Whats better in your opinion 20mg opana ER or 8mg dilaudid IR

[HT harm redux]

Im going to see my pain doctor tomorrow and im gonna try to have him take me off opana and oxies in favor of just being on dilaudid. i know the best roa with dilaudid is IV and id have no problem finding a rig. so in this forums opinion should i stick with the opana and oxy for breakthru? or should i try to get back on the dilaudid?

 

[K'd-OUT-in-AZ]

IVing 8mg of dilaudid is going to be much more powerful than snorting opana.
8mg of hydromorphone is equivalent to 53.3mg of oxymorphone (oral) so probably 30-35mg insufflated since the BA of oxymorphone (insufflated) is "almost" twice as much as the oral route.

 

[Alcyone]

I can't really answer the OP's question, but based on personal experience I'd say that oxymorphone is a whole lot more than twice as potent when insufflated compared to the oral route (or rectal, for that matter).

Oral bioavailability of oxymorphone is about 10% according to wiki and other sources. I haven seen any figures on the nasal BA, but I'd say it's in the range of 80-90%. I've only had the Opana IRs and not the ERs, but I found that 2-3 mg snorted equals about 20 mg plugged/swallowed, or about 40 mg oxycodone. Not sure how it compares to hydromorphone, though.

 

[K'd-OUT-in-AZ]

I can't really answer the OP's question, but based on personal experience I'd say that oxymorphone is a whole lot more than twice as potent when insufflated compared to the oral route (or rectal, for that matter).

Oral bioavailability of oxymorphone is about 10% according to wiki and other sources. I haven seen any figures on the nasal BA, but I'd say it's in the range of 80-90%. I've only had the Opana IRs and not the ERs, but I found that 2-3 mg snorted equals about 20 mg plugged/swallowed, or about 40 mg oxycodone. Not sure how it compares to hydromorphone, though.

No way is it 80-90%! No insufflated route of any drug would yield such a percentage. It is not that high. From what I've heard it is roughly 50%. From my experience 5mg equals about 20mg oral

 

[HT harm redux]

Im going to do my best to get the hydromorphine because i know that the opana ER has that timerX mechanism in it and im sure that stuff up your nose is not a very good thing. Ive been on dilaudid before then my doc switched me to mscontin and roxys and kept raising my mxcontin dose to the point i was on 200mg of a day of mscontin and 60 mg of roxys. i think its a good argument for the case of dilaudid cuz id rather just be on 8 mg of dilaudid every four to 6 hours again rather than taking so many other things. and it would be cheaper on my insureance.

 

[K'd-OUT-in-AZ]

You can defeat the time mechanism by taking the coating off with a razor blade, crushing, making small lines and slowly snorting it.

Only if you plan to IV would the Dilaudid be a better option. If you plan on snorting or taking orally then GO WITH THE Opana. Its much stronger than those routes. 8mg of Dilaudid will do nothing orally or insufflated, you won't feel it at all if you used to take 200mg MSContin & 60mg oxycodone.

 

[HT harm redux]

thank you all for the input but if i do end up getting hydromorphone i will definitely be getting rigs

 

[NeighborhoodThreat]

Dilaudid

 

[Alcyone]

No way is it 80-90%! No insufflated route of any drug would yield such a percentage. It is not that high. From what I've heard it is roughly 50%. From my experience 5mg equals about 20mg oral

Sir, I stand corrected. It's in the range of 50% like you said. Although certain nasal drug preparations do have bioavailabilities approaching 100% (glucocorticoids like fluticasone, for instance).

But if 5 mg insufflated equals 20 mg oral to you, then why did you say its BA is almost twice as high in your initial post?