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MDAI + AMP= MDAish ?

concept

Bluelighter
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Jul 11, 2005
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West Coast, US
Given MDAI is an analogue of MDA without the catecholamine effects, and that MDA is to amphetamine, as MDMA is to methamphetamine. I was wondering how well MDAI would combine with amphetamines in creating an experience homologous to MDA? Anyone with experience using this combo? Anybody have experience with MDA, as well as MDAI with some type of stimulant who could conjecture?
 
Close, but not quite. MMAI has no affinity for serotonin receptors, MDA does and I'm sure that contributes to some of the psychedelic aspects.

It would nonetheless be an interesting combination to try. Take care with your dosing though :)
 
I've tried MDAI+d-amph & it was much more akin to MDMA than MDA. Like stated above, MDAI doesn't have any affinity for 5-HT2a as MDA does. MDAI a quite specific serotonin releasing agent, amphetamine is mostly a DA & NE releasing agent, combine those in the proper ratio & you've got, more or less, the profile of MDMA.

Do be careful with dosage when combining drugs though
 
AMD, were there any upsides to that combo compared to MDMA, lack of some side-effects? I have those compounds and would like to know for a later time. Also what was your dose proportion?
 
Well, the upsides were that you could toy with the ratios to come up with a more personalized "roll" so to speak. I tried a number of different stims in combo with MDAI, d-amph, buphedrone & M1. The former two were noticeably different from MDMA in the ratios i tried them. Usually 120-300mg MDAI with 10-25mg d-amph or 20-40mg buphedrone. Certainly MDMAish, but not quite as "messy," felt a bit more in control, also not as much gurning or unwanted peripheral stimulation as i get with MDMA. 200mg M1 & ~175mg MDAI was really indistinguishable from about 200-250mg MDMA.

All these doses are oral & approximate. I'll check my notes to be sure of their accuracy, but i'm pretty sure they're about right.
 
I've done aMT/MDAI/Adderall and, though I've never done MDA, that's the profile of monominergic release and 5HT2a agonism I was shooting for. It did feel like a trippier, more dopaminergic MDMA, but the serotonergic effects were probably a little overstated compared to what I imagine MDA would be. Whatever, though, it was pretty incredible and lasted far longer than MDA is said to (aMT really lengthens other triple releasers' peak effects as well).

The problem with aMT/other triple releaser combos is you can't know how aMT will enhance the effects of other compounds, and you're flirting with serotonin syndrome combining it with serotonin releasers. For instance, I took aMT and 4-FA and the synergism was really intense. It was only 12 mg IM (for the aMT -- about 25 - 30 mg oral equivalent) and 80 mg rectal for the 4-FA, but the result was probably the strongest chemical empathy I've ever felt, way above the sum of its parts. At the same time, though, combining aMT with MDAI (before I added Adderall) resulted in barely different effects than with aMT alone. It was until adding the Adderall that I noticed, "hey, this is different than my aMT/Adderall without MDAI experiences". Sorry, I forget the MDAI dose, but it was on the lowish end because of the serotonin syndrome concerns. Also, combining aMT with propylhexadrine resulted in an experience that did seem to be the sum of its parts, i.e. no synergy. So it's all unpredictable.

I can say that aMT smooths out the comedown of 4-FA, MDMA and propylhexedrine to the point where I don't notice it. I wouldn't take my experience as gospel, though, because I don't tend to get bad comedowns, not in terms of feeling sad at least (maybe a little with propylhexedrine, which is like meth to me). As expected, I felt significantly more emotionally flat during the following days than if I had taken just 4-FA or just MDMA, though.

As an aside, I've also been on a break from serotonin releasers for about 4 months now, as I was getting brain zaps after every time I did them by the end of my experiments. I'll be trying to stick to a once every three months at most schedule from now on.
 
As others have said, the MDAI and amphetamine combo is much more like MDMA than MDA. To make the combo feel like MDMA, make the ratio of MDAI:amphetamine somewhere between 7:1 and 10:1. It's not exactly the same, but it's damn close and a lot cheaper. The problem with this combo is that it's just as neurotoxic as MDMA. MDMA isn't that bad for you if used responsibly, but many people use this combo more often than they should. If you want a similar combo that isn't as hard on your brain, combine MDAI with a dopamine reuptake inhibitor rather than with a dopamine releaser. According to some studies, MDAI plus a dopamine reuptake inhibitor doesn't cause nearly as much damage as MDAI and a dopamine releaser. For the dopamine reuptake inhibitor, Methylphenidate works well in my opinion. If you also smoke a little weed or have a couple drinks, it makes for a very good high, probably like 85% as good as MDMA without most of the negative side effects.
 
According to some studies, MDAI plus a dopamine reuptake inhibitor doesn't cause nearly as much damage as MDAI and a dopamine releaser.

I find "studies" of these things, claiming all sorts of "damage" highly questionable... show me hard evidence of damaged neurons in a human that has used normal doses of MDMA or whatever. Yes that would probably mean someone that used them recently then was killed in an accident and was autopsied, including detailed electron micrographs of neuron structures.

Such studies do not exist so far as I am aware.

Everything else is just projected theory, test tube studies with petrie dish grown nerve tissue (probably from some animal) that is swirled in a test tube with immense concentration of an amphetamine soup.... VERY unlike the actual process as it occurs in a living organism.

Then there are the rat type studies that directly inject them with MASSIVE ODs of these drugs, then kill them and examine their brains. Again, VERY DIFFERENT than typical use by humans of comparatively small doses NOT directly injected.

That and the fact that the money usually comes from the DEA an so the researchers are highly motivated to create, er um find, results that are what the DEA want to hear.

So all these claims just involve HUGE levels of supposition and projection and are not true actual direct proof in living humans with known controlled exposure to precise doses and not a pile of other club drugs and party pills etc. that are adding who know what to the mix.

So... if you have links to the "Some studies..." you mention above I would very much like to see links to them exactly.
 
When I timed it right, I found MDAI + Adderall to be a dead ringer for MDMA, but with an ameliorated (yet not 'perfect') day after.

ebola
 
I find "studies" of these things, claiming all sorts of "damage" highly questionable... show me hard evidence of damaged neurons in a human that has used normal doses of MDMA or whatever. Yes that would probably mean someone that used them recently then was killed in an accident and was autopsied, including detailed electron micrographs of neuron structures.

Such studies do not exist so far as I am aware.

Everything else is just projected theory, test tube studies with petrie dish grown nerve tissue (probably from some animal) that is swirled in a test tube with immense concentration of an amphetamine soup.... VERY unlike the actual process as it occurs in a living organism.

Then there are the rat type studies that directly inject them with MASSIVE ODs of these drugs, then kill them and examine their brains. Again, VERY DIFFERENT than typical use by humans of comparatively small doses NOT directly injected.

That and the fact that the money usually comes from the DEA an so the researchers are highly motivated to create, er um find, results that are what the DEA want to hear.

So all these claims just involve HUGE levels of supposition and projection and are not true actual direct proof in living humans with known controlled exposure to precise doses and not a pile of other club drugs and party pills etc. that are adding who know what to the mix.

So... if you have links to the "Some studies..." you mention above I would very much like to see links to them exactly.

Take a read. The intro basically explains it. Could you find holes in it? I have no doubt you will. But if so, then find something better. http://www.erowid.org/references/refs_view.php?A=ShowDoc1&ID=691
 
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