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buying codeine in aus?

i have never had the itches after doing a CWE....300-400mg
however, i do with straight codeine phosphate pills....at 240mg.
no idea why! interesting though.
 
i have never had the itches after doing a CWE....300-400mg
however, i do with straight codeine phosphate pills....at 240mg.
no idea why! interesting though.

maybe that means the 300-400mg you think you're getting from CWE is actually less than 240mg. I get the itches late in night, and big time next morning if I were to consume in the evening. That's even with 15-20 tablets.
 
From all reports it seems like I'm surprisingly lucky when it comes to Histamine reactions. My Codeine experiences extend to ~450mg and I generally don't use, or need to use Anti-Histamines. I've had 1 or 2 medium histamine annoyances but I found the sedation of my most used anti-histamine (Promethazine) to not be worth the trouble.
 
I never experienced any sedation on (1st generation) anti-histamines. Which I find strange considering I know people who work in hospitals who have given them specifically for the sedating affect.
 
last night i bought a packet of panadeiene extras and for some fuckin stupid stoned reason, i kept thinkin it would be a 240 mg dose.. and after 30 minutes of havin it (i had a six pack of beer before hand) i relised it was a 360mg dose, 120mg more than the highest ive ever had and ive never really been itchy in my life up untill that point.... nearly tore all my skin out!! I was busted but lol

whata de fuck can i take to get rid of the itch? anything OTC??
 
You guys are lucky not getting a strong histamine reaction

On high doses of codeine it'll feel like my skin is sometimes burning...and I want to scratch my face off. A bit frightening actually.
 
Sameria I generally use doxylamine (brand name restavit) for the itch, I favour it to promethazine/phenergan because promethazine is a CYP2D6 inhibitor so I never dose that before the codeine, only after, where I can dose restavit first.

This is less of a concern for me now as these days I only itch mildly and if I do it is towards the end of the codeine high and lingers into the next day (much like bobbydarren reported) but I used to get a massive histamine released when it kicked in so doxylamine was much more useful.

These days if I use an antihistamine it is really just to add a little extra kick/sedation and not really to stop itching, for this reason I continue to use doxylamine as I find it a tad more sedating than promethazine. I always found promethazine seemed to extend the high somewhat, given that it is a 2D6 inhibitor this is likely due to it causing the codeine to be metabolised into morphine at a slower rate, another possibility is it also has an impact on the enzyme responsible for removing/metabolising morphine in the body.

I used brompheniramine a couple of times and found it to be less sedating than doxy or prometh, perhaps it would be worth a try. There are also non sedating antihistamines which you could look into, although I personally have no idea how well they go with codeine.
 
imo the whole euphoria of codiene is best observed lying in bed half asleep with the stereo on full ball and the bass turned up.

being awake and alert just leads to RAGE!!!:X
 
hmm from some of the posts in this thread it seems quite a few of you get enough 'effects' to nod on codeine?

i don't get anything even close off 200-250mg, more of a tweaked alertness combined with a bit of itching from the histamine effect, no euphoria or anything like that.

i think the highest i've done is around 350mg but didn't notice any benefit over the 200-250mg dose - is this just due to tolerance which i managed to build up even through minimal use (ie once a month or two)?
should i suck it up and try a higher dose to see if it gets any better?
 
^you probly reached your limit..
maybe try 400-500mg if you're feeling adventurous tho


I just always use opiates late at night before i go too sleep.. i think the natural circadian rhythms boost the euphoria and with codiene possibly even the metabolism into morphine.
codienes all bout dreams for me so all the stimulation is directed towards putting a massive shit eating grin on me face.
 
thats pretty gay lol, never really got much from it even to start with.

for those that are taking epic doses (ie. above 600mg) did you have to jump from a lower dose to try and find a dose that works for you, or was it a gradual thing that occurred due to tolerance over time?
 
Personally I feel about 500-600mg extracted from OTC tablets with reasonably good techique is about the maximum best effects you get from codeine, I feel for me personally whatever dose is left after you account for losses is around my ceiling dose so to speak (probably works out around the general consensus of 400mg or so). There are more metabolites of codeine than just morphine and codeine itself is somewhat active, I have dosed up to a gram or so and while the effects are increased, I find it less enjoyable because there is an increase in the amount of what I find to be more stimulating opiates but the morphine dose doesn't increase beyong the ceiling. I also find that whilst higher doses get you higher, per mg you get alot less return, for example 800mg is nowhere near double the high of 400mg.

Unless you are tolerant you will likely get very sick and a strong histamine release from high doses, especially without antihistamines, it is also a much more stimulating high in my experience and personally I like to take opiates to relax and ideally nod (although this is rare with codeine these days even with the addition of numerous potentiatiors).

Lately after some decent tolerance breaks I have found myself being able to get good effects for several days in a row without exceeding the ceiling, in the past I had an attitude where increasing the dose would make the high better and between that and use of harder opiates ended up with a tolerance where codeine did basically fuck all on its own but make me itch. I really think that while you can get stronger effects beyond ceiling doses unless you are an extensive metaboliser or want a speedier high and can handle the side effects it is pointless, and dosing this high also makes codeine a much less viable drug to get decent effects from with any regularity.

People seem to report more stimulating effects from lower doses but I never got this, codeine never did much beyond mild relaxation untill I started dosing above 300mg and unless I exceeded the ceiling it has always been a sedating buzz to me, although if I choose to I can function like I am pretty much straight I consider it a waste of the high, I really have to relax and embrace it to get good effects. Peoples reactions to drugs vary, one reason that seems somewhat likely to me is perhaps people who metabolise less codeine into morphine get the stimulating effects.

You really need a few tries to appreciate codeine fully I think, misk if I were you I would try a higher dose but parhaps keep an antihistamine on hand. I have to say I think codeine is one of the most under rated drugs ever, I have done most commonly available opiates but codeine just hits the right spot for me tolerance permitting.

Sorry I ended up rambling a bit, had a few bourbons and a nice CWE and got carried away lol
 
nice post lol.
i think i just dont get the sedating effects, don't have a problem with the histamine - my mrs has broken out in hives before, but other than a bit of itchiness i just get some nausea. i also have a long standing tolerance to anti-histamines, so have never had much relief when attempting to deal with the itchiness and just accept it as part of the experience.

i def get some stimulating effects and often do crosswords with the gf when taking codeine (sounds cheesy lol) and wont be able to sleep unless i have a xanax - so i feel increasing the dose would increase these effects more so than anything euphoric/sedative.

for me, the only thing that attracts me to it is mixing it with 6-8 travacalm HO and a few beers which gives me a bit of an awake K hole/stilnox dissociative style trip lol, but gets a bit hectic.
 
In my experience, I think I must get only mild itching.
I've only ever used CWE with 500/30 (Paracetamol/Codeine) tablets, to equal 300 - 400 Codeine (I'm slightly paranoid with the lower dosed Codeine tablets) and the itching I end up with, like a couple of others have said, is actually quite pleasant, so I don't mind it at all.

I'm thankful I don't get the itches like some of you though - that doesn't sound very enjoyable in the least.
 
Codeine is definitely my most favorite opiate!

d_m, I was under the impression that codeine was a strict prodrug and hence isn't active at all (until it's metabolised).
 
I have read a couple of places it was mildly active itself but it is definately mainly active as a pro drug. Perhaps where I read it is incorrect and codeine is totally inactive on its own, even still there are thought to be other metabolites of codeine responsible for its effects, codeine 6 glucuronide in particular I believe.
 
^ That is correct, in fact d_m mentioned that in his post a bit earlier on this page about promethazine inhibiting CYP2D6.

The antihistamine I'm using right now is dexchlorpheniramine (Polaramine). It's the least sedating of the first generation antihistamines, which I want right now because I've been using benzodiazepines with the codeine.

drug_mentor: I agree, codeine is highly under-rated... especially for those of us who can extensively metabolize and take our doses a lot higher then others. :D

ETA: You got in before me lol.

Codeine itself, before it gets metabolized, is definitely active in one way: releasing histamine. That's why it has a larger histamine release then many other opioids and can't be IV'd due to the risk of pulmonary edema.

The mechanism of action of the edema is kind of interesting itself; the huge histamine reaction leads to bronchoconstriction to such an extent that pulmonary blood pressure increases greatly and fluid starts moving out of the cells into the lungs. This doesn't happen often in common major allergic reactions, instead the bronchoconstriction just leads to difficulty in breathing and hypoxia.

Another interesting fact is that allergies to morphine and other opioids are highly over diagnosed due to their normal histamine release.
 
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