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Long term effects of E use - be aware...and how to rebuild brain?

Beyondme

Greenlighter
Joined
Dec 13, 2010
Messages
2
Hi everyone,

New to this forum and I've been reading a lot.

As brief as possible, I took my first ecstacy at 17, in a safe supported quiet space. I took it a couple of times 17-18 after. I didn't take it during my gap year at 19 but age 20, for a good year, I took alot. I was having social challenges starting Uni and self medicated...I also absolutely loved psychadelic trance. I had some wonderful times. Mind blowing, literally. To hazard a guess, which is very hard but important to do, I took it every week to every other week/3weeks for a year, maybe year and half. I had it one more time at age 27...with lots of drink and 30 hour party binge. Sometimes I'd take 2-3 pills on a big night. I also dabbled in other things, trying everything under the sun. I went too hard.

I developed clinical depression in my second year and ended up having to defer my last year. I finished in the end - I worked extremely hard to make up. But not without antidepressants and a disasterous past of police record, abortion, affair with married man, an STD from my ecstacy induced mess. Awfull things. Lots of it was due to pre existing self esteem, but without a doubt was made what it was because of my irresponsible drug use.

The reason I'm writing. Here I am, just turned 28. No established career, nothing to show for myself. That again can't be blamed linearly on the drug, but the deep depression took on a snowball effect that has led me to here. I fall in and out of depression now. Additionally, I think the level of ecstacy use destroyed so many fundamental footings in my brain, my personality. I have little creativity, lack the ablity to know how I feel or what I want. The worst - I have cognitive issues that I worry seriously that are a result of the party time; I have little working memory, my memory recall is poor, I struggle to find words, string scentences, problem solve, make connections, take information in, remember things, pay attention. I have problems of delayed gratification, I'm over emotional.

I have been exploring pre existing Attention Deficit Disorder. Understanding this condition and attending a workshop on it, this could be a cause of all these issues. The impacts of this condition and damage from ecstacy use are simlar - damage to the prefrontal lobe.

I really regret going so hard with the partying. I'm angry I didn't reach out more rather than self medicate. I believe you can avoid the damage taking it easy and doing it occasionally, supporting your body in the process. PLEASE TAKE HEED - I beg all users to take it easy. I know most people here do. But Look out for others who seem to be irresponsibly self medicating - going it too much. If they don't have the family support, no one will care. Its friends responsibilty to look out for each other. It is not worth the pain for the rest of their life.

Anyway, the real reason I posted - Can people please recommend what I can take to rebuild brain power? What things are proven?

Thank you!
 
What other drugs were you or are you still using? weed?

The best way to get better is to stop using all drugs other than those prescribed by your doctor.

Lots of good exercise which in turn will help you to sleep better which is also important and a good healthy diet.

Keeping the brain active is also great and if you are not in a position where this occurs naturally then try doing puzzles such as sobico or whatever its called.

Its also very possible that you really dont have any serious physical issuies but that you are suffering anxiety which makes you believe that you have the issues.........mind you just as real as if they were physical.................but requires retraining the brain.

I would also suggest you see a doctor who may be able to arrange some tests to find out if there is any physical damage. This will help to determine the correct approach.
 
excersize, sleep, muilti vitamin, fish oil, and maybe look into piracetam or aniracetam + choline bitartrate (the best bang for your buck choline). Aniracetam has some anti anxiety elements to it for some people. Ive read that Acetyl L Carnitine (ALCAR) can help rebuild brain cells.

From a theraputic stand point you should go see a doctor and maybe arrange for some cognitive behavioural therapy (CBT) which works at changing your attitudes and beliefs to relieve anxiety and depression, with remarkable success
 
How long ago did you stop doing ecstasy? A powerful story, and my heart goes out to you, but I can't help but wonder how much of these issues are caused by the ecstasy abuse, and how much by other factors. I'm not saying that abusing ecstasy doesn't do damage, but I do think people in your situation seem to blame a lot of their issues solely on ecstasy, when it could be a combination of things.

Anyway, since it seems by your story that you recently stopped abusing, many of the negative effects from the abuse should fade with time. I myself have experienced ecstasy abuse, and while I was recovering, everything seemed so monumental, my issues were blown way out of proportion in my own mind. All I could think at the time was that I had fucked my brain beyond repair and I would never feel normal again. I asked myself over and over again why I had done such a thing. As time passed though, these effects faded, things started becoming more clear, and I feel great now, because I take care of myself. I realize now how much of the negativity was inside my head, and how many of my problems were also related to other things going on in my life, and simply magnified by the continuous lack of serotonin in my brain.

Anyway, I wish you nothing but the best. You'll have to let us know how things go for you.
 
I know a lot of people who have been through your situation who now have problems in the same sense that you do. Memory problems, speech problems, lack of focus, poor motivation...

All of these things not a previous issue until they abused MDMA.

So I agree. It's a good drug and can do wonderful things if used correctly and in moderation.

Edit: Mind you, I have ADHD and GAD, and though both were pre-existing conditions diagnosed by doctors before I started using drugs, I always sort of feel like the few weeks after I drop E always agitate my condition and make it worse.
 
Thank you for sharing your story and I hope that things improve for you.

I am always saying take it easy, go slow, give yourself a break between rolls as these stories are all too common on the scene.

Normally people get in to deep and the endless parties, drugs (not just E), being awake for days on end just simply gets too much for them. Especially when they are tying to / or should be studying.

I think the best things are what MazDan said, quit the drugs and look after yourself and see how things improve.
 
Hi everyone,

I truely appreciate your responses.

I havn't touched E since I was 23 - 5 years. I knew it was doing me damage and completely stopped. I was drunk one eve at 27 years old, and some idiot gave me ecstacy. Being drunk I didn't have the sense to not take it...30 hours later I came out of alcohol ecstacy stupor throwing up bile. Never ever had I mixed the two in my early days. I only dabble in a few mushrooms now, very occasionally but will not anymore. I drink gently but find I'm very foggy days after. So anyway - I don't play with things anymore and I think I'm even going to stop drinking for a while, even the nice evening glass of wine.

Actually I have been quite healthy since my crazy days, in an attempt to heal myself - I exercise fairly often, I often eat organic and high nutrient, done many cleanses, played with native American medices, even did a 6 week cycle of yoga, cleansing, primal therpy and silent retreat meditation in a rainforest! My mind is still imblanced. It feels physical.

yet I appreciate that yes, people in my situation have complex histories and i certainly had mood issues before I took, you never know how that has impacted the now. And I'm always trying to asses whether my inherent lack of self belief, tendency to be negative about myself and abilities and anxiety around these things...and naturally the depressed state this can cause, is a cause of the cognitive things. After a while if they are so embedded I think they can be a cause.

It's so hard to pin cause and effect. and so hard to know how to approach where I am now. A big part of me says its medical, something is wrong, and another part doubts and thinks its my thought processes that i cant seem to manage effectively. Do I pursue the unhelpful doc for ADD screen (in uk v hard to get diagnosis), pursue the CBT Ive been put forward for, take lots of supplements, accept I'm not as clever as I thought (maybe its that!), pay thousnads to have brain scans (wont be public here). I've spent thousands already trying to find more balance and contentment. Supplementing etc.

Still, ecstacy played a significant part no doubt.

I'm going to explore some supplements and let you know how I get on! Thanks x
 
Honestly, i'm worried hearing this story. I'm going through the same thing, my cognitive abilites are VERY VERY dull compared to what they use to be, no more complex thinking, executive functioning, priortizing, etc.. Im only 4 months in so i'm hoping these recover. As for a suggestion to you, as i'm probably going to fly to somewhere to do this, neurofeedback/biofeedback , aprreaerntly very good in retraining your brain, especially around possible damaged areas that you believe to be present.

PhosphatylSerine has alot of positive replies, Ginkgo Bilbola increases blood flow to the brain, Lions Mane enhances NGF (effects after 6 months) 500 mg morning 500 mg night, Bacopa has an anti anxiety affect and appearently some neurogenerative effects after 3 months... 1 g in morning.. Just a suggestion.
 
When I hear the stories of other people, I start to think that Ecstasy must be very selective in how it affects people. If anybody should have lasting damage from Ecstasy, I would think it would be me. I used for 10 years with perhaps the last 5 years in an abusive pattern. The frequency wasn't so abusive, no more than monthly, but when I did use E I would take repeated doses over 8 to 12 hours with a total dose 500mg to 800mg common.

Anyway, the point is that during much of that time I did feel dumbed down and had trouble finding words, expressing ideas, processing complex or complicated concepts, solving puzzles, etc. I also experienced heightened anxiety and toward the end dealt with depression that would last longer and longer each time - up to 2 to 3 months toward the end - ultimately the major factor that scared me away from using regularly.

My point to all this is that all it took was 3 months of not using, and I was pretty much back to my old regular self. Prior to using I was a straight A student in university, a math whiz, had a sharp memory, was really good with words and spelling, and was a quick thinker. Now at age 36 I feel just as sharp as ever and in some ways even more perceptive and quick to learn now that I have life experience. I don't say any of that to brag, but just to illustrate that abusing Ecstasy does not necessarily mean you're brain damaged and will never be normal again.

I don't doubt that abusing E can contribute to some negative effects, and it's definitely a high priority to quit if you're experiencing mental problems; but at the same time I also think that Ecstasy is probably just one of a wide variety of factors that figures into mental health.
 
When I hear the stories of other people, I start to think that Ecstasy must be very selective in how it affects people. If anybody should have lasting damage from Ecstasy, I would think it would be me. I used for 10 years with perhaps the last 5 years in an abusive pattern. The frequency wasn't so abusive, no more than monthly, but when I did use E I would take repeated doses over 8 to 12 hours with a total dose 500mg to 800mg common.

Anyway, the point is that during much of that time I did feel dumbed down and had trouble finding words, expressing ideas, processing complex or complicated concepts, solving puzzles, etc. I also experienced heightened anxiety and toward the end dealt with depression that would last longer and longer each time - up to 2 to 3 months toward the end - ultimately the major factor that scared me away from using regularly.

My point to all this is that all it took was 3 months of not using, and I was pretty much back to my old regular self. Prior to using I was a straight A student in university, a math whiz, had a sharp memory, was really good with words and spelling, and was a quick thinker. Now at age 36 I feel just as sharp as ever and in some ways even more perceptive and quick to learn now that I have life experience. I don't say any of that to brag, but just to illustrate that abusing Ecstasy does not necessarily mean you're brain damaged and will never be normal again.

I don't doubt that abusing E can contribute to some negative effects, and it's definitely a high priority to quit if you're experiencing mental problems; but at the same time I also think that Ecstasy is probably just one of a wide variety of factors that figures into mental health.


People with higher IQ'S have more cognitive reserve and can damage their brain alot more than someone with an average to low iq. They also have more capacity to repair as they likely carry the more highly expressing gene for brain derived neurotropic growth factor. So this may be why you didnt notice any damage.

I myself have an average IQ and it only took me taking MDA a few times to fuck myelf for YEARS. Some are just luckier than others.
 
People with higher IQ'S have more cognitive reserve and can damage their brain alot more than someone with an average to low iq. They also have more capacity to repair as they likely carry the more highly expressing gene for brain derived neurotropic growth factor. So this may be why you didnt notice any damage.

I myself have an average IQ and it only took me taking MDA a few times to fuck myelf for YEARS. Some are just luckier than others.

Uhh....link?
 
What things are proven, you say? Good question

Abstinence. First and foremost, from any oxidizers. Save it for special occasions, to maximize positive impact. When pioneers like Sasha say "once every 3 months", they don't mean to imply that your head will fill with holes the minute you take it at 2 months and 3 weeks. You could probably, with proper supplementation, get off safely on 125 mg every ten days, but then it becomes less special... and less special implies habit, which in turn implies dependency... see where this goes? You see alcoholics doing the same thing with something far more clumsy and toxic everyday. Long story short... its not the abstinence that counts, eventually, so much as what you bring to the experience: either a person with their own honest life, warts and all, or a dependent abuser whose brain is still trying to sort itself from the last time.

Sleep: most of the repair happens during a quality, uninterrupted 5-10 hours of sleep. I will say this more than once: your dreams will tell you when...

Fishoil. By the handful. Your brain is mostly fish fat and water... I'm sure one of the neuroscientists could give a more accurate answer. If you must, take a Linseed or hemp oil or something... but be reminded that fish caps are still the most efficient.

However, you might still be worried about your brain's future... Some kind of ion-channel cleaner, like Piracetam (although Aniracetam has a roughly-just-less-than-equivalent half-life, it stays in the system longer and some find the effects a little less manic [if one could completely apply such a term to one of the 'racetams]). Search for an amino-acid complex called 'neurotine' which is basically anything an even-erstwhile user would need. SAMe is another. Do some research... the racetams are truly wonderful time machines for the brain...

After all that, you may still be wondering 'when'? Like I said: never be afraid of REM sleep as a diagnostic tool. After the withdrawl-induced night terrors (no sh1t) I would dream about it for up to about two weeks after... kind of like those bathroom dreams where you never quite find one... kids wake up with wet sheets, adults wake up with memories of Homer Simpson's flushing meadows routine dancing in their heads. You basically crave the state of bliss, but its not there to be had, especially not in a dream state which is mostly due to what you experienced while up and about.


I don't know if any of my old posts are here, but I can say without a doubt that I too, have attempted to treat the psychedelic amphetamines like so much after-dinner beer, with extremely limited success. I wish I had had the knowledge, although it was out there. The process of rebuilding took some time, but eventually I was able even to surpass the state I was in before I went nutso on the psychedelic amphetamines.

The cognitive deficits are sometimes just as amusing and as alarming, but in my experience, the sense of distance from one's former self is probably the worst long term effect, even more so than the immediate depression, or even the dreams of a guy on my back chopping me with a machete.
 
You say that you tried yoga, but I would recommend beginning/maintaining an ongoing yoga practice.
I would also recommend learning/practicing meditation.
These are the two keys that have helped my mind/brain recover from what damage I did in my youth.
If you do an hour of yoga and/or meditation every morning, you will clear your mind and allow your brain to reset itself naturally.
I have learned that it is better to miss an hour of sleep and keep up my practice than to allow myself to sleep in and miss my chance.
Doing yoga/meditation makes me feel better all day - better, even, than sleeping that extra hour.

As others have mentioned, exercise and healthy food are also important.

Best of luck to you.
 
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