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Stimulants Dexedrine (dextroamphetamine) Intranasal?

MMMMKAY?!

MMMMKAY?!

Ex-Bluelighter
Joined
Jul 28, 2010
Messages
489
I know the bioavailibity of dexedrine oral is 75%, How good is it intranasal? what percent bioavailibity. Just tell me what you think thanks! By the way Dexedrine (dextroamphetamine) is basically adderall. Adderall is 3 fourths Dextroamphetamine. And Dexedrine is pure DextroAMP. (Much better in my opinion).
And also I am not on the Capsules I am on the Pressed pills (easy to crush and snort)
 
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Where did you find the oral BA is 25%? I've only seen sources that say 75%

A quick search showed that racemic amphetamine's intransal BA is 75% so I wouldn't imagine just the dextro enantiomer is substantially different but I am not positive.
 
Insufflation BA is lower than the oral BA.

Its hard to say how much lower, as there are so many variables. However, it is significantly lower.
 
^Do you have any sources or are you going based on your own experience? If the latter, please make sure to note that next time and not state it as fact.

When it comes to something such as bioavailability, please only post something that you can back up with sources.
 
Cane2theLeft said:
Where did you find the oral BA is 25%? I've only seen sources that say 75%

A quick search showed that racemic amphetamine's intransal BA is 75% so I wouldn't imagine just the dextro enantiomer is substantially different but I am not positive.
Click to expand...

sorry bout that ment 75.
 
Cone said:
Insufflation BA is lower than the oral BA.

Its hard to say how much lower, as there are so many variables. However, it is significantly lower.
Click to expand...

Are you serious? because 20mg dexedrine Intranasal is like 40 mg oral for me
 
My seat of the pants estimate has always been about twice as strong intra nasal too, but with a duration of only about half as long as oral. Alkaline urine will keep it from clearing your system, and longer it hangs around the longer you'll enjoy it. Your gonna pee a bunch out unchanged any way you look at it.
 
oldkaw said:
My seat of the pants estimate has always been about twice as strong intra nasal too, but with a duration of only about half as long as oral. Alkaline urine will keep it from clearing your system, and longer it hangs around the longer you'll enjoy it. Your gonna pee a bunch out unchanged any way you look at it.
Click to expand...

Totally agree exept I dont get the peeing part lol
 
I'm in the UK, where we only ever get 5mg dex pills - and they're pretty big (i.e full of filler, no other actives) for 5mgs. When I first started getting them, I tried crushing them to snort - problem was, one pill would make 3-4 fat lines, and a HORRIBLE nasal drip would follow, plus my nose would run for half an hour. No improvement in BA - even 50% - was worth the drip/losing half the line in mucuous. I guess with higher dose pills, it might be worth it.
 
Well, like I said in another post, 30%+ is excreted in the urine unchanged. If you want to go green, or coal miner style, you can recycle, and sell it to your friends.
 
^^There have been many threads on this for some reason.

I don't have any sources, but my personal experience with snorting 5mg and 10mg dextroamphetamine instant release (Barr Labs brand, I don't know what you all are getting in the UK) and snorting crushed up dextroamphetamine extended release 10mg (also Barr Labs brand) is that the availabilities are close, snorting brings you up quicker but also brings you down quicker. The usual "YMMV" disclaimer applies because I don't have any sources.

On a side personal note, I usually snort and then eat an equal amount of Dexedrine if I'm doing that method, that way I get the best of both worlds.
 
^^It certainly can, and it also contributes to the drip :(

I don't know about others, but the Barr Labs brand have a lot of fillers for a 5 or 10mg dose, that's for sure.

I don't know what brand the OP is using...
 
NeighborhoodThreat said:
^^On a side personal note, I usually snort and then eat an equal amount of Dexedrine if I'm doing that method, that way I get the best of both worlds.
Click to expand...

Yeah i get the 30's scored into quarters. Snort a quarter to get it goin, and eat a quarter. Depends on you too. If i eat too much I get all gittery and anxious. Snorting seems to come down right when that begins, so that part ain't so bad.
Even after I come down a little after snorting a quarter I still feel focused, and somewhat energetic for while.
 
Everywhere I've real that an alkaline stomach will greatly increase the feeling of them. Recommendations have been to take the tabs with a 8oz glass of water mixed with about a table spoon or two of Baking Soda
 
I haven't snorted dex in years. Mostly it was a high school DOC since all my rich classmates had parents that found dex/prozac/boarding school easier than rules/parenting.

Anyways. The effects of eating dex, ritalin, adderal etc vs snorting are differentiated by onset speed and peak duration. I don't know the precise BA of either method but a general rule of thumb would be snort it for a baby rush or eat it for a nice lil plateau.

I agree with the posting suggesting to eat some and snort some.


A little side note. When I took my SATs (1998) the first time sober I got a 1280. Second time six months later I took 20 mgs dex and got a 1390. In between the two I discovered LSD. Academics....
 
Cone said:
Insufflation BA is lower than the oral BA.

Its hard to say how much lower, as there are so many variables. However, it is significantly lower.
Click to expand...

I find that extremely hard to believe : o
 
I would not be surprised if the nasal bioavailability was lower than oral bioavailability, but the nasal has a much greater peak concentration resulting in a greater high.
 
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