2,5-dimethoxy-4-isopropyl PEA?

[Phener]

This is quite a discrepancy!
Makes me question whether a vendor may be sending out something else as 2C-iP?

Hmm precisely, not disputing trip report always keen to hear about activity of 2C-IP always was one my favorite "why didn't shulgin explore it chems!?"

could well be something like 2C-TFM or anything I guess ?

 

[TheAzo]

The long duration and slow onset is not consistent with a 2C-X, but a DOX. It may be DOIP. The dose is given in Pihkal (p. 650) as active at about 20-30 mg.

This makes a lot of sense. Luckilly it was only a factor of 2 more potent instead of a factor of 20 (like the haupt case)

 

[Morninggloryseed]

Just some artwork.

 

[psykap]

The Azo , These are individual differences , for example I have friend who 2C-P loads about 30-1h oral. (incredible? I have to wait 3-4 h for peak)
I wrote this note under the influence substance and I got impression that duration is the same like with 2C-P , something about 10-15 h , Next day I was feeling washed mentally , I have also little troubles with muscles at this dose . They were very tense but another negative effects I havent noticed.

Pitaburd it isnt similar to 2C-P When I took first 10 mg , the experience was similar to 2C-E But when I am tried higher dose the substane shows me that it is quite something new , If someone ask me to compare to something it would be a few 2C-E and a few 2C-I
There is no sens in comparing 2C-P with 2C-iP Its the same like comparing of 2C-B-FLY and 2C-B They have many different effects
2 days ago I am tried 35 mg , I think that it was my last test , but at this dose still I havent noticed strong OEV/CEV . I suppose that dose for 2C-iP is following

5-15 mg -Threeshold
15-25 mg- Light
25-35 mg - Common
35-50 mg - Strong

 

[porkstock]

...This might hinder the 5-methoxy from properly interacting with the neighboring serine's hydroxyl.

what is this serine residue you guys keep mentioning? is it part of the serotonin receptor?

 

[Astavats]

Yes, known specifically as Ser5.43(239). You can read more about the docking here; Towards a biophysical understanding of hallucinogen action.

 

[acidbaby]

This is quite a discrepancy!
Makes me question whether a vendor may be sending out something else as 2C-iP?

The lab that produces this does some experiments with 2 Carbon compounds. The bulk of their business is in making precursors. They do some contract work making PEA's that might be active for RC enthusiasts, hence 25C-NBOMe and 25D-NBOMe. They keep a lot of 2C-H on hand.

Frankly I wait for a few trip reports before I start fucking with this stuff. 25C-NBOMe is the most promising so far.