N&PD Moderators: Skorpio Forums Media, Science and Research Neuroscience and Pharmacology Discussion What do the sigma opioid receptors do when agonized? JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding. You are using an out of date browser. It may not display this or other websites correctly.You should upgrade or use an alternative browser. Members who reacted to message #3 All (1) Like (1) Sep 2, 2025 Smyth2 Bluelighter Messages 712 Reaction score 325 Points 180 Loading… Forums Media, Science and Research Neuroscience and Pharmacology Discussion What do the sigma opioid receptors do when agonized?