Gabapentinoids Na GHB dosage?

[Didgital]

I'm a little confused on this substance.

What is a typical dose for the sodium salt of GHB as a powder.

It's annoying that people talk about dosing it in a liquid form when the pure compound is a solid. Is 2.5g a reasonable dose?

Also wondering like, how much salt is in say 100mL

 

[bornabuser]

https://erowid.org/chemicals/ghb/ghb_dose.shtml

But better to be on the lower side than do too much lol

 

[Didgital]

https://erowid.org/chemicals/ghb/ghb_dose.shtml

But better to be on the lower side than do too much lol

that was the first place i checked, but it says pure GHB and I'm asking about the sodium salt form.

 

[bornabuser]

Would that be like sodium oxybate used for medicinal purposes? Was hard to find any info regarding recreational dosages, the information seemed to be strictly for it's intended use, and the dosages seem to be higher than for pure ghb, like roughly twice as much for therapeutic use compared to pure GHB dose for recreational use. But it seems very sketchy to try to calculate a dose based of this.

 

[placebonaut]

It's annoying that people talk about dosing it in a liquid form when the pure compound is a solid. Is 2.5g a reasonable dose?

it's mostly liquid in Europe from what I've seen.

Drug.Community

Drug.Community is a harm-reduction encyclopedia of psychoactive substances, subjective effects, and experience data.

substance.wiki

this says it's for sodium, 2-5g is a strong dose - 5g seems too high to me personally

GHB - dose.wiki

GHB is a depressant that occurs naturally in the human body. First synthesized in the 1920s, it has seen varied use as an anesthetic, a bodybuilding supplement, and eventually...

dose.wiki

2.5g-3.5 for strong

It's been a long time since I've looked at this because of the lack of powder in europe, but I have in my head that gram to ml equivalent wasn't too far away from being 1:1, so this seems a high dose to me personally, IIRC I was taking 2ml GHB for quite a strong effect - but I'm going from memory.

Better advice would be to start lower, like 1.5g and titrate up the next time, or if you can't wait start lower with a view to redosing after an hour. I generally redose after 1-1.5 hours at about 50% my initial dose, so if you're initial dose is too light you could maybe increase this to 60-75% maybe. Keep track of your total in a session and try to keep it at a sensible number if you're redosing (not gonna advise on numbers because YMMV but once you find your initial level 2-3 times your total initial dose is where I find I can start nodding depending on how quickly I'm taking it) - if you start feeling the nod you're pushing it too far, but if you're taking it slowly that should be an early warning sign rather than a sign you're already in too deep and about to G out. Stay safe!

Outta interest I have it in my head that sodium and potassium are slightly different in strength, but I just had a search and can't find out if I'm remembering correctly.

 

[Didgital]

I have in my head that gram to ml equivalent wasn't too far away from being 1:1

I did a lot of reading and spoke with some homies about the subject after making my post/comments. I think you are pretty spot on. I've read that when consumer gets the product they "test" for quality based on density, which should come out at 1.2-1.2g/mL At that optimal concentration, each mL contains about .5g so a 1:1 sounds about right that would put 2mL = 1g which I would call a lighter dose.

The potassium ion is heavier than the sodium ion so K-GBH salt is going to be less GHB than the Na-GHB salt per gram. 1g of Na-GHB is 819mg of GHB while 1g of K-GHB is 725mg. There's also probably differences in solubility so you might be able to get more Na-GHB into solution than K-GHB. I really don't know though.

 

[placebonaut]

The potassium ion is heavier than the sodium ion so K-GBH salt is going to be less GHB than the Na-GHB salt per gram. 1g of Na-GHB is 819mg of GHB while 1g of K-GHB is 725mg. There's also probably differences in solubility so you might be able to get more Na-GHB into solution than K-GHB. I really don't know though.

makes sense in terms of why, not sure what this equates to in terms of changing dosing even though there's an implied ratio here, just a call out to future readers of this thread that you need to check this if you're taking the potassium K-GHB version, or be safe and practice good HR by starting low and titrating up etc etc.

now I've slept on it, I also think there was a lot of discussion on reduction of sodium intake as a driver to move to potassium, this was when I was looking at stove top GBL conversion to GHB for personal use. Ended up deciding it wasn't worth the effort given how infrequently I take GBL though

 

[GeorgiaHomegirlsBaby]

Would that be like sodium oxybate used for medicinal purposes? Was hard to find any info regarding recreational dosages, the information seemed to be strictly for it's intended use, and the dosages seem to be higher than for pure ghb, like roughly twice as much for therapeutic use compared to pure GHB dose for recreational use. But it seems very sketchy to try to calculate a dose based of this.

I take the prescription Xywav. It comes 0.5g/ml. My Rx is 4.5g twice nightly. So you're saying my medicinal 9g would be 4.5g recreationally, basically because pure is missing all the other stuff like calcium, potassium, etc?

 

[bornabuser]

I take the prescription Xywav. It comes 0.5g/ml. My Rx is 4.5g twice nightly. So you're saying my medicinal 9g would be 4.5g recreationally, basically because pure is missing all the other stuff like calcium, potassium, etc?

My chemistry knowledge is severly lacking to make any bold answer to this. Tried to find some information on this but medical sources and recreational sources seem to have some conflicting information which I can't make sense of as I lack the competence in this field. So don't take my post as gospel, considering the steep response curve of the drug in question.

 

[RUC4]

a clarification for future readers: ...there isn't a “medicinal dose divided by two = recreational dose” rule. Xywav's labeled strength refers to total oxybate salts, and a prescribed nightly total split into separate doses isn't comparable to one dose taken at once. please don't change your prescription based on this thread—check with your pharmacist or prescriber.

also, grams and milliliters aren't interchangeable without a verified concentration. please don't rely on nodding as a safe warning that you still have time before an overdose.

 

[placebonaut]

please don't rely on nodding as a safe warning that you still have time before an overdose.

spot on 100%, nodding out can quite easliy be a a critical emergency, it's not something that you should use as a safe warning.

Just for clarity having reread my earlier post, the point I was trying to make on nodding so it's clear, the total amount of GHB taken in a session when you are redosing is a factor for nodding out as well as each dose taken, GHB will build in your system given half life. Redosing too frequently is a CNS risk, redosing too many times is a CNS risk, redosing too high amount is a CNS risk, taking too much in a single session is a CNS risk, taking too high an inital dose is a CNS risk.....

If you're following good HR practice, dosage and titrating up you can STILL find you have taken too much in a session causing you to nod out because you've redosed too many times and/or redosed too quickly, in that specific situation the nod is a sign to STOP redosing - there's a difference here from a warning sign & minor nod when trying to practice "good" HR because you're "just over the limit" (we all get it wrong at times) versus having taken too much and Ging out versus taking far too much and being in serious danger. Important you know the differences and are educated!

Don't redose ideally, but if you must, limit your redosing to 50% of inital dose, try not to redose more than twice, and ensure your redoses are more than 1 hour apart (ideally 1.5 hours).

These are practical pointers because people are greedy and get carried away, titratation is best practice, there's always another day that way.

 

[RUC4]

spot on 100%, nodding out can quite easliy be a a critical emergency, it's not something that you should use as a safe warning.

Just for clarity having reread my earlier post, the point I was trying to make on nodding so it's clear, the total amount of GHB taken in a session when you are redosing is a factor for nodding out as well as each dose taken, GHB will build in your system given half life. Redosing too frequently is a CNS risk, redosing too many times is a CNS risk, redosing too high amount is a CNS risk, taking too much in a single session is a CNS risk, taking too high an inital dose is a CNS risk.....

If you're following good HR practice, dosage and titrating up you can STILL find you have taken too much in a session causing you to nod out because you've redosed too many times and/or redosed too quickly, in that specific situation the nod is a sign to STOP redosing - there's a difference here from a warning sign & minor nod when trying to practice "good" HR because you're "just over the limit" (we all get it wrong at times) versus having taken too much and Ging out versus taking far too much and being in serious danger. Important you know the differences and are educated!

Don't redose ideally, but if you must, limit your redosing to 50% of inital dose, try not to redose more than twice, and ensure your redoses are more than 1 hour apart (ideally 1.5 hours).

These are practical pointers because people are greedy and get carried away, titratation is best practice, there's always another day that way.

amazing points here. i agree with all of this. HR is essential to avoid OD. staying alive is most important, more than seeing how high you can get. we want you to stay around for the next high.