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Misc Carisoprodol (Soma) ....thoughts & experiences ?

been taking a lot of soma over the past year and thought it was worth writing about my experience - keen to hear peoples thoughts and comments about it.

1st thing - it took me a long time to understand it, I didn't do my research correctly when I started taking it and didn't understand how it's converted into Meprobamate
2nd thing - Carisprodol causes the nod which can be defeated with a cuppa tea
3rd thing - weed and a glass of wine is it's friend
4th thing - the Meprobamate is the fun part
5th thing - it's innocuous, I started taking it as a muscle relaxer, that's not what it really is
6th thing - taking 1000mg 3-4 times a week is very easy, tolerance builds very quickly but also seems to reset very quickly (at least in me)
7th thing - Taurine potentiates Meprobamate for me - and it's even better
8th thing - I love it with Diazepam as well but that has all sorts of danger written all over it - I'm actively thinking how much I'd like that far more than I should
9th thing - I get anxiety rebound when I stop taking it....need to taper it but not sure how much by or how long for - advice greatly received
last thing - I'm trying to cut back and take it once a month max, right now I'm down to 2-3 times a week...crap

EDIT: bonus thing, don't swallow soma, subliminal is by far the best ROA, 2 under the tongue, let them slowly melt, hits harder and faster, but will make you nod, chase down with tea, mmmmm.
 
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Took 0NE once and had a paradoxical reaction where I had such extreme rage that my parents had to call paramedics to come sedate me and they had to inject me with 5mg Haldol and 5mg Lorazepam...and then another 5mg Lorazepam
 
ChemicallyEnhanced said:
Took 0NE once and had a paradoxical reaction where I had such extreme rage that my parents had to call paramedics to come sedate me and they had to inject me with 5mg Haldol and 5mg Lorazepam...and then another 5mg Lorazepam
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that's pretty much the opposite of any trip report I've ever read, you're allergic or something, clash with other meds?? sounds scary as fuck
 
placebonaut said:
that's pretty much the opposite of any trip report I've ever read, you're allergic or something, clash with other meds?? sounds scary as fuck
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Yeah, that's why I say "paradoxical" reaction as it's the opposite of the usual effects. Didn't clash with anything, I think the only other thing I'd taken was oxy and Soma generally goes very well with opioids.
Yeah, it was scary 'cause it was extremely out of character, too. Like, I'm generally a super-chill guy; it takes a lot to make me angry and with the Soma I couldn't stop screaming and ripped apart a chair and a table with my bare hands [and I'm TINY, like 5'5 and 104lbs].
It wasn't allergy; I didn't have any of that type of reaction, like no swelling, redness, itching, hives, wheezing etc.

Meds sometimes affect me weirdly. Ritalin makes me sleepy and opioids give me diarrhea.
 
Selection from "Modern Barbiturate Abuse". ASB. 2018-05-08. Erowid Experience Vaults. exp111872:

At 19 years old, I was so obsessed with sedative / anxiolytic RX drugs that I slept with a PDR next to my bed. I discovered that Soma (Carispodal) turned into meprobamate when it hit the liver. I had used Soma plenty of times over the years, and liked it, but found it to be an unreliable high. I wanted pure meprobamate, and found a doctor willing to prescribe it. She scripted me #30 400mg Equanil, a brand name for pure meprobamate. Once I felt the effects of meprobamate, I was off and running. I had found the drug that I always wanted, the feeling I always craved – numbness, and a complete lack of care, to the point that someone could be shot in front of me and I wouldn’t blink an eye.

EQUANIL (Meprobamate 400mg)
DOSE: 1200mg to 4600mg
EFFECTS: This is a very, very different drug than Soma (Carispodal) – much stronger, longer acting, and intense. Meprobamate is extremely pleasant, deadly, and as addictive as a ‘pure’ barbiturate. It starts to take effect about 30 mins after oral ingestion and is best taken on an empty stomach, though naïve users often get nauseous due to the dizziness.

The first effects are felt in the body – a tingling and numbness overcomes the body, and a jello-like feeling takes hold in my legs, making it hard to walk in a straight line. Numbness in the face is usually present, and is pleasant feeling. Dizziness is also present, and increases with the dose. A very ‘floaty’ feeling is felt, and laying down and doing nothing becomes ‘fun’.

Psychologically, meprobamate is similar to a ‘pure’ barbiturate. Euphoria starts to take hold as soon as the body high is felt. A feeling of calmness and carefreeness is felt, and increases with the dose. Loss of inhibition is felt. It is a very ‘social’ feeling drug – talkativeness is common, I personally always wanted to be around people when on this drug. It is more ‘social’ than barbiturates are, and has less loss of inhibition. Higher doses (1200mg and above) do produce a blackout, similar to that of alcohol or benzodiazepines, but more intense. Drinking on this drug makes it so that I am basically couch bound, and it can induce nausea and dizziness. Effects last for about 2 hours, and re-dosing is effective but less intense.

TOLERANCE / WITHDRAWAL: Tolerance gains rapidly, just as quickly as a barbiturate. Due to the fact that I was abusing the drug, I began to need higher doses in about a week. I personally ended up maxing out at around 4k to 4.6k mgs, and at that dose I was blacking out every time. This was my first withdrawal from a sedative other than a benzodiazepine, and it is much different than the latter. Meprobamate has a somewhat long half life, but withdrawal effects are felt sooner than the half life suggests. Symptoms include delirium, shaking, full on panic attacks that last all day, and strong derealization / depersonalization. I had to be medically withdrawn from Meprobamate, and even with the detox medications (which were at a higher doses than normal), negative effects could still be felt.

OVERALL: Meprobamate is basically a barbiturate, and has the same side effects and dangers as the barbiturate class of drugs. The high is somewhat more euphoric than Phenobarbital, but less pleasurable than other barbiturates. I would say the abuse potential is extremely high. Europe took all meprobamate substances off the market in 2012.
 
red22 said:
TOLERANCE / WITHDRAWAL: Tolerance gains rapidly, just as quickly as a barbiturate. Due to the fact that I was abusing the drug, I began to need higher doses in about a week. I personally ended up maxing out at around 4k to 4.6k mgs, and at that dose I was blacking out every time.
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my golden rule is never take Soma on consecutive days, I admit to taking it more often than I should do, but still don't notice the soma tolerance build, however I've not been as aware of Meprobamate upside and feeling until much later in my usage so not yet sure how quickly that builds in me and how fast tolerance resets.

now I better understand it I've starting 500mg redose once the Carisprodol has worn off as a way to boost the Meprobamate effects which when coupled with 1000mg of Taurine and cannabis is pure bliss

red22 said:
OVERALL: Meprobamate is basically a barbiturate, and has the same side effects and dangers as the barbiturate class of drugs. The high is somewhat more euphoric than Phenobarbital, but less pleasurable than other barbiturates. I would say the abuse potential is extremely high. Europe took all meprobamate substances off the market in 2012.
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pretty spot on! I'm loving the barb effect
 
I got this...scared the crap out of me.
I had 500mg tabs...one was good so I thought three would be better...I started to shake like mad could barly walk and even had trouble talking.

Do not take to much...for me 500mg was nice but more was not.
 
vision conquest said:
I got this...scared the crap out of me.
I had 500mg tabs...one was good so I thought three would be better...I started to shake like mad could barly walk and even had trouble talking.

Do not take to much...for me 500mg was nice but more was not.
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the soma shuffle

yeah important to titrate up, 1500mg in 1 go is a lot! 1000mg is quite a bit, would think for most 2x 350mg would be decent enough
 
I personally find it quite euphoric. Way more so than benzos. I think the American ones even rival opiates but that’s just me
 
(I'm not AI obsessed honestly, but it's my new toy! so take all this with a pinch of salt)

So I asked my sketchy AI that has the safeties removed how to improve Soma absorption and conversion to Meprobamate. I know an empty stomach helps a lot, but I've taken quite a lot sublingually which works very well but the binders tend to burn my mouth a bit so it's not ideal, I explicitly asked if the method below was better/faster than sublingual and AI thinks it's a superior method
  1. Crush and dissolve the Soma in warm water (40-50°C, 104–122°F)
    • Crushing the tablet and mixing it into water allows your body to absorb the drug immediately as it passes through the stomach
    • Warm liquids stay liquid longer in the stomach and do not constrict the stomach muscles. Cold liquids can cause the stomach to contract and slow down emptying
    • Hot Water (>70°C/160°F):* Carisoprodol tablets often contain binders (starch/cellulose). Hot water can gelatinize these binders, turning the mixture into a thick, gloopy paste that is hard to swallow and slow to digest
  2. 120-180ml (4-6 oz) for 500mg, 200-250ml (7–9 oz) for 1000-1500mg
  3. Take on an empty stomach
  4. Take with caffeine
    • Caffeine is known to speed up gastric emptying (the movement of food/liquid from the stomach to the small intestine)
  5. Take a CYP2C19 Inducer
    1. WARNING, CYP2C19 inducers can have interactions with other drugs either directly or because they also induce CYP2C9 & CYP3A4 which have interactions with other drugs. CYP3A4, CYP2C9, and CYP2C19 collectively process more than 60% of all clinically prescribed medications including Benzos, Antidepressants, statins - check for interactions with your meds
    2. Saint john's wort will work, but note you'd need to be taking this for ~14 days to have an effect
    3. There are other drugs which act as CYP2C19 Inducers, though they also generally also act on CYP3A4 and/or CYP2C9 as well
    4. 80-90% of Soma is typically metabolised into Meprobamate, using an inducer with both increase the speed of metabolisation and the % that is metabolised
Typical timeline
**15–30 minutes:** The warm liquid reaches your small intestine. Caffeine and warmth speed up gastric emptying, so it's on the faster end.
**30–60 minutes:** Peak levels of **Carisoprodol** in your bloodstream.
**60–90 minutes:** Peak levels of **Meprobamate** (after the liver converts it).
**Note:** You'll feel the initial effects within 15–20 minutes as absorption begins, but the full "hit" takes about an hour.

I'm giving this a go right now with 1500mg of Soma and can report success, onset for Meprobamate seems just as fast if not faster than sublingual, result!

Another cup of coffee on the go, some weed, and an omelette - breakfast of champs, at least the champs who like to chill the fuck out

I'm likely to redose another 500mg after 2-4 hours to keep the plasma levels up
 
red22 said:
Elaborate.

Also, Mistral and Grok are more lenient, Mistral being the more lenient of the two.
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I've worked through public AI and the techniques you can use to further increase how lenient they are e.g. let's role play. But it still hits limits.

so running a tweaked LLM with no safeguards is much more flexible, bit more info here

placebonaut

Computing Thread 'Help needed to test the accuracy of AI for recreational drug use'

I've been playing around with AI to do drug research and wanted to share my approach and get some help from the community to test how accurate AI currently is.

I am using KoboldCpp to run a Local LLM which has the safeguards removed from it, this seems to be 1 of the better models out there but it's a generation behind what you can access on the interweb (however that has safeguards in place so won't answer detail drug questions) - "Qwen3.6-35B-A3B-Uncensored-Genesis-APEX-Compact"

What I need help with are ideas for prompts which should return specific info about drugs which people...
  • Like
 
placebonaut said:
I'm giving this a go right now with 1500mg of Soma and can report success, onset for Meprobamate seems just as fast if not faster than sublingual, result!

Another cup of coffee on the go, some weed, and an omelette - breakfast of champs, at least the champs who like to chill the fuck out

I'm likely to redose another 500mg after 2-4 hours to keep the plasma levels up
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I'm glad to hear you experimented with this manually, out of curiosity do you suspect the pH of the water matters?
 
Esperighanto said:
I'm glad to hear you experimented with this manually, out of curiosity do you suspect the pH of the water matters?
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My "gut" feel on this is that it should alter how pills are broken down because my perception is they're usually chalky, though that's mainly a binder/filler thing, pills are designed to breakdown, just guessing that the choice of binder/filler is based on pH of the stomach to begin with.

IIRC someone mentioned somewhere taking pills with sparkling water to help accelerate onset, that's more acidic than still water so I could understand it helping, whether it's material enough or not is a different question, I suspect it might help a bit, but not as much as crushing them up, you want to get them into solution as quickly as possible because it increases surface area and therefore absorption rate. But with lots of oral drugs we're generally talking about half-lives that are much longer than the time it takes for a pill to breakdown, so not sure it's usually material enough to care about IMHO. For Soma trying to get it to hit as fast as possible seems to help me with intensity and consistency of effect, the minimum I do is break the pills up before swallowing them on an empty stomach, that's pretty good and no faff.

pubmed.ncbi.nlm.nih.gov

Food, gastrointestinal pH, and models of oral drug absorption - PubMed

This article reviews the major physiological and physicochemical principles of the effect of food and gastrointestinal (GI) pH on the absorption and bioavailability of oral drugs, and the various absorption models that are used to describe/predict oral drug absorption. The rate and extent of...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

But in terms of absorption it seems that Soma isn't effected by pH

"The solubility of carisoprodol is practically independent of pH"




1-s2.0-S0939641116305756-fx1_lrg.jpg
 
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