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Tramadol and alcohol

P

PollyPoll

Greenlighter
Joined
Jul 31, 2026
Messages
31
I'm looking for advice on drinking with tramadol. I got a box from a mate and I'm using them to supplement my dihyrdocodeine usage. I get DHC prescribed, and I'm using the tramadol to help cut down on the DHC from a much larger dose and to help save pills from my prescription.
I take two doses a day. Morning and dinner time. I've cut it down to Tramadol 100mg + 120mg dihyrdocodeine each dose, down from 10mg Oxy + 300mg DHC + 100 mg codeine cocktail each dose.

I've read all the caution of alcohol and tramadol for seizures etc. Do I realistically have to worry about that if I choose to have a few drinks tonight?
 
Any reason no one replies to my threads? This is i think the 3rd thread I've started and never get replied, yet see others starting threads every day and replied to within hours.... What's going on?
 
id say get deeper in the community by replying to threads before making too many threads
also please do not drink on tram its not a good idea and it wont be worth it
 
PollyPoll said:
I'm looking for advice on drinking with tramadol. I got a box from a mate and I'm using them to supplement my dihyrdocodeine usage. I get DHC prescribed, and I'm using the tramadol to help cut down on the DHC from a much larger dose and to help save pills from my prescription.
I take two doses a day. Morning and dinner time. I've cut it down to Tramadol 100mg + 120mg dihyrdocodeine each dose, down from 10mg Oxy + 300mg DHC + 100 mg codeine cocktail each dose.

I've read all the caution of alcohol and tramadol for seizures etc. Do I realistically have to worry about that if I choose to have a few drinks tonight?
Click to expand...
With a very strong disclaimer that I’m not giving medical advice here I can add that I have had a glass of wine in the evening a handful of times after taking up to 150 mg tram in the morning. Only in retrospect did it occur to me that this was not recommended. I have never heard that seizures were an issue in this context. Google told me to be concerned about excessive depressive effect along the lines of an opioid overdose. For me personally the serotonergic effects of tram are much stronger that its sedative effects. Maybe it’s more dangerous if the opiate-like effects are stronger for you. Or maybe I would have a higher seizure risk than someone who reacts differently. In any case I would never go beyond that single glsss of wine.
 
PollyPoll said:
I'm looking for advice on drinking with tramadol. I got a box from a mate and I'm using them to supplement my dihyrdocodeine usage. I get DHC prescribed, and I'm using the tramadol to help cut down on the DHC from a much larger dose and to help save pills from my prescription.
I take two doses a day. Morning and dinner time. I've cut it down to Tramadol 100mg + 120mg dihyrdocodeine each dose, down from 10mg Oxy + 300mg DHC + 100 mg codeine cocktail each dose.

I've read all the caution of alcohol and tramadol for seizures etc. Do I realistically have to worry about that if I choose to have a few drinks tonight?
Click to expand...

I'd ditch the Tramadol if I were you, it's a fake opioid.
 
I recently had a hypertensive crisis brought on by serotonin syndrome due to being prescribed tramadol after a dental extraction.

The SERT activation makes it much more risky than traditional opioids, especially if combined with other meds. Anything that enhances serotonin release can combine with tramadol in unpredictable ways. Dentist didn't check my med list, pharmacist didn't catch that a couple of the meds I take can increase serotonin release, and bam, I'm in the hospital with a blood pressure of 211/110 and altered mental status. The worst experience of my life is sitting in an ed bed, unable to speak clearly with my wife on one side and my mom on the other, both looking worried and trying to keep a good face for me.

I asked my dentist for hydrocodone, but because almost 20 years ago I was a heroin addict, something I am very up front and open about, she wanted to use something that was less "misusable". I don't like to get into power struggles around these things, so I went along with it. Still, if she'd gone with what I'd asked for and prescribed hydrocodone like I'd asked for, it would have saved a whole lot of worrying. As long as I've worked in health care as a clinician, and as much as I've been able to help prescribers understand the nuances of working with people who have used drugs, there is always going to be the presumption and stigma that comes along with their training.

Sorry, I know this isn't really what OP was asking about, but I have some pretty well-earned negative views of Tramadol's safety profile and wanted to give context.
 
tryptakid said:
I recently had a hypertensive crisis brought on by serotonin syndrome due to being prescribed tramadol after a dental extraction.

The SERT activation makes it much more risky than traditional opioids, especially if combined with other meds. Anything that enhances serotonin release can combine with tramadol in unpredictable ways. Dentist didn't check my med list, pharmacist didn't catch that a couple of the meds I take can increase serotonin release, and bam, I'm in the hospital with a blood pressure of 211/110 and altered mental status. The worst experience of my life is sitting in an ed bed, unable to speak clearly with my wife on one side and my mom on the other, both looking worried and trying to keep a good face for me.

I asked my dentist for hydrocodone, but because almost 20 years ago I was a heroin addict, something I am very up front and open about, she wanted to use something that was less "misusable". I don't like to get into power struggles around these things, so I went along with it. Still, if she'd gone with what I'd asked for and prescribed hydrocodone like I'd asked for, it would have saved a whole lot of worrying. As long as I've worked in health care as a clinician, and as much as I've been able to help prescribers understand the nuances of working with people who have used drugs, there is always going to be the presumption and stigma that comes along with their training.

Sorry, I know this isn't really what OP was asking about, but I have some pretty well-earned negative views of Tramadol's safety profile and wanted to give context.
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Doctors aren't as competent as you think. I'm glad your okay.
 
evo4ever said:
Doctors aren't as competent as you think. I'm glad your okay.
Click to expand...
I insisted on hydrocodone but she kept pushing back and saying 'tramadol' because I was a heroin addict 18 years ago - something I was totally open with her about. It frustrates me when I get treated differently for being honest, but it is what it is.

Either way, I had a follow-up this week and told her that tramadol caused me to go to the ER and for further work, I really insist that if I'm in pain she work with me instead of mistrusting me. She understood and agreed.

Yeah...it was scary as fuck.
 
tryptakid said:
I insisted on hydrocodone but she kept pushing back and saying 'tramadol' because I was a heroin addict 18 years ago - something I was totally open with her about. It frustrates me when I get treated differently for being honest, but it is what it is.

Either way, I had a follow-up this week and told her that tramadol caused me to go to the ER and for further work, I really insist that if I'm in pain she work with me instead of mistrusting me. She understood and agreed.

Yeah...it was scary as fuck.
Click to expand...

It's probably best to keep historic drug use to your self otherwise you could end up shooting your self in the foot as you've just learned.
 
evo4ever said:
It's probably best to keep historic drug use to your self otherwise you could end up shooting your self in the foot as you've just learned.
Click to expand...
Over the years it's actually not been an issue. My psychiatrist knows and I get prescribed dextro/desoxyn, gabapentin, zolpidem when I need it, xanax when I need it. My pcp has prescribed me hydrocodone, diazepam etc.

For the most part I've found that being up front and also being a stable working professional hasn't been an issue. But this is a new dentist and I'm in an area that was really hit had by opioids in the 2000s, so I wouldn't be surprised if there's more hesitancy here.
 
Doesn't alcohol have the potential of triggering seizures after binge drinking, especially during the hangover?
 
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