N&PD Moderators: Skorpio Forums Media, Science and Research Neuroscience and Pharmacology Discussion What determines how euphoric an opioid is? JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding. You are using an out of date browser. It may not display this or other websites correctly.You should upgrade or use an alternative browser. Members who reacted to message #10 All (2) Like (2) Nov 24, 2025 TheLightBringer Bluelighter Messages 676 Reaction score 649 Points 45 Aug 19, 2023 Abitofeverything Greenlighter Messages 26 Reaction score 4 Points 30 Loading… Forums Media, Science and Research Neuroscience and Pharmacology Discussion What determines how euphoric an opioid is?