N&PD Moderators: Skorpio Forums Media, Science and Research Neuroscience and Pharmacology Discussion Can anyone explain thru what mechanisms can amphetamines lower opioid tolerance JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding. You are using an out of date browser. It may not display this or other websites correctly.You should upgrade or use an alternative browser. Members who reacted to message #9 All (3) Like (3) May 19, 2025 ĐmantuNJofra Bluelighter · From Croatia Messages 650 Reaction score 345 Points 80 Jan 7, 2022 arrall Bluelight Crew · From Outer Space Messages 6,726 Reaction score 10,385 Points 320 Nov 20, 2021 plumbus-nine Bluelighter · From CDMX Messages 3,653 Reaction score 2,618 Points 70 Loading… Forums Media, Science and Research Neuroscience and Pharmacology Discussion Can anyone explain thru what mechanisms can amphetamines lower opioid tolerance