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Opana ER (In 24 hrs) overcomes Suboxone

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IHateOpiophobes

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I know that suboxone has one the largest affinities for the receptors in the brain, but I had 12 Opana 40mg, and after waiting approx 24 hrs (8mg a day Rx) I snorted 20 mg of opana and I was nodding out. I never did heroin, but I understand from that time what nodding out is. Anyone had similar experiences with opana and suboxone, or just opana. I traded them straight up 1:1 for a suboxone. I did them for a week, and 24 mg of suboxone was only just barely enough to keep withdrawal away. (minor sweats, little aches.) Powerful stuff. It breaks down into such a soft powder, and I think it "smells" great.

Info or experiences on Opana affinity. Not alot of research out yet.
 
Oxymorphone (Opana) is an extremely potent opioid. Trouble is, it only has a nasal BA of approximately 10%; so, at best, you are getting the net effect of 4mg for each 40mg pill you snort. Oh, and because it is Extended Release, it further makes absorption difficult and could result in less being metabolized.

The Opana ERs have a special ER delivery system called TIMERx that has been notoriously difficult to effectively break down or defeat. In my experience, they gel immediately upon contact with water and clog up my nose after a just a pill or two. It is a fun, yet generally short-lived high if you've got experience with medium- to high-strength opioids (and it sounds like you do, if you have Suboxone).

But, as far as having to modify your dose of Suboxone to deal with the ramifications of using Opana, I generally feel that this is largely unnecessary as long as you don't use for any periods longer than, say, 60-72 hours (without re-dosing on Suboxone). This will help to keep a constant level of buprenorphine in your system allowing you to easily get back on Suboxone after use.

I think the question you really need to consider is whether you truly want to be sober or not. I did a lot of jumping back and forth with Suboxone over the course of years and I do not recommend it. Aside from the shit being insanely expensive, you're just ruining your buzz if you're going to stay on Suboxone and continue to use recreationally.
 
IN BA is ~45%, IIRC. Oral BA is 10%. and the TimerX system is easily defeated by putting the Opana ER into a teaball, dunking the teaball into like 150mL of something 100proof, and letting it sit on a warm computer tower overnight. swirl it around a bit in the morning, pull out the teaball, evap the vodka and you have pretty much pure oxymorphone. You lose like 10%, tops.
 
This was the first time off sub in three years since starting.

fevio said:
Oxymorphone (Opana) is an extremely potent opioid. Trouble is, it only has a nasal BA of approximately 10%; so, at best, you are getting the net effect of 4mg for each 40mg pill you snort. Oh, and because it is Extended Release, it further makes absorption difficult and could result in less being metabolized.

The Opana ERs have a special ER delivery system called TIMERx that has been notoriously difficult to effectively break down or defeat. In my experience, they gel immediately upon contact with water and clog up my nose after a just a pill or two. It is a fun, yet generally short-lived high if you've got experience with medium- to high-strength opioids (and it sounds like you do, if you have Suboxone).

But, as far as having to modify your dose of Suboxone to deal with the ramifications of using Opana, I generally feel that this is largely unnecessary as long as you don't use for any periods longer than, say, 60-72 hours (without re-dosing on Suboxone). This will help to keep a constant level of buprenorphine in your system allowing you to easily get back on Suboxone after use.

I think the question you really need to consider is whether you truly want to be sober or not. I did a lot of jumping back and forth with Suboxone over the course of years and I do not recommend it. Aside from the shit being insanely expensive, you're just ruining your buzz if you're going to stay on Suboxone and continue to use recreationally.
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Yes there was no way only 10%. It was the first time actually getting high because everything else did not over-ride the bupe. I hope opana's stay a semi-secret. Because I feel bad for all the people really suffering because their OC's were cut off because of OPIOPHOBIA. All the robberies etc...Opana was mind bogglingly powerful. I would wake up each morning in withdrawal because it was so potent after 3 days. Good med for people who need it and use correctly.
 
IHateOpiophobes said:
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Yes there was no way only 10%. It was the first time actually getting high because everything else did not over-ride the bupe. I hope opana's stay a semi-secret. Because I feel bad for all the people really suffering because their OC's were cut off because of OPIOPHOBIA. All the robberies etc...Opana was mind bogglingly powerful. I would wake up each morning in withdrawal because it was so potent after 3 days. Good med for people who need it and use correctly.
Click to expand...

Also....before Opana O-morphone was only available in the hospital as numorphan. Very rare. So please people find another drug to become the media target. :)
 
yup, this stuff is potent, i'm a tolerant OC user. The Nasal BA is good enough that i don't feel like i'm wasting it when i snort it. I do usually 40 mg OC, 10 mg of Oxymorph was suffiecient to give me a nod the fuck out wake up on your keyboard drooling moment. Be careful with this stuff!
 
Opana is pretty much heroin in pill form. It is the pill that replaced the Oxy 80's. This is my choice in painkillers for a lot of reasons. They are very strong and you only need a little bit at a time to really get blasted. I do about 40mg a day, some days a little more. I know these can be dangerous and have seen people OD on just 1 pill. It depends on your tolerance and your body. I can do a good amount and be perfectly fine, a girl I knew did half of one and ended up in the hospital.

Discussion on the pills are they are very difficult to snort, which in my knowledge is totally wrong. The new ER time release does easily wipe off, all you need is a wet napkin. Or if your a chick long nails. It does grind up pretty well but can clog your nostril up very easy. I believe it was the Purdue company that makes these and I have heard that they had posted wrong information on the pill. But for the rumors of not being able to snort it are false!


**Also** I am an Opana addict, but on the medical side of everything. And for people who actually need them, they are very effective. They treat moderate to severe pain. You cannot get them as easily as lets say Percocet. They are given to people who are in severe pain. And not for post surgery uses. It is a long term use pill unlike a lot of the pain killers on the market. Again, please be careful with these guys, and really any pill in general. If anyone needs help or advice with these little guys feel free to give me a holler.
 
Opana is not heroin in pill form. Heroin is diacetylmorphine, opana is oxymorphone. There is no point in saying they are the same thing. Oxymorphone is much more potent.

And you shouldn't wet, or try to wipe off the coating, at all. You aren't wiping it off, just the color and then you are breaking it up and snorting it. You SHOULD scrape off the coating(like a chick with long nails), a fine edged razor blade or exacto knife works great.

But to the OP, was this your first time doing oxymorphone?

Buprenorphine definitely has a higher binding affinity and will block oxymorphone, I know this from personal experience.

After waiting 24 hours, and because of your personal chemistry, you had enough open receptors for the oxyM to be effective. That is all. The oxymorphone did not override the bupe, I promise. But, in my experience, because oxyM is so powerful it is able to "break through" bupe easier than say morphine or oxycodone. My hypothesis for this is because oxyM is such a powerful agonist it doesn't have to fill as many receptors to exert its effect, so when bupe only leaves a certain number of open receptors the oxyM works best. And bupe can be additive or supra-additive when you have enough open receptors.
 
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Coolwhip said:
Opana is not heroin in pill form. Heroin is diacetylmorphine, opana is oxymorphone. There is no point in saying they are the same thing. Oxymorphone is much more potent.

And you shouldn't wet, or try to wipe off the coating, at all. You aren't wiping it off, just the color and then you are breaking it up and snorting it. You SHOULD scrape off the coating(like a chick with long nails), a fine edged razor blade or exacto knife works great.

But to the OP, was this your first time doing oxymorphone?

Buprenorphine definitely has a higher binding affinity and will block oxymorphone, I know this from personal experience.

After waiting 24 hours, and because of your personal chemistry, you had enough open receptors for the oxyM to be effective. That is all. The oxymorphone did not override the bupe, I promise. But, in my experience, because oxyM is so powerful it is able to "break through" bupe easier than say morphine or oxycodone. My hypothesis for this is because oxyM is such a powerful agonist it doesn't have to fill as many receptors to exert its effect, so when bupe only leaves a certain number of open receptors the oxyM works best. And bupe can be additive or supra-additive when you have enough open receptors.
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If you read correctly, it is "pretty much" heroin in pill form. It is one of the strongest form of opiate that you will find in the form of a pill. And if you know anything about Opana or time release you would know that if you are snorting it, it will not be effective. You have to wipe the coating off before you can even grind the pill. Regardless if you scrap it off or wet it, either way you are removing the coating.
 
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lol

That colored coating has nothing to do with the time release.

You can grind up the pill without "wiping" the coating off, it will juts leave little specks of color in it. But anyways, I am telling you, and it would be good for you to listen, you can not wipe off an opana coating very easily(read: without fucking up the pill), you are just wiping off the colored part and then you are snorting the real "coating"(it isn't really a coating, just where you got the timerx wet). Once you get the pill wet the timerx bonds up to it, it won't come off very easily. You need to scrape it off while it is dry.

Opanas aren't like OG oxycontin, you have to remove the coating with something sharp. Moisture is the enemy until it hits your nose.

edit: changed oxycodone to oxycontin

edit: Just go take two opanas, lick the coating off one, and cut the coating off the other, break them up side by side. The one you got wet is going to be chunky(from where the timerx got wet and is holding the powder to it), and the one that stayed dry is going to be powerdery and light. and the one that stayed dry won't clog your nose up nearly as quickly, especially is you snort small lines in a row, instead of one big one.

ps: using your logic nearly every opioid is "pretty much" heroine in pill form. There is no point in saying that. It is untrue and dangerous, oxymorphone is much more potent.
 
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Coolwhip said:
lol

That colored coating has nothing to do with the time release.

You can grind up the pill without "wiping" the coating off, it will juts leave little specks of color in it. But anyways, I am telling you, and it would be good for you to listen, you can not wipe off an opana coating very easily(read: without fucking up the pill), you are just wiping off the colored part and then you are snorting the real "coating"(it isn't really a coating, just where you got the timerx wet). Once you get the pill wet the timerx bonds up to it, it won't come off very easily. You need to scrape it off while it is dry.

Opanas aren't like OG oxycontin, you have to remove the coating with something sharp. Moisture is the enemy until it hits your nose.

edit: changed oxycodone to oxycontin

edit: Just go take two opanas, lick the coating off one, and cut the coating off the other, break them up side by side. The one you got wet is going to be chunky(from where the timerx got wet and is holding the powder to it), and the one that stayed dry is going to be powerdery and light. and the one that stayed dry won't clog your nose up nearly as quickly, especially is you snort small lines in a row, instead of one big one.

ps: using your logic nearly every opioid is "pretty much" heroine in pill form. There is no point in saying that. It is untrue and dangerous, oxymorphone is much more potent.
Click to expand...

I understand where you are coming from, but I have been wiping off the coating every since they have been on the market. And never seen any clumping up and "water damage". You use a semi-wet napkin, and the my buddy who is a pharmacist id say that the coating on the top is the time released. And as for snorting it by this method, nothing ever got stuck in my nose or went wasteful. The powder is in a finely powder that you can snort without any problems. Maybe you've seen people do it wrong before, but I haven't.


edit: I have one OP with me I will PM you how the powder looks when I do the "wet" method.
 
This thread is still around......and here?

A funny note of entire irrelevance:

A call from a patient, "The pharmacist will not fill my prescription because he said the dose is too high [drug, gabapentin written as 300mg qid] ". A call is made to the pharmacist by physician, to the effect of, "Where the fuck did you go to medical school?".

Not that funny I suppose. My point is, your pharmacist friend sounds like a real piece of shit. However misguided, at least the pharmacist I alluded to appeared to be concerned about the said patients safety. The pharmacist you mentioned appears to be condoning or even promoting a means of abusing a narcotic formulation. Perhaps it is me, but there appears to be a significant difference between the European/Commonwealth equivalent (aka "Chemists") and the new generation American pharmacist (aka "rite-aid retard").

And with that, this thread should now be......a total loss........
 
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