He has some diazaeam tolerance so that will create cross tolerance
no real need to push the diazepam that high, he's on 5mg a day, 20mg is a big jump. 5mg is fine with 1 soma.
had similar issues and had a problem with Soma over a couple of years.
I think partly this is not eating on a truly empty stomach, and I think the consistency of dosage per pill of the indian generics is piss poor.
Also Carisoprodol is metabolised by the CYP2C19 enzyme, CYP2C19
He has some diazaeam tolerance so that will create cross tolerance
no real need to push the diazepam that high, he's on 5mg a day, 20mg is a big jump. 5mg is fine with 1 soma.
had similar issues and had a problem with Soma over a couple of years.
I think partly this is not eating on a truly empty stomach, and I think the consistency of dosage per pill of the indian generics is piss poor.
Also Carisoprodol is metabolised by the CYP2C19 enzyme, CYP2C19 levels can be effected by quite a wide range of things meaning a person might just not metabolise as fast on different days - not looked into this in detail to understand how big an effect this has, but combining the 3 things could explain the inconsistency.
I always find the best results by dissolving in warm water and swallowing on an empty stomach (pre-breakfast is best) - fastest most consistent on set that way for me
not condoning it, but 1 of the reasons is that Meprobamate is meant to potentiate the opioid (though I thought it was more additive than potentiating the opioid directly).
agree on the black out
levels can be effected by quite a wide range of things meaning a person might just not metabolise as fast on different days - not looked into this in detail to understand how big an effect this has, but combining the 3 things could explain the inconsistency.
I always find the best results by dissolving in warm water and swallowing on an empty stomach (pre-breakfast is best) - fastest most consistent on set that way for me
not condoning it, but 1 of the reasons is that Meprobamate is meant to potentiate the opioid (though I thought it was more additive than potentiating the opioid directly).
agree on the black out