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2C-D tolerance and what to do about it

ClintHC

Greenlighter
Joined
Jan 11, 2011
Messages
14
Howdy, I'm new to these forums and hope to stick around.

I recently purchased 500mg of 2C-D and 100mg of 2-C-T-4. I've done 10 doses of the 2C-D and 1 dose of the other over the past month, and they all had little to no effect.

I started with several very small oral doses on the first day and worked my way up from 0.1-1mg to 30-39mg, taking 2-C-T-4 that night and 60-69mg 2C-D the next day.

The effects were very mild, either inexistant or akin to mild drunkenness. When I noticed that relatively high doses still weren't doing it for me, I switched to rectal administration, which resulted in more prolonged and noticeable effects, but they remained too mild for my enjoyment, even up until ~100mg rectal.

Specific notes of the doses, methods of administration, effects, and the time periods of ingestion are at the end of this post.

I know that my source is good, and I've felt this type of tolerance in the past to other drugs as well; I did MDMA once with no effects, magic mushrooms at least three times with little to no effect, and THC pills, although smoking pot and drinking alcohol do have effects.

My question is, how can I get proper effects out of these chemicals? I'm thinking of experimenting with Syrian Rue as an MAOI, but could not find anything on this subject, only finding information about how 2C-D and other research chemicals themselves can act as MAOIs.

The other options I have thought of are taking immense doses, which seems unwise, and trying insufflation, which seems painful and unnecessary. Thoughts?

Responses are greatly appreciated ^_^

=======================================================

Day 1

Dose 1 - T+0:00 - 0.1-1mg dissolved in water, ingested - brief small feeling that something is different

Dose 2 - T+1:11 - 0.3-3mg, same method and effects as dose 1

Dose 3 - T+1:50 - 0.6-6mg, same method as doses 1-2 - didn't notice anything different this time, no effects

Dose 4 - T+5:40 - 10-19mg, ingested powder directly - no effects

Dose 5 - T+7:03 - 20-29mg, direct ingestion - feeling like mild drunkenness

Dose 6 - T unknown exactly - 30-39mg, oral gel capsule - brief mild CEVs

Dose 7 (2-C-T-4) - T+12:18 - 20-29mg, oral gel cap - no effects

Day 2

Dose 8 - over 12 hours after dose 7 - 60-69mg, oral gel cap - feeling that something is different, smoked pot almost an hour later, no synergy felt

Day 6

Dose 9 - 10-19mg, rectal gel capsule - feeling of mild drunkenness, later like mild pot high, heavy-headedness, relaxation, all very mild

Days later

Dose 10 - 60-69mg rectal, no effects

Day 30

Dose 11 - ~100mg rectal - heavy-headedness, feeling of dissociation with world, all mild and remaining for less than an hour
 
Last edited:
Spend some time letting your tolerance go down.

When doing a titration, it is necessary to wait at least two days between subsequent dosages! Anything else is a waste of time and, when dealing with a compound less benign than 2C-D, potentially dangerous.

Also, this is BDD material.
 
Just do one 20mg dose of 2c-i or 2c-e and let it speak for itself.

Also, wait at least 2 weeks in between tripskis, broski
 
You certainly don't want to snort 2c-d given the dose involved and how much other 2c's burn by that route. Rectal should work as well without the pain, but as others have said tolerance to psychedelics builds quite rapidly.

Just curious-Why are your doses stated as .1 to 1 mg, ect?
 
Just curious-Why are your doses stated as .1 to 1 mg, ect?

I'm one of those dumb people who is using a scale that is only accurate to the centigram, meaning the smallest unit is 10mg. So if my scale reads 1cg (10mg), then it'll keep showing that value until I hit 20mg, so I can't get an accurate reading unless it's a factor of 10 and I keep on adding substance till it hits that value, something that is a major pain since the scale just turns off while I'm adding. Yeah, *facesmack*.

Spend some time letting your tolerance go down.

When doing a titration, it is necessary to wait at least two days between subsequent dosages! Anything else is a waste of time and, when dealing with a compound less benign than 2C-D, potentially dangerous.

Also, this is BDD material.

I didn't think tolerance was that big a deal for the first 2 days since I was taking such small doses at first. But as you can see, my last two high doses were at least 2 days after the previous times I tried. It's still not enough time according to Psyke though.

And my apologies for posting here. I found the post about 2C-D being an MAOI in ADD so just assumed this was where this should go.

So I guess I'll wait 2 weeks and try another large rectal dose, see what happens.
 
stop using the drug now is my advice.
spend $40 on better scales off ebay
 
I recently purchased 500mg of 2C-D and 100mg of 2-C-T-4. I've done 10 doses of the 2C-D and 1 dose of the other over the past month, and they all had little to no effect.

I started with several very small oral doses on the first day and worked my way up from 0.1-1mg to 30-39mg, taking 2-C-T-4 that night and 60-69mg 2C-D the next day.

The effects were very mild, either inexistant or akin to mild drunkenness. When I noticed that relatively high doses still weren't doing it for me, I switched to rectal administration, which resulted in more prolonged and noticeable effects, but they remained too mild for my enjoyment, even up until ~100mg rectal.

To me it sounds like your 2CD and 2CT4 is heavily cut. Of cause maybe you are just one of these people who have a very high natural tolerance to phenethylamines. I have heard of that before.
Maybe try to give a 40 mg 2CD dose to a friend to establish if it´s the compound or you there´s something wrong with.

I never before heard about people not getting any effects from MDMA?! How much did you take?

My question is, how can I get proper effects out of these chemicals? I'm thinking of experimenting with Syrian Rue as an MAOI, but could not find anything on this subject, only finding information about how 2C-D and other research chemicals themselves can act as MAOIs.

I never read about people mixing phenethylamines with MAOI`s. But I think it might be dangerous since they are more stimulating than tryptamines, which is what is traditionaly mixed with MAOI`s. Like in Ayahuasca.
You can read more in Erowid´s Harmala vault, in case you didn´t know:
Link to Erowid vault about MAOI/Harmala

Be carefull, MAOI`s can be dangerous.


The other options I have thought of are taking immense doses, which seems unwise, and trying insufflation, which seems painful and unnecessary. Thoughts?

I have tried to insufflate 2CD. Don´t do it!! Most phenethylamines burn like hell.
Besides from that:
My 2CD was very "light" fluffy powder, and it was like snorting black pepper.
I sneezed even before I got 1/4 of the line up my nostril and blew the rest of the material all over the table! What a waste :|

I actually think you should have asked this question in Psychedelic discussion.
 
2ct4 is extremely active on me, i find the dose response curve pretty hardcore too
for everyone eklse too it was very intense at medium doses. i think you're buying shit, either mislabelled or cut chemicals
 
I never before heard about people not getting any effects from MDMA?! How much did you take?

I took 1/4 pill to see how sensitive I was and if I would react negatively, then an hour later I took the other 3/4, and a bit later an entire other pill. I got absolutely nothing from it. I'm relatively certain it was good stuff because I knew others who took it from the same source and said it was the real thing.

I've experienced tolerance like this to other substances too. It's mainly the trend that makes me lean toward that explanation.

2ct4 is extremely active on me, i find the dose response curve pretty hardcore too
for everyone eklse too it was very intense at medium doses. i think you're buying shit, either mislabelled or cut chemicals

I'm mostly sure it's good stuff since I looked the place up on a referral-only site that a lot of people here have probably heard of and everybody said it was top notch in service and product. The service truly was amazing.
 
Some people are naturally tolerant to a fair number of drugs - I am not sure if this only applies to the enteral (oral) route of administration but it might be way different if you insufflate, although it's not a good sign that you also had little effect plugging...

I've heard about people being very insensitive to the effects of acid as well. Sometimes it's because of duds but at other times I guess it's just due to a personal makeup... genetic / biological or whatever.

Also questions about 2C-D and 2C-T-4 are hardly BDD material, general hardheadedness might be so I guess its okay in both fora.
 
Just an update: 27 days after my last dose, I took 60-69mg 2C-D dissolved in a bit of water sublingually, holding it in my mouth for 1 hour and then swallowing. This worked and I had my first psychedelic experience.
 
so did the trip completely blow your mind open?

ive always wondered what it would be like to do a 2c for the first trip. i did mushrooms for my first time and it was amazing (i thought i actually understood how energy and mass were the same thing). the second trip was 2c-i and it was good but nowhere near the same (and neither were any of my other mushroom trips!)
 
It blew my mind, but not as much as other drugs probably would. I experienced trailing, and colors started to breathe and flow into each other in a way. I also experienced many thoughts and emotions. But I didn't have much of a deep experience.
 
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