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Is once a month too much?

I don't think people saying 'well I'm fine' is of much value. Yes, case studies ARE evidence, but the lowest quality evidence. Survivorship bias ALWAYS exists around drug use because people who were harmed tend not to join a HR comminuty after the fact.

You need a large cohort size will always show ouliers for whom MDMA usse appears to produce no measurable ill effects.

I found this meta-analysis in Nature Psychopharmacology. You can download this. Meta-analysis from a high-impact journal A meta-anaysis of 23 human studies.

link.springer.com

MDMA use and neurocognition: a meta-analytic review - Psychopharmacology

Rationale To determine the association between MDMA misuse and neurocognition using meta-analysis. Objective Separate analyses were conducted based on two sets of inclusion/exclusion criteria. A relatively stringent set required that the subjects be matched on important moderator variables...
link.springer.com link.springer.com

Of course the problem with any human study is the ethics. You can't sacrifice people, section their brains and directly test for damage. So association is all you can realistically say. But those P values are quite small...
 
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Dezi Daddy said:
What are long term effects of taking molly once or twice a month ?
Out of curiosity, I never have a problem with depression or feeling drained afterwards like some people experience…..
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If You’re Rolling, You Will Need To Wait 3 To 4 Days Between Pills. Also, You Can Only Roll So Many Times. It’s A Once In A Lifetime Opportunity.
 
GanjaPadre/Pharmacologist said:
I agree with you about pressed pills having some shirty substances in them.

Do you use Molly weekly?

Have you tried 5MAPB?

5MAP is now my fave over MDMA.
- I don't like grinding my jaw on MDMA
- I don't have any paranoia with legal 5Map
- I can actually sleep a few hours before the sun comes up.
- I know what's in the 5MAP
- I can always take a Pseudophed or drink a Red Bull to take in the sunrise before bed.
- I don't feel Nearly as brain burnt with 5map
- I can get 5MAP for about half the price of MDMA.
- Too many pressed MDMA pills are speed bombs and keep me up for 2 or 3 days.
*I am not a meth person. In fact I am quite the opposite and enjoy my Indicas and Benzos.

After rolling hard I have a recovery kit. . .
After 24 hours from the last effects I use 5-HTP, Lemonbalm, Rhodilia, MCTs, {Mono-Chain-Triglycerides), like coconut or Avacado fats and oils. I drink many gatorades and juices and make sure to fuel up and then sleep.

I hope this helps and stay safe!
*Please rebuild some of your brain nutes with 5-HTP and Coconut oil.

Please make sure you're taking Molly and NOT some random crap in the pressies.
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I’ve tried the pills you’re talking about. I think 5-MAPB is superior, but some of what you’re reporting is pretty subjective, in my opinion. I also don’t believe they actually contain 25mg each.

I recently got 3.5g of 5-MAPB HCl. I’ve taken five of those tablets before, plus a redose of two more, and I’m skeptical that I actually took 175mg. We’ll see how the powder compares. I’m guessing that 70mg of the powder will absolutely floor me.

What I was getting at is that I expected 5-MAPB to cause more teeth grinding because it feels more serotonergic than MDMA, although I'm not sure if that's actually been demonstrated. I never really got paranoid on either one. Sleep is about the same for both. I usually need a benzo and my clonidine prescription to get to sleep once it’s over. I will say that it’s definitely 5-MAPB.

As for feeling burnt out the next day, there are a lot of factors involved. Redosing is a guaranteed way to feel like shit. I usually roll early in the morning so I can still get a good night's sleep afterward. It also helps to hydrate well the day before and get an adequate amount of sleep the night before.

I wonder when the tablets will get banned, lol. Luckily, I have 3.5 g of the powder, so I’m set for life. It’s much more enjoyable than MDMA, in my opinion. MDMA ends too quickly, and I’m usually left feeling sad afterward, whereas I find the comedown with 5-MAPB to be much more gradual. The stimulation doesn’t really matter to me, since I’m just as happy dancing as I am lying down on either one.
 
I did .4 a month and I never had more progress in my life. I got a job, I planned for a certificate for another trade job. I wanted a boyfriend. I was in the abyss of depression coming from schizophrenia my broken mind reassembled itself not because of this drug but to pay for it. God works in mysterious ways. It also helped to see the bliss possible. The month in between the doses were waves of progress. I don't know if this helps but it did me. But yeah you're fine.
 
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I'm curious as to how people can concluded if what they are actually consuming is MDMA (or homologue), an APB homologue or mixtures of two or more.

Because without instrumental analysis, how do you know?

With ALL of the APBs there is ALWAYS a mixture of positional isomers because Blanc chloromethylation is the first step in converting ACTUAL benzofuran to the IPA derivatives that are active. It's entirely possible to remove those positional isomers using preparative chromatography. But people accepted the impure product. So why would makers spend money and end up with less product?

I had to work out why 6APB & 5APB went from the hydrochloride salt to the inferior succinate salt. As it turned out it was because the impure product wouldn't turn into a nice white microcrystalline powder.

I'm not judging, just asking and giving my own experience of having to FIND the impurities.
 
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IME the long term effects of molly twice a month are largely it losing the 'magic' and becoming alot more like speed than an empathogen

Once a month even for me but I think do to other medications drugs that involve 'magic' are tougher for me than most ppl. I thought as my doses returned to normal my ability to regain said 'magic' would as well, no luck yet...

Haven't tried DMT though and that holds promise

^Marquis reagent test was as far as I ever went. When I got a G (smallest amount) it was usually one large greenish tinted crystal and it passed the marquis, purple if I recall and bk-mdma was yellow? , or maybe vice versa longshot neither and my memory sucks that bad.

.1 was fckin plenty and going to 150mg's even ya knew you were in for a ride. Only street mdma I ever believed was in fact MDMA -- hell I once had a kid say he had "Points of molly" I show up dude got crushed E pills in a baggie hes tryin to sell by the point...
 
just be responsible about it. test your stuff if you don't know it. and don't over do it. less frequency is preferred. but the human experience is much better with intoxicants.
 
crazyotter87 said:
I’ve tried the pills you’re talking about. I think 5-MAPB is superior, but some of what you’re reporting is pretty subjective, in my opinion. I also don’t believe they actually contain 25mg each.

I recently got 3.5g of 5-MAPB HCl. I’ve taken five of those tablets before, plus a redose of two more, and I’m skeptical that I actually took 175mg. We’ll see how the powder compares. I’m guessing that 70mg of the powder will absolutely floor me.

What I was getting at is that I expected 5-MAPB to cause more teeth grinding because it feels more serotonergic than MDMA, although I'm not sure if that's actually been demonstrated. I never really got paranoid on either one. Sleep is about the same for both. I usually need a benzo and my clonidine prescription to get to sleep once it’s over. I will say that it’s definitely 5-MAPB.

As for feeling burnt out the next day, there are a lot of factors involved. Redosing is a guaranteed way to feel like shit. I usually roll early in the morning so I can still get a good night's sleep afterward. It also helps to hydrate well the day before and get an adequate amount of sleep the night before.

I wonder when the tablets will get banned, lol. Luckily, I have 3.5 g of the powder, so I’m set for life. It’s much more enjoyable than MDMA, in my opinion. MDMA ends too quickly, and I’m usually left feeling sad afterward, whereas I find the comedown with 5-MAPB to be much more gradual. The stimulation doesn’t really matter to me, since I’m just as happy dancing as I am lying down on either one.
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US legal?
 
from my experience with mdma and mda:

when experimenting with this stuff, i took the MDA a couple months before the MDMA sessions. the MDA hit hard the first time. i only took half the pill. it was awesome.

three weeks later i took the other half of the MDA pill and it didn't work at all. felt literally nothing. i have no idea if all the MDA was in one half of the pill. probably not. this was high quality tested MDA from a source everyone loved.


like two months later, i have experience with a few MDMA sessions a couple months apart. i never got this stuff tested, but i tend to believe at least one of the sources was decent stuff. i took the amount my friends recommended to get a roll... i personally did not get very high off of any of the MDMA sesssions. the first one was a bit weak of a roll, and i had some alcohol in me, so that threw off the experience. the second experience about another month later with probably a good amount more of clean MDMA, i don't think i even rolled right from having a tolerance to the MDA and the first shitty MDMA pill that didn't really get me spun.


supposedly going from MDA to MDMA causes tolerance issues with the MDMA.... just want to say again i didn't have good luck rolling on the other half of my great quality pill three weeks later. the first time was a super intense experience. the MDA first experience made rolling a blunt like a salvia/dmt type trip with my eyes closed and when i was rolling the blunt in my hand, the visuals went along with the movement of my hands. it was awesome. i was super high for hours... nothing from the second try three weeks later.

keep in mind not everyone has the same tolerance to these drugs. i don't really get run down from taking them either. i really don't feel ill at all after the next day rolling if that means anything to you. i just have a long time for tolerance to drop...
 
It's a shame because para methyl aminorex is too serotonin selective so emotional warmth but very gentle. But meta methyl aminorex is more or less a pure dopamagenic.

We found a 2:1 ration of para/meta was certainly more MDMA than MDMA. More 'push' so sort of half way between MDA and MDMA.

But the idea of having to mix two raecemic ligands in one product was not considered safe. I know fastandbulbous was pretty sure 3,4-MDAR would be MDMA-like but as it turns out, for some reason someone went with the ring-substituted 4-methylaminorex and that has four stereoisomers and again, that seems too many things going on.

One day someone else will resolve AMT and note how different the two isomers really are. We know αET was misrepresened as MDMA and that in the Janssen patents, the 7-methyl derivatives were an order of magnitude more active than their parent. But AFAIK never tested in man.

But put simply, one isomer of αMT is your classic psychedelic, the other was surprisingly like MDMA. So I suspect the raecemic 7-methyl AMT would have the property of being an entactogen at a low dose with psychedelic activity at higher doses. A bit like MDA I suppose.

There are even other things that 'pack' that para & meta methyl into one scaffold such as desoxypipradrol (one ring para, the other meta) but again, you wind up with four stereoisomers.

I just think it's interesting that quite a few scaffolds do a pretty good impression of MDA/MDMA.

In the case of α-MT, resolution leaves no waste. It's simply two different products.
 
notsmokeymcpot42088 said:
US legal?
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Yeah, it's "legal." It's some smoke shop shit, just like 7-OH (RIP). I think they've had 4-HO-MET tablets available for quite a while now, probably a few years. The 5-MAPB tablets are a more recent addition. Obviously, sourcing isn't allowed, but I'd imagine you'll be able to find them pretty quickly. I'm glad I got 3.5g of raw powder, so the next time I do it, I'll know 100% how much I took. It's worthwhile if you enjoy MDMA.
 
Yea ill be able to find em quick if they 7 oh adjacent (RIP) I only got one box, knew I shoulda stocked up even though it isn't really up my alley right now.

I was aware of its existence but keeping track of what is legal and what isn't gets a little daunting sometimes.... I just figured they went illlegal when all the nbomes and the big blanket hit

Thank you for the info, knowledge is power and whatnot..... Haven't rolled or tripped in well over a year so this is a cool 'discovery'
 
notsmokeymcpot42088 said:
Yea ill be able to find em quick if they 7 oh adjacent (RIP) I only got one box, knew I shoulda stocked up even though it isn't really up my alley right now.

I was aware of its existence but keeping track of what is legal and what isn't gets a little daunting sometimes.... I just figured they went illlegal when all the nbomes and the big blanket hit

Thank you for the info, knowledge is power and whatnot..... Haven't rolled or tripped in well over a year so this is a cool 'discovery'
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Fa sho, there's an entire subreddit dedicated to it. It's the weirdest thing. I was looking for 5-MAPB powder for probably three years, and somehow I stumbled across that before I ever managed to source the powder.

I've mentioned it before, but I don't think the 5-MAPB tablets actually contain 25mg. They're probably underdosed, or I just love rolling too much. That last part is probably true.

P.S. Don't snort 2-MMC at 5pm on a work night. This shit sucks nasally. I feel like I'm having a heart attack right now. I have no idea how I managed to take 800mg orally over the course of a few hours on Sunday. It's a completely different high when snorted. I was wondering why people described it as "amph-like." Now I get it. This is nothing like the content, semi-rolly stimulation I had over the weekend, lol. I should've quit while I was ahead.
 
Borax Combo!

I'm saying we rejected because just FOUR discrete compounds were involved thus interaction hard to measure thus unsafe - here we see FIVE.

That is just crazy. If someone was taken ill, how many clinicians would even know where to begin...
 
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