Search results for query: SSRI and cocaine

Wow, anhedonia is quite a severe symptom. More than just hormonal going on with all of these symptoms. r/depressionregimens, r/MAOIs, r/anhedonia Anyways, there are a few things that work for anhedonia. May wanna consult Dr. Ken Gillman or email him. Ketamine IVs, TCA, MAOI are the main meds...

Bro lice two decades ago I was in a 100% psychotic alternate reality version of the world and my life. For two weeks :P My mix was Tramadol, xanax, weed and the tiny little powerful spark to egnite the most bizarre experience I would ever have in my life. Ive done all of the psychs. not just...

100% agreed! There are some small studies showing efficacy of Buproprion (atypical SSRI, cathinone) or NAC. Don't know about Baclofen from my own experience. Pregabalin and F-Phenibut have helped myself with quitting stims. Be careful though not to trade the cocaine habit for another compound...

Yah man, I agree with the Paxil guy, an ssri might really help you, then you could slowly wean off of it. I know you said weed made things worse, but have you tried high CBC low THC weed? I’d recommend something with 5% or less THC, and 15% or more cbd. Maybe gabapentin, kava kava, black seed...

Cocaine is some sort of SSRI or SRI, so it actually cancels out MDMA. Couple that with the rapid hardbeat, sweating and totally different vibe. Not a nice combo. Cocaine after coming down of MDMA did work. Opposed to coming down of Amphetamine which makes MDMA shine. Couch lock shine with...

Just some of my personal experiences (inc. rx stuff that I didn't abuse/isn't recreational) SSRI - Sertraline (Zoloft) - found is VERY hard to cum for 2-3 weeks, like took forever and really had to fantasize a lot. After that it was harder than usual to come for some months, then gradually...

Age 16 - alcohol Age 17 - DXM, psilocybin, weed, SSRI (prescribed), ephedrine Age 19 - mephedrone Age 20 - dexamphetamine and methylphenidate (prescribed) Age 22 - methoxetamine, alpha-PVP, RTI-111 and other RCs Age 24 - buprenorphine, methadone Age 26 - cocaine, 4,4'-dimethylaminorex Age 29 -...

I never said a full blown-up roll. However, my physiology is such that I get major euphoria and horniness from SSRI's at normal doses. So yeah, 25-30 mg of sass or 5/6-APB DEFINITELY elevates me. It's above the threshold dose for regular people anyway. I've probably been rolling before you...

Everyone is different for sure. Im going back to zoloft after trying it before. Ive done prozac, lexapro, cymbalta and wellbutrin. Wellbutrin is the only one id never drink on again. Ssri’s you can drink on.i hate not being able to finish sexually easy on ssri’s… thats my main gripe with them...

I always wondered how much of the "magic" that coke inherits stems from it's effects on serotonine? (never tried real coke but read experiences). Pure stimulants like phenidates and pyrovalerones that are often compared to coke usually have more or less only effects on dopamine and...

Coke and methylphenidate are inverse agonists at the transporters, causing them to dump their targets instead of sucking them up. That's why cocaine has such pronounced acute effects and a SSRI doesn't. Because with a plain transporter antagonist autoreceptors immediately downregulate release of...

My lack of further experience with pure harmaline derives from my having been engaged, since the time of the above research, in the study of harmaline combinations: harmaline-MDA, harmaline-TMA[1], harmaline-mescaline and others. [1] TMA: trimethoxyamphetamine. The Healing Journey: New...

Fact is imo, that morphine and other opioids wouldn't get approved as of today if they weren't already. The approval process changed drastically during the last few decades. Stuff like DXM and even amphetamine got easily approved and sold in the 19xx's. I think you could buy fucking cocaine in...

Be careful when using high purity cocaine while also taking risperidone + flouxetine this could easily lead to serotonin syndrome the beginnings of serotonin syndrome might initially be mistaken for the effects of cocaine, watch out of that (ritalin also increases serotonin) I would highly...

I disagree in one aspect. The only opioid that stopped helping my depression in the long run was buprenorphine. Yet even after 7 years, it still helps to a slight degree to keep me from un-aliving myself some days. Where as normally I would be ready to die 24/7. Yet I never had that issue on...

I don't know if this is a clue but in 'The Case of the Frozen Addicts' the very first victim had produced an opioid that had MPTP as a major impurity. He was given L-DOPA to treat his symptoms but apparently 'abused his medication' until doctors switched him to something else. Apparently he...

Stimulants can indeed have antidepressive and even anxiolytic effects in therapeutic effects. Sometimes is less more, and one has to be aware that stimulants can be very addictive and lead to compulsive and manic behaviour. This risk increases with the dose. I would recommend dextroamphetamine...

You mentioned that you are also taking Diazepam and buprenorphine yes? I would first of all say that mix does not give good thoughts (I am also on opioids, benzos, Pregabalin, Amitrityline and an SSRI antidepressant daily, plus cocaine thrown on top) So, I would suggest that the addiction is in...

hi. i just read your post and feel ive walked in the hell of your shoes. i'll fast forward to what my current psych wants to do. after 40 yrs of ssri's, he wants to switch to maoi's after two wks cleaning me on tricyclics. also, i'd be doing tms and esketamine - Spravato - at his office. i...

Yeah that makes sense. Methylphenidate and cocaine both work as dopamine and norepinephrine reuptake inhibitors. Cocaine also acts as a serotonin reuptake inhibitor as well, something missing from Ritalin’s neurotransmitter profile, as it were. And it’s for this reason that doing cocaine whilst...