metaomega:really?A bit a surprise to me as the pyrrolidines are usually active.At least the title compound 1-{1-(3-Methoxiphenyl)-cyclohexyl}-piperidin has valid binding data out there,as does its OH cousin which has yet to be tried in humans.
Thats about the logic I used in the first place; 3-OH shown to increase potency, the pyrro for the piper swap shown to increase potency, so it should be potent, more potent than regular PCP. Unfortunately as I learned this isnt like 4-anilidopiperidine SAR where things usually do work literally that simply, for PCP analogs its a whole different mixed-bag SAR. It didint pan out the way I had hoped. Even when marijuana was combined with it there was no effect apart from the MJ, and marijuana seriously potentiates the intoxication from regular PCP in my experiences. Im not sure what happened in the SAR that led to this being seemingly inactive, it couldve been active in a ketamine dose-range, I never got that high as it kinda got eerie that the SAR hadnt panned out at all the way I had intended so who knows what its really doing to the neurons, and it clearly wasnt more potent than PCP so the primary goal failed anyways.
PCPs a pretty beautiful molecule though, its quiet simple to produce in a clandestine facility and it seems it can be simply modded to yield a wide range of differing core pharmacologies, its like a cube that can morph into a circle or a triangle too, now thats a useful cube.
Not to wander off the original topic, but I rarely see serious PCP discussion threads so I must, has ANYONE yet tried BTCP? If it wasnt for the fact catalogs offering it want rediculous prices paid for rediculously small quantities, I probably wouldve tried this by now. It SOUNDS like a very interesting stimulant, but is it strictly dopaminergic or is it an SNDRI like cocaine? I only recall rearing about its dopaminergic activity. Also does anyone have a ballpark of what they think the RED (recreationally effective dosage) of this is gonna be (or IS if they tried it)?