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HOW LSD affects other receptors?
- Thread starter mrdocat
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This research summary suggests dopamine is not affected...
Can you elaborate on why you are asking this? Because I cannot really imagine that single time use of LSD (by you) would account for the symptoms you've been having explained by reduced levels of dopamine unless you are extremely sensitive with your dopamine balance. In any case it would suggest an underlying condition which is probably better not classified by a simplistic explanation of "lower levels of some neurotransmitter" but it is much more complex and best explained in a psychological or psychiatric frame. Do you understand what I'm trying to say?
Let's say for a minute that you would find an explanation that vaguely fits, one that cannot be disproven but is uncertain nonetheless. Would you try to increase your dopamine levels by trying to find nootropics or supplements that have been said to do this? MY concern is that people who are having persisting symptoms that impair their functioning try to self-remedy with smartdrugs based on beginner knowledge on matters and far too great expectations of the healing effects.
If you are asking this for a whole other reason then you have my apologies - I am not trying to come off patronizing at all, my disposition is to try and help.
If I am on the right track with what I am thinking (because I look at your previously created threads and remember them), can you hear me when I say that I've seen too many people who have troubles and instead of looking for help try to fuck with their neurotransmitters, which doesn't help at best or makes matters worse if you are unlucky.
Nootropics and similar compounds can have benefit for concentration, improvement of functioning of your brain in general and those sorts of things but it's madness to try and cure something with them when you don't even understand what's wrong.
Can you elaborate on why you are asking this? Because I cannot really imagine that single time use of LSD (by you) would account for the symptoms you've been having explained by reduced levels of dopamine unless you are extremely sensitive with your dopamine balance. In any case it would suggest an underlying condition which is probably better not classified by a simplistic explanation of "lower levels of some neurotransmitter" but it is much more complex and best explained in a psychological or psychiatric frame. Do you understand what I'm trying to say?
Let's say for a minute that you would find an explanation that vaguely fits, one that cannot be disproven but is uncertain nonetheless. Would you try to increase your dopamine levels by trying to find nootropics or supplements that have been said to do this? MY concern is that people who are having persisting symptoms that impair their functioning try to self-remedy with smartdrugs based on beginner knowledge on matters and far too great expectations of the healing effects.
If you are asking this for a whole other reason then you have my apologies - I am not trying to come off patronizing at all, my disposition is to try and help.
If I am on the right track with what I am thinking (because I look at your previously created threads and remember them), can you hear me when I say that I've seen too many people who have troubles and instead of looking for help try to fuck with their neurotransmitters, which doesn't help at best or makes matters worse if you are unlucky.
Nootropics and similar compounds can have benefit for concentration, improvement of functioning of your brain in general and those sorts of things but it's madness to try and cure something with them when you don't even understand what's wrong.
Dondante
Bluelighter
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Solipsis said:
Exactly.
Smaller bars indicate higher affinities. Receptors with bars below the line are affected by a typical dose of LSD. Dopamine is probably only affected at high doses. Regardless, LSD would not cause a dopamine imbalance.
But it binds strongly to 5HT2A which down regulates dopamine, not?
Solipsis,
5HTP + SSRI worsened it.
Solipsis,
http://www.ncbi.nlm.nih.gov/pubmed/3374263
5HTP + SSRI worsened it.
Dopamine Deficiency said:
Did you read my whole post?
Like I already said, as far as I heard you used it once. Even if you are getting symptoms you that coincide with dopamine deficiency, after one LSD trip I understand?... What is the point, I already asked IF this is the case what will be your next action?
It doesn't matter really. This should not be discussed here but with a professional. Not once have I heard you talk about that option, and you haven't really met my arguments at face value.
This is not about who is right or wrong, not at all. I am only worried you might be on the wrong path with this and wish you would try another. Since you are your own person and you have your own responsibility this is your choice, but as I have said before if you ask these questions I ask of you that you investigate the answers, the whole matter, completely.
Otherwise it would be like you were a ghost roaming besides the point.
Perhaps it is easier to continue on with "yes but..." ;
though if you want PD's platform to host your inquiries try to confront these difficult questions I ask. It's only fair.
Anyone else is welcome to voice their opinion on this - I hate dogmatism and appreciate democracy.
Like I already said, as far as I heard you used it once. Even if you are getting symptoms you that coincide with dopamine deficiency, after one LSD trip I understand?... What is the point, I already asked IF this is the case what will be your next action?
It doesn't matter really. This should not be discussed here but with a professional. Not once have I heard you talk about that option, and you haven't really met my arguments at face value.
This is not about who is right or wrong, not at all. I am only worried you might be on the wrong path with this and wish you would try another. Since you are your own person and you have your own responsibility this is your choice, but as I have said before if you ask these questions I ask of you that you investigate the answers, the whole matter, completely.
Otherwise it would be like you were a ghost roaming besides the point.
Perhaps it is easier to continue on with "yes but..." ;
though if you want PD's platform to host your inquiries try to confront these difficult questions I ask. It's only fair.
Anyone else is welcome to voice their opinion on this - I hate dogmatism and appreciate democracy.
rollingstoned!
Bluelighter
This question all depends on the dose of lysergic acid diethylamide. If you even got true LSD, and not LSP,LSB, DOx,....
You were right in the first post but you said it like I was completely wrong for going though that path. I have read it all. Well, what will I do... I think I'll find a way to augment my dopamine. I know and I understand your advises, but what else can I do? What would you do if you were me? The last doctor just prescribed me another SSRI. If SSRI's lowers dopamine they worse every single symptom I related and he knew that. So seriously fuck with those professionals. Maybe you got serious psychiatrists there. Here in Brazil things are not like that.
EDIT: I'm thinking in Selegiline, Adderal (not to treat, just to test and confirm if it's it). I don't know anything about how to augment dopamine.
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telepathetic
Bluelighter
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mrdocat: please stop posting so much about this. I told you, you've just become a hypochondria. look up generalized anxiety disorder. You've probably just got HPPD with really bad depersonalization/derealization.
Look at my older posts (click my name and click all threads started by yourtman) look at mine from 6 months to a year ago and I was just like you.
Look at my older posts (click my name and click all threads started by yourtman) look at mine from 6 months to a year ago and I was just like you.
telepathetic
Bluelighter
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telepathetic
Bluelighter
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and my only other advice is to stop trying to diagnose yourself - let the professionals do it - you know nothing.
......................this is a long, dark road man, so be careful. I spent a year there. I'm finally back. Just recently i stupidly started taking benzos for fun now im going to have to deal with the rebound which could send me back there- ill probbably beat it with good ol' diphenhydramine.
anyway, if you listen to me and just stop, it'll get better in a few weeks, if you dont it'll go something like this:
1. you'll keep trying to diagnose yourself, thinking you have a brain disorder
2. you'll continue this for a few months and feel like shit throughout
3. you'll start to think of physical things - mine was lymphoma since all my lymph nodes are palpable - and obsess about that.
4. You'll go thru anything and everything and think you have it.
5. Some kind person will tell you its just in your mind.
6. about a year later you'll realize he was right, and finally start fixing it.
maybe take another LSD trip
anyway thats how it went for me YMMV
telepathetic
Bluelighter
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this topic is about you man.
Go ahead and get on 100000000 medicines and be doped down or just wait it out and stop feeding the cycle.
His PM to me. Dawg, I am 100% better. And there is nothing wrong with you. Now stop fucking asking because your making it worse man.
his other PM to me. I'm not going to be talking to you in PM's, nor will I feel your cycle. You don't know what you are talking about at all. You're fine. That is all.
Go ahead and get on 100000000 medicines and be doped down or just wait it out and stop feeding the cycle.
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I don't think it's fair to ask people about the theory of LSD pharmacology if you don't really understand what you are messing with. If you think this board is to help people regardless of whether it is wise to do something, that's only true up to a certain point. The main goal is harm reduction and I interpret that to be whatever it is that does the least harm and the most good.
If I believed that a single trip could make your dopamine levels plummet like that, and that it would be wise to experiment with things like adderal (amphetamine as a sustainable anti-depressant or something similar, I think not - it would be a miracle if you wouldn't feel WORSE after it wears down!!!) I would help support your theories in that direction.
From what I know SSRI's also enhance the dopamine system, so my advice is to at least try the medication that is prescribed to you - though I hear you about the unprofessional doctors. If it doesn't do you any good which takes time to find out because you have to adjust to the stuff... then explain your theories to the doctor and convince him or her to help you look for more atypical medication, Wellbutrin or something? Hell I don't know.
Perhaps yourtman's attitude is not completely called for but I agree that you are showing signs of hypochondria and are looking in the wrong places in the wrong ways to find out what's wrong and being panicky about it. It just doesn't feel right to enable that plus I wouldn't like to see you hurt yourself even more with experiments. Because that's what you are suggesting: experimenting on yourself with, from what I can tell, a lack of understanding.
And a very realistic alternative to prescriptions or self-medication is therapy. You don't even sound like you are remotely considering the psychological aspect of what your symptoms tell, not everything is chemical/clinical! It sucks if you cannot get good therapy in Brazil - for some reason I thought you were in Portugal? - it also makes your questions for help very hard but that is not to say you can damage yourself more with improper self-medication as opposed to meager professional help.
Instead of asking about receptors and nothing more (as if you don't need a context to get worthwhile information) if I were you I'd at least ask what other people's ideas are about your theory in the first place. If PD is lacking a keen eye then I'd be fine with moving this thread to ADD. Perhaps those folks have more intelligent things to suggest than your doctor?
I don't want Bluelight or myself to be judgemental. And I am not putting in effort to consider your issues to judge you. Again: it just seems unethical to help you continue with your own personal plan, so I hope you see how I mean all of this constructively.
If I believed that a single trip could make your dopamine levels plummet like that, and that it would be wise to experiment with things like adderal (amphetamine as a sustainable anti-depressant or something similar, I think not - it would be a miracle if you wouldn't feel WORSE after it wears down!!!) I would help support your theories in that direction.
From what I know SSRI's also enhance the dopamine system, so my advice is to at least try the medication that is prescribed to you - though I hear you about the unprofessional doctors. If it doesn't do you any good which takes time to find out because you have to adjust to the stuff... then explain your theories to the doctor and convince him or her to help you look for more atypical medication, Wellbutrin or something? Hell I don't know.
Perhaps yourtman's attitude is not completely called for but I agree that you are showing signs of hypochondria and are looking in the wrong places in the wrong ways to find out what's wrong and being panicky about it. It just doesn't feel right to enable that plus I wouldn't like to see you hurt yourself even more with experiments. Because that's what you are suggesting: experimenting on yourself with, from what I can tell, a lack of understanding.
And a very realistic alternative to prescriptions or self-medication is therapy. You don't even sound like you are remotely considering the psychological aspect of what your symptoms tell, not everything is chemical/clinical! It sucks if you cannot get good therapy in Brazil - for some reason I thought you were in Portugal? - it also makes your questions for help very hard but that is not to say you can damage yourself more with improper self-medication as opposed to meager professional help.
Instead of asking about receptors and nothing more (as if you don't need a context to get worthwhile information) if I were you I'd at least ask what other people's ideas are about your theory in the first place. If PD is lacking a keen eye then I'd be fine with moving this thread to ADD. Perhaps those folks have more intelligent things to suggest than your doctor?
I don't want Bluelight or myself to be judgemental. And I am not putting in effort to consider your issues to judge you. Again: it just seems unethical to help you continue with your own personal plan, so I hope you see how I mean all of this constructively.
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IamMe90
Bluelighter
you're a little melodramatic prick who can't take advice from people who know more than you about this. why make the topic in the first place? you already know what you want to do, so continue down your misguided path and pump yourself full of dopaminergic drugs (that you seriously consider taking adderall as a solution to your depersonalization proves that you don't know what you're talking about imo)
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