• MDMA &
    Empathogenic
    Drugs

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2025 will be the year of new MDMA-like RCs. (Fuck you RC companies!)

🤨 So dr. Methyl is the story teller, but Phobos really snorts 50 mg aMT.

Calm yourself 🙏, lots of people develope non working olfactory s in live,
especially since COVID. Phobos must be one of em. Or a Hard-Nose !
 
🤨 So dr. Methyl is the story teller, but Phobos really snorts 50 mg aMT.

Calm yourself 🙏, lots of people develope non working olfactory s in live,
especially since COVID. Phobos must be one of em. Or a Hard-Nose !

I used aMT well before COVID hit.
Sadly, I have not been able to find it for about 9 years.
Not sure if that's a good or bad thing.
 
I used aMT well before COVID hit.
Sadly, I have not been able to find it for about 9 years.
Not sure if that's a good or bad thing.
So a Hard Nose it is, i snorted 2C-C en D but aMT.
That s tough, does it linger like the smell of the bag,
where its has been in 25 years.

Yeah i don t like the stuff obvious. And it still smells as🖕
 
25/ 30 year s ago MDMA was euphoric, abuse it declines rapid to disgust.
Not for Serotinergic s just a imprint it made over time. So after a long break.
Methylone/ bk-MDMA i was able to enjoy. A while, got banned, why ?

Now can t think what changed brain chemistry wise, but euphoria.
Nowadays i get only from Lysergic s, tried 5-MAPB and other Serotinergic s.
But it s not the same, the table has turned. In favour of Lysergic s.
I agree Methylone/bk-MDMA was pretty fun.

As mentioned already its defiantly not on the level of pre-abuse MDMA euphoria type, but I remember I was pleasantly surprised after first trying it. 300mg's from memory was a good first dose.
 
I agree Methylone/bk-MDMA was pretty fun.

As mentioned already its defiantly not on the level of pre-abuse MDMA euphoria type, but I remember I was pleasantly surprised after first trying it. 300mg's from memory was a good first dose.
The comparison would not be fair to MDMA, but later on.
Stopped MDMA for some years, so had no Tuesday s drained Serotonin.
Lack of sleep for some time.

Then bk-MDMA became a easy to get RC, and its effect s felt,
apart of the lenght as the better of the 2. Its more relaxing, felt
less forced a softer experience. A perfect alternative for Alcohol imo.

But i never abused bk-MDMA like his brother, 150 mg,
maybe a 75 booster and to bed. Didn t rack my sleep big +
 
Pretty sure rolls back in the day also had meth and a downer plus the mda/mdma. I'm now too cautious to intentionally combine those and pure mdma, while amazing af, doesn't make me feel as strong a "high" but same euphoria. Perma-tolerance probably a factor tho.
 
Worst perma-tolerance is nitrous ime. Can quit for years and still can do hundreds an hour without wah-wah
 
Hi everybody,

I am a clandestine chemist and during 10 years I've made plenty of new drugs : first we discussed about the molecule with neuropharmacologist, then I made it, then I tested them on myself until low/medium dose before destroying them in permanganic acid. I've never sold anything, just single test to see the activities and the effects like shulgin did. My goal was the release a PiHKAL-like book with all the molecules beyond phenethylamines and tryptamines including from PCP-like to opioids. but I decided to never publish it because of... RC Companies ! 5 years ago I stopped doing this kind of research on psychoactive but still doing clandesting chemistry to make new anti-cancers synthesis pathway or making new human pheromones.

I hate the RC compagnies because of the complete lack of proffessionnalism not because of the buisness of selling drugs. Did you remember the website "HCl Research" based in Germany how proffessional they were ? They were discrete and shipped only good molecules probably made in germany. But after this time when the new drug "mephedrone" arrived on the market everything broke up into pieces and the full market went completely bullshit. The chinese lab were competing togheter and made impure product at the lowest price possible and send kilograms to hundred of new website (mainly UK-based), then the clubber bought from there and resold the mephedrone at the local parties. Neither the maker nor the website reseller nor the clubbers have any knowledge in chemistry or basic pharmacology, they just want their little bags of drugs. And the chinese knew that and started doing absolute shit.
They sold very impure products ( a batch of 4-MeO-PCP was analyzed and contained 40% cyanide) claiming its 99.9999% just because they know the product will finished on the street and will be never analyzed by the customers. When a drug is banned they made analogue without asking the neuropharmacologist or doctor about eventual toxicity and started selling neurotoxic mephedrone analogues. For exemple they sold a synthetic cannabinoid that will be cleaved to naphtylamine by the liver and any person who has little knowledge in toxicity knows its one of the most potent carcinogen. But they didn't care, they sold "not for human consumption" anyway, the cancers are not their problems.
But at the times there was still a red line to not cross : selling deadly opioids. After a few years the red line was finally crossed and they directly sold fentanyl analogues by kilogram directly to the mafia leading to the well known fentanyl crisis you have seen in the media...

About 10 years ago I was discussing with a russian chemist about making the benzofurane analogue of MDMA. Now they are known as 5-APB and 6-APB but back then I called them "furamphetamines". He want to make the 5-isomer with the oxygen in para but me I prefer to let the oxygen in meta because of PMA toxicity. So we bet who was right. One day he wrote me he won the bet because the molecule is finished and has MDMA activity without the need for N-methylation, he also told me its even better than MDMA. But me , I finished my molecule and test it and YEEEES it is active and MDMA-like ! So I published the molecular structure on my blog along with the bioassays and commentaries.

A few month later I found a website selling what ? Yes, 5-APB AND 6-APB under the fancy name "benzo fury", ours furamphetamines !!I don't try to let beleive I invented the molecule, no because they were already patented, but I was the first to try and explain the activity. So based on our research the companies ordered kilograms to chinese labs and started making huge amount of money with no respect to the molecules. I ordered a sample and analyzed it and it was only 85%, the rest is other isomer and unreatced products... From now I immediatly removed the blog and did not published anything anymore but I kept doing research.

I made and tested a lot of new rings : benzimidazole, benzisoxazoles, and so on. And I find a new ring with MDMA-like qualities but never plublished anything. And guess what ? Today I find the ring on.... Wikipedia ! And with plenty of other rings ! Apparently there are new neuropharmacologist that made new analogues, tested them and published in 2024. I haven't read the pubs yet, but it is question of time for the RC companies to read it and ordering kilograms of new molecules.... I bet its that will happened in 2025.

I thought researchers in universities stop publishing after Ralf Heim discovered bomamines (NBOMes)and RC companies spread them all across the world and killed thousands of people of overdoses due to the unsafty profiles of N-BOMe. By the way, with the help of a friends who works with IA neurologic software, I made new N-alkylated 2C-X with the activity starting at 25 ug ! Way more potent than LSD ! But if I publish the structure it will be completely legal in all the world because not based on N-Benzyl mioety and RC compagnies will sold them again and killing a lot more of people...

Now I am fed up with how the RC market has turned and how the product are sold. It can be easy to start a new website selling controlled molecules analyzed by GC/MS or NMR and selling to intelligent people but no ... money talks....

And who knows what happened to the website "blacklight.in" for advanced drug discussion ???

Thank you for reading,

Dr.Methyl
Why 2025 specifically?
 
Brahma took MDMA off the market because it was making people gay. Chem_G, Is that an accurate assessment on my part?
 
I thought they basically disproved “downers” in ecstasy pressed tablets. Much more likely to be MDEA which was known for having a “stoning” couch lock kind of effect.

Oh yeah and be sure to watch for those tablets speckled with brown speckles because those “heroin-based” ecstasy pills. Riiiiight.
The brown speckles in Salmies, first real big commercially MDMA pill.
Before they even il-legalised it, in NL. The brown speckles where Salmiak candy.
As the maker could make excellent MDMA, later on MDEA.
It was that he did it on a boat in a Amsterdam canal, that got attention.

But had a problem, binder, ordered a load of Salmiak candy powder.
And used that, never had one but they tasted Salmiak, according to a old mate.
Who was named after it. SalMIES.
 
I keep on pointing out that AMT is a chiral compound. One enantiomer has decent 5HT2a affinity, the othet does not. So simply resolving the enantiomers yields a pronent entactogen.

Taken to it's ultimate conclusion, (R) 7,α-dimethyl tryptamine (7-methyl AMT) which has long been known to be a potent entactogen. Upjohn researched the class as potential antidepressants during the 60s.

Now, I don't know exactly HOW potent (R) 7,α-dimethyl tryptamine IS, but the limited amount of researh notes some intersting details:

1-Intdoruction of a 7-methyl moiety increases the monoamine release/reuptake values by an order of magnitude.
2-Both enantiors are equally potent in this action
3-The (R) enantiomer has a much lower 5HT2a affinity than the (S enentiomer.

I've been told that vaped, 10mg was most similar to MDMA. But that said, I suspect it's synthesis means it isn't an obvious alternative if profit is the sole motive.

BTW it overlays 3,methoxy-4-methyl-amphetamine which HAS turned up as an RC and guess what? Pretending to be MDA,
 
I admit I do not know a whole lot in the larger scheme but a couple of these vendors are as good as robin hood to me. Got to experience alot of stuff I would have never came across 'on the street' usually for a price per dose that I would never repeat on the streets either.

I agree mephedrone was a problem --- methylone however I was fond of so that is just me being subjective. Liked Methylone better than MDMA in fact (not mg for mg but dose for dose). prefer it to MDA as well (of course the MDA came from someone elses source therefor is ? )

*edit* I will double down and say I had more fun with 25i-nbome than I will likely ever be able to afford to with LSD. Triple down and say I am sure the benzo rc's saved many people from being under the thumb of an authoritarian doctor.

Lying about purity and improper synths are no good of course. What is the alternative hope that it catches a patent and trickles down to me? No thankyou. I did happen to lose my sense of smell to COVID and good riddens, most smells are not good IME.

I would say it is due dilligence on the researcher's part to make sure they are acquiring what they presume to be acquiring and to take all necessary precautions.

Are you really mad because the majority of ppl are stupid and ruined a good thing, is it the darwin lemmings? Otherwise I dont get it --- what I mean is yeaa fuck them and I am in line patiently lol -- also I remember "benzo fury" and being pissed it was not a benzo!
 
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