"Rebuilding" the brain

[mgmt&mdma]

try 5htp

taking 5htp for extended period of time has been shown to DOWNregulate 5HT (serotonin) receptors.

i GaGa btw

 

[mgmt&mdma]

See I don't want to avoid my current depression , I want to solve it for the long run, mainly my mental capabilities so I can get back to school, I have a feeling staying away from AD's is the way I should go and naturally let the brain do it's thing.

do you take any multivitamins?

IME the best thing to do to treat depression without help from the doc is to invest in a multivitamin and to start working out.

 

[pofacedhoe]

dont take tramadol it does blunt cognition and its also habit forming as hell after awhile. stick with all natural.

it never blunted my cognition noticably and i was working the whole time i was on it. i didn't find it addictive, more simply i just took it once in the morning every day.

since being on it i find myself less easily upset and i dont feel rejected anywhere near as often as i used to before it. for some reason its left me with thicker skin personality wise, although not initally when i came off it

also strong b vitamin complex is amazing for depression

 

[somedud]

do you take any multivitamins?

IME the best thing to do to treat depression without help from the doc is to invest in a multivitamin and to start working out.

Oh yeah every day, plus I run and body build daily. I'm 5 days into my cessation of lexapro, and am going to cycle SJW, along with some of my Nootropics, such as curcumin, Ginko, Aniracetam, Pyritinol, PhosphatdylSerine, bacopa, CalMag, b complex, inositol and niacin.

I'm concerned though, I'm taking an amino acid complex with tons of 5htp, in it, SJW is an SDN-RI and curcumin and Ginko are MAO-A/B inhibitors. SSRIs caution towards this combo, but I'm wondering if it would be safe with 5htp and SJW?

 

[mgmt&mdma]

^^i commented ur thread in ED about the 5htp and sjw.

and if ur workin out and taking all those supplements i think you should be set haha, good luck!

Does gingko help rebuild the brain btw? why r u taking it?

 

[arohydro]

Prove it.

SSRI's have shown to induce neurogenesis in the hippocampus.. this is one theory as to how they work as it starts (or atleast gets to a significant phase) at around 3 weeks from begining treatment.

Took the words right out of my mouth. I don't understand the 'reverse stigma', if you will, regarding SSRIs among the drug using community. Sure, they're not for everyone, and are overprescribed, but to say they are useless I think is a bit tactless.

 

[somedud]

^^ agreed. I was against them all my life, until I abused MDMA and was bed wridden for months. Needless to say, within 4 weeks I was working, running, reading and body building after 6 months of hardcore depression.. Clearly wasn't a placebo, nor would I suggest long term use, 2 months was sufficient for me.

Tianeptine is my next step after SJW to upregulate my receptors from the downregulation caused by the SSRIs. I've hears some promising things about Tianeptine and receptor repair, anyone have any studies or abstracts to confirm this?

 

[M Brace]

I sympathize with your depression. Been in that place many times, before and after I first used MDMA. It can and will get better.

My belief is that you can't really point to a single cause for depression ( or anything else really ). Not to get too philosophical... There are many flavors of depression and many effective remedies.

I've done the high dose SJW thing a couple times. It was a mildly effective anti-depressant at 6000 + mg per day.

5-htp helps smooth out the mood drops in the days after using MDMA. But long term it didn't seem to help.

L-Tyrosine seemed to help for a couple weeks after using MDMA, which has me wondering if Dopamine systems shouldn't be given equal weight with serotonin systems when discussing rebuilding the brain following MDMA abuse.

Ketamine and DXM have some anti-depressant qualities worth exploring.

Piracetam rules, always.

But by far, the best anti-depressant I have used is SAM-e. Avail over the counter in US. I used 1600 mg per day. That's the highest recommended dose.
Started noticing results on the first day.

That's all just from my personal experience. IMO MDMA isn't likely the sole cause of your symptoms, but the psychedelic space that you entered gave you a heightened, or different awareness that allowed these symptoms to manifest.

Hope you feel better soon.

 

[rickolasnice]

If you are suffering some lingering depression for MDMA then you probably don't need to start using drugs to combat it.. it'll get better anyway.

To help speed things up have a healthy diet, get some regular exercise and lay off the drugs..

 

[rickolasnice]

the best anti depressant i ever took (and i took it after a few weeks of mdma binging) was tramadol, once daily in the morning.

far superior to ssri's. i never needed to up my dose either. coming off them was weird and a bit uncomfortable but knowhere near the empty cold horror of coming out of the citalopram bubble.

Tramadol use can very easily lead to tramadol abuse and addiction.. probably shouldnt be the first thing you use to combat depression.

Also.. i was on citalopram for 7 months at it's highest dose at 2 points in my life.. both time's i just stopped taking them and experienced pretty much no change.. definitely no withdrawals.

I think courses of SSRI's should not go on past 3 - 4 months.. maybe even less.. as i doubt it's having much benefit and probably just causing psychological (maybe physical aswell) dependence.

If the theory of neurogensis within the hippocampus being the reason SSRI's work is true.. then surely as soon as the patient feels better, they should stop.. as the new / fixed neurons are not just gonna decide to die again. This would be a 3 - 6 week course. Dependence would not have had time to develope and all the good the drug can do has been done.

I wonder if doctors have ever tried it? Put someone on a course for a month then taken them off once they feel an improvement? I bet if doctors told the patients that that's all they need and the improved mood / sense of well being should be somewhat permanent.. the patient will never get that "it was the drugs that made me happy, now i need them" way of thinking.

I was against them all my life, until I abused MDMA and was bed wridden for months. Needless to say, within 4 weeks I was working, running, reading and body building after 6 months of hardcore depression.. Clearly wasn't a placebo, nor would I suggest long term use, 2 months was sufficient for me.