Heroin ok to preload syringes?? if i cant do it later??

[nycfc]

i live with my girlfriend and i was wondering if i could mix up a bag, load it into the syringe, and then cap the syringe and put it away to shoot about 10 hours from now. i know its not difficult to load a syringe but it would make it a lot more practical if i could just jump into the bathroom with something ready to go so that i take the least amount of time possible.

will it settle in the solution? what if i just shook it up or flicked it a few times?

 

[HdoubleODeezy]

when heroin is in water for an extended period of time it turns to morphine.

 

[muvolution]

i would keep it in the fridge at least. But that's not really a good idea.

 

[f13nd]

If you don't want it to revert to morphine perhaps u can carry little glad jars and some pre rolled up cottons so you can load on the go (its what I used to do )

 

[Cane2theLeft]

when heroin is in water for an extended period of time it turns to morphine.

You're right but not in 10 hours time. Eventually it will hydrolyze into morphine though.

This has been brought up A LOT so there is a lot of great information on this around the forum. Start with the "search" tab at the very top of the page next to the "new post" tab, go to 'advanced search' and play around with the search options and you should be able to find a lot of discussion on this topic.

Its always a good idea to search before starting a new thread because 90% of the time, the topic you're interested it has been covered ad nauseum.

If you have questions or anything, feel free to private message me.


________________________

Keep in mind first and foremost that even with filtration, there will be a substantial amount of bacteria left in your shot that will rapidly multiple when left in water. Its essentially a cess pool and you're certainly and unnecessarily increasing the dangers and risks by leaving a solution in a syringe (or other water) unless you're using bacteriostatic water and micron filtering.

Check out Captain.Heroin's micron filtering mega thread in the Directory for more information on this.

 

[phr]

Besides hydrolyzing into morphine, you have to consider the risk of bacterial growth.

So yeah, decreased potency and increased health risk. Not worth it, especially when it can be sniffed.

 

[tablehead]

Oooh this kinda scared me, I always considered it a nono to preload, cause half the time after loading a syringe, and missing the vein over and over (not injecting and missing but trying to draw back and missing) I find that after a 10 min human pin cussion session when I look in the syringe some of the mixed in heroin seperates from the water and leaves little flakes/chunks in my syringe.... is this the case or am I just not using my cottons correctly sometimes...?

 

[w0ntbackd0wn]

Even if it does turn in to morphine you'll still get high. I use to do it all the time and I still always got high.I'd pull the plunger to the back and shake it up a little bc it would look like something settled towards the bottom but after shaking it up a little it would be good to go.

 

[TwoOnSmack]

You're right but not in 10 hours time. Eventually it will hydrolyze into morphine though.

Could I ask you for a reference on this timeframe mate? Not that I don't believe you, but I'd find it cool to see some info on the stability of opiates in solution.

I wouldn't worry about bacterial growth though. Provided that we're dealing with a sealed volume of solution, you will have the same bacteria present as when you sealed it (hopefully none!). However, if you're sloppy/non-sterile and some bacteria make it into the solution before sealing off the syringe, these can of course multiply while the solution is being stored.

 

[Cane2theLeft]

^there's no way you're going to eliminate 100% of the bacteria, EVEN with micron filtering and with illicit drugs, there are never perfect conditions.

Regarding the rate of hydrolysis-
(emphasis added)

Spontaneous hydrolysis of heroin in buffered solution.

Smith PT, Hirst M, Gowdey CW.
Abstract

Electron-capture gas-liquid chromatography was used to study the spontaneous hydrolysis of heroin in phosphate buffer (pH 6.4 and pH 7.4) at 23 degrees C. Aliquots of solution were taken over a 24-h period. After extraction at pH 8.9 into propan-2-ol (10%)-ethyl acetate, deacetylated products were made into hepafluorobutyrate derivatives which were analyzed quantitatively using nalorphine as the internal standard. Heroin decomposes to 06-monoacetylmorphine (06-MAM) under these conditions. Further decomposition to morphine was not observed. Spontaneous hydrolysis was faster at pH 7.4 (first-order rate constant, 9.6 x 10-5 min-1) than at pH 6.4 (first-order rate constant, 3.0 x 10-5 min-1). In 24 h, the decomposition to 06-MAM was 13 and 4%, respectively.

PMID: 688091 [PubMed - indexed for MEDLINE]

EDIT:

Here is a good BL thread on the subject and where I first saw the above abstract first referenced.

 

[tablehead]

Even if it does turn in to morphine you'll still get high. I use to do it all the time and I still always got high.I'd pull the plunger to the back and shake it up a little bc it would look like something settled towards the bottom but after shaking it up a little it would be good to go.

What's the risk in injecting these settlement particles? Blood clots? Ect..

 

[Cane2theLeft]

^that sounds awful. Whatever those particles are, they are not heroin or morphine that are readily water soluble. You need to be filtering better.

 

[tablehead]

^that sounds awful. Whatever those particles are, they are not heroin or morphine that are readily water soluble. You need to be filtering better.

I was thinking it was because I didn't filter right with my cotton but as the other poster I would only see this percipitates after the solution was left 15 minutes or longer in the syringe...

 

[TwoOnSmack]

^there's no way you're going to eliminate 100% of the bacteria, EVEN with micron filtering and with illicit drugs, there are never perfect conditions.

Regarding the rate of hydrolysis-
(emphasis added)



EDIT:

Here is a good BL thread on the subject and where I first saw the above abstract first referenced.

Thank you good Sir! I've downloadet the paper and will print it for my good-night reading.

With regards to micron filtering and bacteria, I can only speak from personal experience. I use the same filters in the lab for sterilizing various solutions before adding them to culture media plates. When doing this I always perform a control experiment with the same solution on indicator plates - plates designed to support the growth of a wide variety of bacterial and fungal species. None of these have indicated any biological contamination ascribeable to the filter-sterilisation process.

However, these are my own personal experiences (i.e. anecdotal evidence)and I haven't really read anything on the subject of filter sterilisation as such. Are you saying that the micron-filter will let some bacteria through the filter itself or are you saying that even when micron-filtering, some bacteria will inevitably find their way into the solution after filtering? With a mesh of 0,2u I think the filter will retain all bacterial species familiar to me.

Maybe I'll try cooking up a filtered shot and then inocculating a series of plates with the shot itself....

 

[dokomo]

With regards to micron filtering and bacteria, I can only speak from personal experience. I use the same filters in the lab for sterilizing various solutions before adding them to culture media plates. When doing this I always perform a control experiment with the same solution on indicator plates - plates designed to support the growth of a wide variety of bacterial and fungal species. None of these have indicated any biological contamination ascribeable to the filter-sterilisation process.

However, these are my own personal experiences (i.e. anecdotal evidence)and I haven't really read anything on the subject of filter sterilisation as such. Are you saying that the micron-filter will let some bacteria through the filter itself or are you saying that even when micron-filtering, some bacteria will inevitably find their way into the solution after filtering? With a mesh of 0,2u I think the filter will retain all bacterial species familiar to me.

The 0.2u pore size is only an average, there are larger and smaller pores in the filter. Also, many people do not adequately pre-filter when it's necessary, which can cause failure of the micron filter. Contamination post-filtration is always potentially a problem if the person is not using proper sterile technique.

 

[Cane2theLeft]

^thanks dokomo... as usual, you said it better than I'm able.

TOS- you clearly know what you're talking about (and know more about this subject than I do) but this isn't the case for most people who are using intravenous drugs so you have to expect a far larger margin of error such as dokomo elucidated.