Search results for query: psilocybin

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  1. Esperighanto

    RCs Do any good legal highs still exist ??

    ...many cannabinoids and entheogens can be acquired too, as long as we're talking about the US. Mitragyna alkaloids, tianeptine, native things like amanitas, ephedra, harmala/tryptamine containing plants, psilocybin containing fungi and mescaline containing cacti are also obviously highly relevant.
  2. mr peabody

    CONSCIOUSNESS | +20 articles

    ...some way, there were large increases in attribution of consciousness to a range of animate and inanimate things. Psychedelic drugs like psilocybin, an ingredient found in so-called magic mushrooms, have shown promise in treating a range of addictions and mental health disorders. Yet, there’s...
  3. xdrc

    Tryptamines Matoprolol with heroic dose of mushrooms.

    Was this from personal communication or can one read more about this somewhere?
  4. red22

    Heim 1968

    ...was increasingly reduced, as compared to placebo subjects, during the time of observation. This is in contrast to observations on Psilocybin: here the psychometric results were worst after the first 45-min-phase, whereas changes in expression and motor behavior were greatest in the last of...
  5. red22

    Phenethylamines Using mescaline as a substitute for DMT in ayahuasca

    i’ve tried this combination and it had no real overlap, they dont potentiate each other. 2c-b is only potentiated by mao-B inhibitors (see the mescaline page on wikipedia), so not that much point to it The fear over this combination is overexaggerated especially in the case of small doses...
  6. red22

    Pharmacology Does JRT get its nootropic effect from tryptamine?

    ...resulting in a compound that retains neuroplastic effects while minimizing hallucinogenic properties." Sounds like a cross between psilocybin and lsd Exactly—that’s a pretty good intuition. 😄 Structurally and pharmacologically, JRT does resemble a hybrid of LSD and psilocybin in a...
  7. Esperighanto

    Requests Thoughts about Metocin 4-HO-MET ?

    ...whatsoever. The visuals are sort of "cartoonish" and "artificial" seeming to me, in a way that's more similar to 25B-NBOMe/25B-NBOH/Psilocybin containing fungi than it is to any other psychedelic, at least for me. Therapeutically I consider metocin virtually useless, though in combination...
  8. O

    Positive On a positive note.....synthetic psilocybin-Metocin

    I can without a shadow of a doubt share your experience of psilocybin being the medicine needed to get out of a med-withdrawl -paws- any depressed shit that leads me backwards, was erased. I think it sustains because you integrate the experience and also preparing for the next, is HIGHLY...
  9. red22

    Lysergamides LSI, Ancient LSD, Secret of the Eleusis Kykeon and Vedic SOMA

    ...1.5 mg ergonovine base, ingested in a glass of water. 13.00 h: slight nausea, same effect as I have experienced always in my LSD or psilocybin experiments. Tired, need to lie down. With eyes closed colored figures. 13.30 h: the trees in the nearby forest seem to live, their branches moving...
  10. perpetualdawn

    Nootropics which psychedelic would induce the most neuroplasticity?

    ...from psychedelics claim is clinically well observed and measured now, I wouldn't say it's vague or inconclusive any more. "Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo" https://pubmed.ncbi.nlm.nih.gov/34228959/ "Psilocybin desynchronizes the...
  11. SuperPsych

    Tryptamines The Big & Dandy 4-HO-MiPT Thread - 2nd MiPteration

    I agree with 4-HO-MIPT being on par with psilocybin in terms of introspection. They both tend to focus on different things and they go about it differently. 4-HO-MIPT is pretty interesting in the fact that even when the introspection gets a bit intensive, the vibe still remains positive; whereas...
  12. 4DQSAR

    Nootropics Mushroom Gummies

    https://www.theguardian.com/science/2026/may/05/magic-mushrooms-psychedelic-changes-brain-anatomy-psilocybin I thought this might interest you. Sadly, @fastandbulbous appears to be MIA but they made quite an interesting point in that such fungi convert tryptophan into 4-OH N,N-DMT (psilocin)...
  13. M!$TER-ED

    Positive On a positive note.....synthetic psilocybin-Metocin

    I appreciate your response. I don't know how popular Metocin is globally, but I advocate for it in my trusted circles.
  14. SotPoker1012

    Nootropics which psychedelic would induce the most neuroplasticity?

    ...is that sigma might be why DMT produces rapid antidepressant effects in some people - though many of the same people respond well to psilocybin which is weaker at the sigma receptors so 5ht2a activation is probably still the main effect. As well as whatever downstream effects activation of...
  15. emkee_reinvented

    Bluelighter's guide to soul food - What is the best thing to eat when you're high?

    ...totally. Mine uses minimal. But a time effort and setting the clock. And working with string s under influence of psychedelic s not advised for beginner s. Not that i am, atm, just imagining. Squeezing Orange s not something to underestimate or take lightly. On Psilocybine containing mushrooms.
  16. Juicewrldfan

    Ethnobotanicals Psilocybin, synthetic and BUSPIRONE safe?

    Is it safe to take psilocybin synthetic with Bruce Brown already in your system taking this morning 10 mg
  17. F

    RCs Do any good legal highs still exist ??

    I hate bad the scamming has gotten you dont know if your getting the chemical you paid for you almost have to test everything to make sure.
  18. pupnik

    Nootropics which psychedelic would induce the most neuroplasticity?

    ...rather than what we sustain later in life when we enjoy psychedelics. Among Psychedelics, the salvia divinorum path to strangeness is quite extreme, although psilocybin and LSD are sufficiently strange to produce altered mental formations, and neuroplastic muchness however you interpret that.
  19. C

    CHRONIC PAIN | +80 articles

    ...more anxiety and pain by virtue of that consistency. Alcohol is nasty stuff, must be why I like it). I'm very curious about using psilocybin in this way but I think maybe I should wait a month or more until my neurotransmitters are better reset from the alcohol. Anyhow, that's my plan! 9...
  20. TheLightBringer

    Tryptamines Mushroom mini-sessions and microdoses

    Yes the dosage is quite different in psilocybin and MDMA which does give me hope, Im unsure of the safety profile of 2C-B regarding 5HT2B agonism. Other phenethylamines do posses quite the affinity for 5HT2B. I think everyone should be aware that Alexander Shulgin who trialed many tryptamines...
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