 2C's.


@ Solipsis : Thank you for some quality information. I am searching for dosage amounts and the results that followed. Of course sketchy labs and basement chemists do provide unknown variables / dangers. If you care to share I would like to know the dosage you attempted and the effects you have. Even if your memory is hazy, every bit of data helps.

If you've searched I'm sure you came across my attempt to describe and quantify IV 2c-e (or at least I came across it when looking to see if there was anything to merge this into), if you want more than that, I'll try to answer what questions you have.

I did read though your previous experience. I suppose more specific questions would simply include comparisons to using the same substance in other administration methods. ie. IV at 3.5 mg is about = to X taken orally = Y taken rectally = Z IM etcetc

Thanks!
 
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Hmmm I'm a bit skeptical about translating dosages, by that I mean of course we all need a starting point as guidance but it is still best to start a little under that because the effects just tend to be different and not only proportionally stronger or weaker.

Perhaps I tried something like 15 or 20 mg of 2C-C. I am fairly positive it was not lower than that, although I strongly suggest you assume it was anyway. You see, perhaps you consider every data worthwhile as something to go on... falsely remembered data would only provide you with a ballpark guesstimate you could have come up with yourself with an ugly margin.

Even more so: IM admin comes up fast enough to take little effort in a trial. So just suck it up and give it an extra 30-60 minutes for lower dosages, to see how they land you. The only sacrifice is a few needle jabs. And that should always be worth avoiding an OD!
 
Maybe it is not hugely on-topic but how was the advantage of plugging mescaline (I've been wondering about that) and what was so wrong about that last combination you mentioned? It doesn't sound like a fundamentally bad plan...

I guess regarding safety of injecting compounds like this, your argument about shady labs sounds sensible and I do feel divided on the subject, but if your preparation is micro-filtered, everything injected should be properly water-soluble. There may be some difference between having impurities subjected to first-pass metabolism or not but nothing is any guarantee.
Anyway personally I am less worried about impurities affecting me via IM than pharmacokinetics and things like adrenergic action really doing a number on the cardiovascular system.

My trial was not done in a positive and responsible mindset, it was a dark time for me anyway. If you care less, it becomes less of an issue to try out something like this apparently.
I don't actually trust the 2C-C itself acting via this ROA let alone impurities.

The advantage was a quicker come up, and imho less nausea, along with increased potency. Really it was just for noveltys sake, and i am on the line about whether or not i'd do it again. It was interesting, i just get far more utility from taking ~100-250mg orally with a low-med dose of a 4-sub tryptamine an hour later, or half a tab of lsd at the same time (talking about mescaline).

As far as the 2c-c/4-aco plugging, i pretty much was in the same situation you were. It just opened up a can of worms in the wrong place, at the wrong time, when i wasn't able to face what i was understanding about myself. Just irresponsible dosing, not so much the drug combo or roa. But then again, fast come up psychs just aren't for me. I am on the fence about ever vaporizing dmt again in my lifetime after the same kind of situation. So your right, it was more me than the drug/expirence. I guess my point was that it was far more powerful than expected, and i was in no condition to deal with that. Psychadelic abuse/misuse to sum it up.

I agree you should micron filter everything you put in your veins, but not all impurites, sometimes toxic ones are water insoluble. Not trying to scare anyone, just know its clandestiely produced, versus pharmaceutical. But thats non-exclusive as far as injected drugs produced illicitly/semi-illicitly. The degree of harm done is not quantifiable, so its a bit alarmist to say don't do it, but you can't say its safe or relatively safe either. Each person decides how much risk to take.
 
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