β-CFT naphthalenedisulfonate (WIN 35428)

[krissilasn]

Has anyone here on bluelight heard much about this Cocaine analogue?

I recently stumbled across a source and was wondering if any human use of it has been documented...

 

[Slapdragonx]

β-CFT is illegal in the US (Schedule 2) and is also controlled in the Germany.

More potent and lasts longer. β-CFT binds to the DAT at 30nM versus cocaine at 230nM.

The maximum cocaine substitution of β-CFT is 99.9% give/take 0.1. (Cocaine oddly enough was only rated at 99.7% give/take 0.3)

Loland CJ, Desai RI, Zou MF, Cao J, Grundt P, Gerstbrein K, Sitte HH, Newman
AH, Katz JL, Gether U. Relationship between conformational changes in the
dopamine transporter and cocaine-like subjective effects of uptake inhibitors.
Mol Pharmacol. 2008 Mar;73(3):813-23. Epub 2007 Oct 31. PubMed PMID: 17978168

The reference is free via Pubmed.

For the table of affinities:

http://molpharm.aspetjournals.org/content/73/3/813/T1.expansion.html

For the discrimination rate (basically the amount of time it substitutes for cocaine):

http://molpharm.aspetjournals.org/content/73/3/813/F6.large.jpg

 

[lostinshell]

is it anesthetic too?

 

[Hammilton]

It lacks the benzoyl group, which I believe is necessary. Someone else can confirm or refute this, though.

 

[atara]

Schedule 2? For such an unknown compound?

 

[C_Tripper]

I do believe I have this chemical compound in my posession. It's a very interesting drug. Not very much in the way of numbing. I am sending it away to get tested, find out what it actually is, but anecdotally it fits the exact profile. Goes and goes too!

 

[muzzard]

I do believe I have this chemical compound in my posession. It's a very interesting drug. Not very much in the way of numbing. I am sending it away to get tested, find out what it actually is, but anecdotally it fits the exact profile. Goes and goes too!

tr plz

 

[SKL]

Trip report: β-CFT (WIN 35,428) 7 mg, i.v.