2,5-dimethoxy-4-bromobenzylamine

[Noooo]

If such a compound were to exist, would it likely be active? Would it's effects be similar to 2C-B? A benzylamine is basically a phenethylamine with the ethyl group replaced with a methyl group, right? Does the loss of that 1 carbon remove activity, or is it not very important?

I apologize if I'm wrong about all this, I'm fairly new to chemistry. I'm not actually planning on synthesizing this or anything, I just am trying to get a little better of an understanding of the chemistry of these substances.

 

[Limpet_Chicken]

More likely to be an MAOI, preferring, or selective for the type A isoform of monoamineoxidase (as an inhibitor), although benzylamine itself is metabolized by MAO-b.

 

[Noooo]

Huh, interesting. A couple more questions, if you'd be so kind: Would the isoindole equivalents of tryptamines likely be active? Also, would THIS be likely to be active? It's essentially DMT, but where it branches off the indole has another nitrogen instead of a carbon.

 

[Noooo]

Oh, and one more please: 1-methyl-3-amino-6-methoxy-7-bromobenzopyran? That should essentially be DOB, but with the alpha methyl group that makes it an amphetamine contorted to instead bond with the oxygen to make a second ring. Would it still be active?