Why is methamphetamine psychosis stronger than amphetamine's?

[ektamine]

It seems to me that methamphetamine has a much greater ability to cause serious paranoia and amphetamine psychosis much stronger and quicker than amphetamine. I draw this from both personal experience and anecdotal evidence. It feels to me like amphetamine, without horrendously pushing the limit, nearing OD territory even, will fail to produce the anywhere close to same intensity and quick onset of paranoia/psychosis as methamphetamine. Methamphet seems almost inseparable from the horrible paranoia when used recreationally. I notice a lot of talk about how in European recreational drug culture, this is a major reason for amphetamine being so much more prevalent then its methyl brother.

Can anyone shed some light on this?

I apologize if this has been asked before, I UTFSE'd on 3 search engines (both bluelight searches and a general google search) but found it a rather hard topic to utilize a search engine for because of the massive amounts of topics & information on the general subject of amphetamine psychosis, not specific to the differences between substances.

 

[ResearchChemMrE]

meth gives you the rush and the dopamine, ser., nor. ader. that it releases in that short amount of time prob. has a huge effect on why it is more addicting.

 

[BIGsherm7272]

Well meth is much stronger than straight amphetamine, releasing dopamine at a much quicker and stronger rate, which can cause extreme paranoia/psychosis......that is why most anti-psychotics mainly antagonize your dopamine receptors

 

[sekio]

Meth releases serotonin in addition to dopamine/norepinephrine, which amp releases

 

[ektamine]

Meth releases serotonin in addition to dopamine/norepinephrine, which amp releases

Yeah I'm aware of the serotonin component of meth, but if that was a major contributor to the p/p I would think that MDMA, being another major serotonin releaser would also cause extreme p/p. But it doesn't, at least in my experience.

Well meth is much stronger than straight amphetamine, releasing dopamine at a much quicker and stronger rate, which can cause extreme paranoia/psychosis......that is why most anti-psychotics mainly antagonize your dopamine receptors

Thanks for your answer. So the rate seems to play a role as well then, your suggesting? This makes sense, as like I noted in the OP.. I feel like I can take so much amphetamine that I feel way higher than the minimal amount of methamphetamine I would need to induce psychosis, without getting psychosis. So I would think that my dopamine levels would also be getting pretty high on the straight amphet, but the consequences, not so much.

 

[K'd-OUT-in-AZ]

I think that it has something to do with how its produced because anyone who takes pharmaceutical methamphetamine, like me, will tell you that there is little difference between Desoxyn and Dexedrine. I've abused both and will tell you that you'd get the same degree of psychosis from either.

 

[Gormur]

Hmm.. amphetamine psychosis is definitely more severe than methamphetamine psychosis for me

For one thing, I can't stay up for days on meth like i can on d-amp. It mellows me out, and when i come down, it's so gradual i fall asleep once it wears off

D-amp makes me somewhat even-tempered, but in large doses i'd be zooming around aimlessly and feeling fucked up days later

 

[K'd-OUT-in-AZ]

For one thing, I can't stay up for days on meth like i can on d-amp. It mellows me out, and when i come down, it's so gradual i fall asleep once it wears off

You can't stay up on methamphetamine like you can on d-amp? Damn. I can't stay up longer than a couple nights on d-amphetamine but on methamphetamine I've gone about a week without sleep and complete and utter psychosis.

 

[Gormur]

I think that it has something to do with how its produced because anyone who takes pharmaceutical methamphetamine, like me, will tell you that there is little difference between Desoxyn and Dexedrine. I've abused both and will tell you that you'd get the same degree of psychosis from either.

This is more-or-less the distinction my mind makes:

low-dose d-amp: i'm clear-headed, better able to focus
low-dose d-meth: i'm relaxed and focused

high-dose d-amp: i'm awake but fucked up.. my thoughts are racing, on-edge
high-dose d-meth: i'm relaxed and focused. my thoughts become abstract and creative

basically d-amp makes me feel like i'm high on a drug while meth keeps me relatively coherent by comparison

 

[Gormur]

You can't stay up on methamphetamine like you can on d-amp? Damn. I can't stay up longer than a couple nights on d-amphetamine but on methamphetamine I've gone about a week without sleep and complete and utter psychosis.

I've also stayed up for a week on meth, but i was smoking almost nonstop the entire time, going through 4 or 5 grams

Oral and nasal doses have kept me up longer, but i've never been up longer than 1 1/2 days (less than 48hrs) from one dose like i have with d-amp

 

[K'd-OUT-in-AZ]

D-Amp keeps me going for maybe 4-6 hours. The extended release maybe 8 hours, although sometimes I'll fall asleep after a few hours. I'd have to be redosing many times on doses up to 150mg to be able to stay up for a day. If I take about 350mg of Adderall I can stay up for a couple days. Its hard though because I'll usually crash by the second night.

Doing a bump or a hit of meth will get me going for a solid 8-12 hours. A gram will keep me going all day. I'd also need about 5 grams (at least) to stay awake for a week.

 

[LivingOnValium]

lol

You can reach the same level of psychosis with amphetamine as you can with meth and it's not even that difficult. You just need to take larger doses to compensate.

 

[phatass]

well methamphetamine is more powerfull for the good effects as well as the side effects compared to plain amphetamine

 

[34-dihydroxyphen]

Glad there is no meth in my area, cause I certainly would have fucked with it a lot back in the day (I might have tried it once, sold to me as coke in the hood, it was way stronger than d-amphetamine and actually felt euphoric).

However, I have had quite a few d-amphetamine binges. I usually do not experience full blown psychosis til I am up for 5 days, with minimal psychotic effects emerging on day 4. If I go past day 4, I am in for some deep shit. So I don't.

I definitely don't want to fuck with meth if it will bring on psychosis quicker. Amphetamine psychosis was one of the worst experiences in my life.

Although it wasn't as bad as a Brief Psychotic Episode I once went through without using any drugs. Staying up for days, hallucinating, not knowing where the fuck I am, talking in my sleep about things that I can never repeat to anyone because of how fucked up they were, and in my moments of sanity (where I had the partial realization that something was seriously wrong, even though I kept spitting out delusions), generally being worried about whether this was going to be permanent or not. Amphetamine psychosis doesn't even compare.

 

[ektamine]

lol

You can reach the same level of psychosis with amphetamine as you can with meth and it's not even that difficult. You just need to take larger doses to compensate.

I'm sure you can, but as I said in my original post, I have taken high, prolonged doses of both, and I would compare (from my experiences) the psychosis caused by d-amphetamine from being ultimately spun, to the psychosis caused from d-methamphetamine from being at a place where I could and would definitely want to be higher still. It just feels disproportionately different to me, compared to the actual high, and positive effects caused by each. thats all.

 

[K'd-OUT-in-AZ]

lol

You can reach the same level of psychosis with amphetamine as you can with meth and it's not even that difficult. You just need to take larger doses to compensate.

Not to dick size but I've taken up to 400mg of Adderall and amost 300mg of Dexedrine, redosing after redosing and could not stay up past 2 days. I just eventually pass out. I could have taken more but I just zonked out before I could. It just would not be possible.

Methamphetamine I can go through an eight ball and be up for 5 days. If I had more I could continue to go longer. I don't just pass out eventually but just keep going.

Amphetamine psychosis to me is basically becoming horribly paranoid and start to hear voices. During a psychotic break from methamphetamine I start seeing people who aren't there. I don't get that bad with amphetamine.

 

[ektamine]

Not to dick size but I've taken up to 400mg of Adderall and amost 300mg of Dexedrine, redosing after redosing and could not stay up past 2 days. I just eventually pass out. I could have taken more but I just zonked out before I could. It just would not be possible.

Methamphetamine I can go through an eight ball and be up for 5 days. If I had more I could continue to go longer. I don't just pass out eventually but just keep going.

Amphetamine psychosis to me is basically becoming horribly paranoid and start to hear voices. During a psychotic break from methamphetamine I start seeing people who aren't there. I don't get that bad with amphetamine.

Couldn't have said it much better myself. Except I might add that m-amp has me fully psychotic when I reach that point, stuffing shit in my key holes and putting tin foil by the windows so I can hear them before they get in, that type of thing. Plain old amp has me hanging in at a comfortable, mostly paranoid with a chance of psychosis. Should clear by tomorrow for sunny skies :D

Though I do try an avoid both, these days

 

[K'd-OUT-in-AZ]

Couldn't have said it much better myself. Except I might add that m-amp has me fully psychotic when I reach that point, stuffing shit in my key holes and putting tin foil by the windows so I can hear them before they get in, that type of thing. Plain old amp has me hanging in at a comfortable, mostly paranoid with a chance of psychosis. Should clear by tomorrow for sunny skies :D

Though I do try an avoid both, these days

Oh God the key hole thing. I will sit looking through it for hours. I will sit on a chair staring at the door. I will then peak out of the curtains every 10 minutes. Of course the blinds are closed. I'm not exactly sure who I'm expecting to come but I've got a gun under the couch...waiting. I'll be inside talking to myself trying to hide from the shadow people. If somebody else is with me we'll work as a team looking through the key hole and window. If we actually see a real person we go insane and start wondering if they are real or fake. We go nuts!

 

[ektamine]

Oh God the key hole thing. I will sit looking through it for hours. I will sit on a chair staring at the door. I will then peak out of the curtains every 10 minutes. Of course the blinds are closed. I'm not exactly sure who I'm expecting to come but I've got a gun under the couch...waiting. I'll be inside talking to myself trying to hide from the shadow people. If somebody else is with me we'll work as a team looking through the key hole and window. If we actually see a real person we go insane and start wondering if they are real or fake. We go nuts!

Wow. K'd-OUT, you remind me ALL too much of myself. Your stories are creepy familiar. I invite you, to have a look under my couch cushion:

NSFW:

 

[K'd-OUT-in-AZ]

LOL, that's good to help keep the shadow people away. I got a Winchester Bowie for Christmas that I keep under my bed cushions. Its longer than 12 inches.