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  • BDD Moderators: notsmokeymcpot42088 |

Methamphetamine purification via distillation

I agree that with most drugs are smoked in their freebase form, such as dmt and coke. But they aren't water soluble and meth is. With my limited chemistry understanding that would make meth a salt not freebase. Is this not the case?
like the other user said, your crystalline meth is HCl salt, water soluble, whereas the free base is not water soluble. In fact if ya left meth crystals lying around in open air, the surrounding water vapor humidity would begin to slowly react with it, even in sun UV light. Whereas the salt is more stable transportable
Free base forms will degrade from UV light and air exposure much faster than the stable salt forms
Free base meth is liquid at room temp and must be hit with dry HCl gas to crystallize


edited: for clarity/correction
 
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If I do an acetone wash I allow the used solvent to dry on its own just to see what actually comes off of each wash.
I've never seen anything substantial washed off of crystal other than residual MA via wet acetone.
 
In the case of methamphetamine, this is incorrect.
:) i went deep diving diggin for the answer to this question and its a close apples oranges one too
you could be right in the end ill be honest



Methamphetamine Free Base vs. Methamphetamine HCl

The fundamental difference is that methamphetamine free base is a volatile molecular compound, while methamphetamine hydrochloride (HCl) is an ionic salt. That difference substantially affects how each responds to heat.

Methamphetamine free base has a reported normal boiling point of approximately 212 °C at atmospheric pressure. Boiling is a physical phase transition: the methamphetamine molecule can enter the vapor phase without inherently changing its chemical identity. This provides a pathway for vaporization that does not require breaking the molecule apart.

Methamphetamine HCl, by contrast, has a melting point of approximately 172–175 °C, but this is not a boiling or clean vaporization point. Because it is an ionic salt, its behavior upon further heating is more complicated and can involve chemical decomposition rather than simply boiling as an intact molecule.

One of the clearest demonstrations comes from Sato et al., who studied methamphetamine HCl pyrolysis. They found that above approximately 315 °C, N-demethylation occurred, producing amphetamine, a primary amine. In simplified structural terms:

Methamphetamine (secondary amine) --> N-demethylation --> amphetamine (primary amine)

This is a chemical transformation rather than merely a phase change. The same study also identified other pyrolysis chemistry, including formation of dimethylamphetamine and additional degradation products as thermal stress increased.

A later study by Ferus et al. found still more extensive thermal decomposition of methamphetamine HCl at higher temperatures, including methane, ethylene, HCN, CO, CO₂, methyl chloride, and toluene. Importantly, the authors specifically associated methyl chloride formation with the hydrochloride form.


Bottom line
The evidence supports a meaningful distinction: freebase has a physical-vaporization pathway because it is a volatile molecular compound, whereas methamphetamine HCl undergoes increasingly complex thermal chemistry as it is subjected to greater heat.

For HCl, the literature directly documents N-demethylation to amphetamine and other pyrolysis reactions. The hydrochloride form also produces chloromethane and other volatile decomposition products under sufficiently severe thermal conditions.

However, the evidence does not justify saying that freebase undergoes zero decomposition or that it has been quantitatively proven to produce fewer total decomposition products than HCl. The strongest scientifically supportable conclusion is that HCl has documented salt-specific decomposition pathways, while the cited studies do not provide an equivalent quantitative freebase-versus-HCl decomposition comparison.
 
:) i went deep diving diggin for the answer to this question and its a close apples oranges one too
you could be right in the end ill be honest



Methamphetamine Free Base vs. Methamphetamine HCl

The fundamental difference is that methamphetamine free base is a volatile molecular compound, while methamphetamine hydrochloride (HCl) is an ionic salt. That difference substantially affects how each responds to heat.

Methamphetamine free base has a reported normal boiling point of approximately 212 °C at atmospheric pressure. Boiling is a physical phase transition: the methamphetamine molecule can enter the vapor phase without inherently changing its chemical identity. This provides a pathway for vaporization that does not require breaking the molecule apart.

Methamphetamine HCl, by contrast, has a melting point of approximately 172–175 °C, but this is not a boiling or clean vaporization point. Because it is an ionic salt, its behavior upon further heating is more complicated and can involve chemical decomposition rather than simply boiling as an intact molecule.

One of the clearest demonstrations comes from Sato et al., who studied methamphetamine HCl pyrolysis. They found that above approximately 315 °C, N-demethylation occurred, producing amphetamine, a primary amine. In simplified structural terms:

Methamphetamine (secondary amine) --> N-demethylation --> amphetamine (primary amine)

This is a chemical transformation rather than merely a phase change. The same study also identified other pyrolysis chemistry, including formation of dimethylamphetamine and additional degradation products as thermal stress increased.

A later study by Ferus et al. found still more extensive thermal decomposition of methamphetamine HCl at higher temperatures, including methane, ethylene, HCN, CO, CO₂, methyl chloride, and toluene. Importantly, the authors specifically associated methyl chloride formation with the hydrochloride form.


Bottom line
The evidence supports a meaningful distinction: freebase has a physical-vaporization pathway because it is a volatile molecular compound, whereas methamphetamine HCl undergoes increasingly complex thermal chemistry as it is subjected to greater heat.

For HCl, the literature directly documents N-demethylation to amphetamine and other pyrolysis reactions. The hydrochloride form also produces chloromethane and other volatile decomposition products under sufficiently severe thermal conditions.

However, the evidence does not justify saying that freebase undergoes zero decomposition or that it has been quantitatively proven to produce fewer total decomposition products than HCl. The strongest scientifically supportable conclusion is that HCl has documented salt-specific decomposition pathways, while the cited studies do not provide an equivalent quantitative freebase-versus-HCl decomposition comparison.
Thought experiment: when you think about methamphetamine, do you picture a caustic oil or a crystalline product?

Have you ever heard of a dealer selling the freebase “for smoking”?

Not gonna lie, it looks like you are using an LLM to rationalize incorrect information.
 
Thought experiment: when you think about methamphetamine, do you picture a caustic oil or a crystalline product?

Have you ever heard of a dealer selling the freebase “for smoking”?

Not gonna lie, it looks like you are using an LLM to rationalize incorrect information.

only used Ai to summarize all the researchgate synopsis (i summarized it so that i wouldnt need quote entire links like i was doing since ALL of the papers seems to reference both those above mentioned "et al" articles

but Ai wouldnt ever give you a single summary like that first pass (you would need re-run the research through it - in fact i copied and pasted those articles and had 3 Ai review it on top of my own comments

of course ya say meth or coke we picture the salt form

my thing was you could be right, but more decomposition byproducts seem to form rather than nice boiled off meth base
im justifying myself based upon byproduct formations clean boils over clean decomposition
 
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