1 week delayed comedown is it possible ?

[no_id]

Hi
I absurdely binged on 6apb for some days (hopefully without redosing at too small interval, was dosing 1 time a day 2 time the extra day ), from smth like friday to last tuesday (3th of feb) with skipping 1 day.
Knowing that i would go snowboarding the next week end with my parents, I was somewhat worried about getting a major comedown wich would ruin the w-e.

Finally, was somewhat trippy for wednesday, down for tuesday and somewhat ok for the rest of the week, if a bit off and anxious (plus classical lack-of-serotonin induced waking dreams/sleep paralysis - Im used to this, Im sometime subject to them even without being in a comedown), but in a functionnal mood.

Trying to get rid of a hypotetical wrong future state of mind and/or to maintain mood in ok state Ive done other not recommended stuff like consuming 200mg tramadol on wednesday, 100mg 2fa tuesday, perhaps more tram on friday dont remember, and another 100mg 2fa saturday morning (im in the process of kicking a speed addiction, Im tapering off proggressively using less and less each 2 days, probably will stop at the end of this week).

But today (6 days after last 6apb consumption) I experienced a major crash with dizziness, anxiety and depression, feeling out of it, memory feeling fucked (perhaps due to speed withdrawal - as one is far more confident in his mental ability while on speed so i bet it s the contrary while on withdrawals), and other feeling wich left me almost unable to work (computerscience).
Im better now (but still not right), was able to smoke without anxiety (didn t smoke for approx 1 month), but I fear it will be the same funk tomorrow (without speaking about the fear induced by all long term comedown post).

Is it possible to get a comedown from empathogen almost 1 week after use ? Or these feeling was from smth other than 6apb ? Knowing that I indulged in serotonin modulating drugs for 4 days after last 6apb day (tram and 2fa) wich is perhaps a reason for the delay...
Ill probably skip the next 2fa dose (60mg was planned this wednesday), do you think ill be ok for tuesday of this week (I go back snowboarding) ? Are these symptom more characteristic of a comedown or a LTC (I admit Im somewhat worried about that) ?


Not to mention ill never take that shit again, as every other fucking stim when Ill be completely off them, I stick now with acid/shrooms/weed. More fun and I gain lot more from them.

Sorry in advance for probable english mistake, Im french

Edit : interestingly my current state is not so different than the day after a 100/200mg MXE session when I was into dissociative at the begginning of the last year. Same physical feeling, like skin feeling a bit numb, same off balance feeling, same if not more brain dead feeling. This state never happened after Ketamine use, this left me think that it was the serotonergic effect of mxe wich was responsible of this state (and that its serotonergic property is not negligible).

 

[terarc]

Personally I think a comedown 1 week later IS the comedown. That's when my mood is lowest after MDMA, and I use usually once a month for 3-4 months, and then take a 6 month break.

I personally think when you take MDMA, if you have not abused it, your serotonin is raised for a few days following, and then that excess serotonin is removed by enzymatic degradation or reuptake. Now for the next few days, you should be OK, if a little below your serotonin levels before your dose, as your brain will still have adequate levels of serotonin (assuming still you've not abused it), but over this time, the reduced amount of tryptophan hydroxylase enzyzmes (caused by MDMA, probably a metabolite of it and not directly by the drug), causes you not to be able to generate enough serotonin from the tryptophan in your diet, resulting in a low mood, around 1 week after you dosed! Though I think on your first few times, you don't get a comedown at all simply because your brain is still so fresh to drug, no serotonin deficit at all, no 5-HT downregulation, etc... you've essentially had your entire life 'break' to build serotonin

Now if you've abused it, your brain was struggling with serotonin to begin with, and so when the excess is removed after 2-3 days, you feel down at that point as your brain has gone from >struggling with serotonin< to >struggling even more with serotonin< and you feel the comedown after those 2-3 days ("suicide tuesday"), and probably start feeling a little better after that because your brain is already in panic mode to make more serotonin, whereas if you haven't abused it doesn't see the deficit as quite as significant.

Then finally I think if you're a REAL abuser, you get the comedown the next day (MDMA hangover), as you didn't even have enough serotonin for the MDMA to release in the first place.

Anyway that's just my opinion, based on a few various studies and write-ups of other people online. I think this kind of comedown is different to the "Long Term Comedown" people report for a long time after a period of MDMA abuse, which I think is more related to the down-regulation or damage to 5-HT neurons, making them less able to 'feel' your serotonin levels (and produce a normal, balanced mood etc). Obviously there may well be much more involved than what I've mentioned that we simply don't know the mechanism of yet.

Replace MDMA in my post with methylone/mephedrone/6-APB etc, same applies for all serotonin-releasing empathogen-entactogens

 

[no_id]

Interesting theory.
I don't remember having been affected this late with other serotonergic like 3mmc or m1, thought.

Anyway this night I managed to get good sleep after some good weed.
Today morning was feeling ok, I don't have much this off balance / 'off' feeling, waked and baked, absolutely don't want to work lol

 

[no_id]

So my post was useless, I'm okay now, was just worried about all the LTC stuff (never got dizziness like yesterday at this point before).
Anyway I'll probably skip 2fa tomorrow, as I don't feel the need for it now plus tomorrow I dose acid or 4hoMET I don't want to waste the trip

 

[BlueBull]

Nice to hear. Next time don't panic, those LTC stories you read are pretty rare if you look at how many people use MDMA and the way most of them are using it. MDMA can have some pretty wacky after-effects if you dose too high, combine with other drugs or roll too frequently but they are almost always short-term. I would still wait a while before you use any drugs though, give your body ample time to fully recover. Did you test your drugs with a testkit by the way?

 

[Deleted member 337748]

ltc are usually from semi long term abuse like a binge and i usually get delayed comedowns from beast mode abuse.

cause and effect