N&PD Moderators: Skorpio Forums Media, Science and Research Neuroscience and Pharmacology Discussion Can anyone explain thru what mechanisms can amphetamines lower opioid tolerance JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding. You are using an out of date browser. It may not display this or other websites correctly.You should upgrade or use an alternative browser. Members who reacted to message #16 All (3) Like (3) May 19, 2025 ĐmantuNJofra Bluelighter · From Croatia Messages 652 Reaction score 345 Points 80 Aug 11, 2022 Neuroborean Bluelight Crew Messages 1,588 Reaction score 1,529 Points 95 G Jan 28, 2022 G_Chem Bluelight Crew Messages 7,872 Reaction score 10,422 Points 245 Loading… Forums Media, Science and Research Neuroscience and Pharmacology Discussion Can anyone explain thru what mechanisms can amphetamines lower opioid tolerance