"People do report that Banisteriopsis caapi does have psychoactive properties in its own right." Erowid.
https://erowid.org/experiences/exp.php?ID=33549
"With the resurgence of research on psychedelics[13], the β-carbolines of
B. caapi have been considered to play a minor role in the overall pharmacology of ayahuasca preparations. However, this is probably a narrow view.
B. caapi is the common ingredient to all ayahuasca brews, and chemical analyses have shown that while the β-carbolines are present in all ayahuasca samples, this is not always the case for DMT[14, 15]. For instance, an ayahuasca sample from the Brazilian Church
União do Vegetal, a group known to regularly combine
B. caapi with
P. viridis in their ayahuasca, was found to contain no DMT at all[16].
13. Sessa, B. Shaping the renaissance of psychedelic research. Lancet Lond. Engl. 380, 200–201 (2012).
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14. Rivier, L. & Lindgren, J. E. ‘Ayahuasca’, the South American hallucinogenic drink: an ethnobotanical and chemical investigation. Econ. Bot. 26, 101–129 (1972).
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15. McKenna, D. J., Towers, G. H. & Abbott, F. Monoamine oxidase inhibitors in South American hallucinogenic plants: tryptamine and beta-carboline constituents of ayahuasca. J. Ethnopharmacol. 10, 195–223 (1984).
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16. Callaway, J. C. Various alkaloid profiles in decoctions of Banisteriopsis caapi. J. Psychoactive Drugs 37, 151–155 (2005).
Article CAS PubMed Google Scholar
Morales-García, J.A., de la Fuente Revenga, M., Alonso-Gil, S. et al. 2017. The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro . Sci Rep 7, 5309.
doi.org/10.1038/s41598-017-05407-9
Introduction
"This bias towards visions and DMT clashes with the ethnographical evidence of local use. The terms most widely used for the medicinal brew—ayahuasca (in Peru and Brazil) and yajé (in Colombia)—refer both to the vine and to the brew itself, whether or not it contains chacruna. Some ethnic groups only cook the vine, without any additives, like the Tucano Oriental, the Marubo, the Achuar and the Matsiguenga."
Carlos Suárez Álvarez. Why You Will Never Get a Traditional Ayahuasca Treatment. 2017-08-10.
chacruna.net/you-will-never-get-traditional-ayahuasca-treatment/
The Purge and the Visions