butterybagel
Greenlighter
- Joined
- Nov 15, 2007
- Messages
- 1
Can anyone comment about the oral activity and/or duration of action of JWH-200? Any info about rectal administration? Thanks! bb
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Jwh-200
butterybagel
Greenlighter
Can anyone comment about the oral activity and/or duration of action of JWH-200? Any info about rectal administration? Thanks! bb
Thanatos
Bluelighter
Any info or updates? I can't wait to try it!
fryingsquirrel
Bluelighter
Isn't this the one that will form a hcl salt? That at least should be fully active orally.
MurphyClox
Bluelighter
I would not say "fully active", but certainly with more reproducible results than e.g. JWH-018. Any why the hydrochloride? Citrate or tartrate should work, too, and are very benign.
No personal experience with bioassaying though.
Peace! - Murphy
fryingsquirrel
Bluelighter
Well, none other than having a gallon of hcl acid in the garage.
Any why the hydrochloride?
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I am toying with the thought of buying some. I enjoyed 018, but had a horrible panic attack from eyeballing it. Now, I moved to a state where its been outlawed. Which is kind of funny, because I am on the state line between another state where it is legal. Shops posted up right on the line with huge K-2 signs. Anyhow, excluding the digression.
If anyone has tried it and feels like letting me/us know the details, I would appreciate it.
fryingsquirrel
Bluelighter
I have, was not really impressed. I found jwh-250 much better. I live in one those states, too.
I am toying with the thought of buying some. I enjoyed 018, but had a horrible panic attack from eyeballing it. Now, I moved to a state where its been outlawed. Which is kind of funny, because I am on the state line between another state where it is legal. Shops posted up right on the line with huge K-2 signs. Anyhow, excluding the digression.
If anyone has tried it and feels like letting me/us know the details, I would appreciate it.
fryingsquirrel
Bluelighter
Other than the lower potency (perhaps 073 dosage), the main difference was the lack of 018 type panic, even with eyeballed doses. Other than myself all smoking it were jwh virgins and they had no problems.
What were the differences you found between 018 and 250?
Hammilton
Bluelighter
After trying a few of the AAI's a bit more, I'm off the mind that JWH-073 is my favorite. It's practically entirely in my head, none of the physical tinglyness of JWH-018. If its duration was extended by 60 minutes it'd be perfect. I find it hard to get really stoned on it, but that's not my goal. I want my back to stop hurting and to get to sleep. It helps with the back for sure, but whether it helps a whole lot with sleep, I can't say
FloridaHighs
Bluelighter
3x higher binding affinity to cannabis receptors, but less sedative effect (e.g., less high
)
http://www.scied.science.doe.gov/scied/JUR_v2/pdfs/Miller.pdf
melange
Bluelighter
I never really got the "panic" effect from 018 everyone is saying they have had
Hammilton
Bluelighter
I'm not meaning to suggest that everyone's experience will be uniform, as I never really did either, but it seems that "the terror" people describe is the result of an overdose. Once dosing higher than usual, but nothing extreme, I had about as much anxiety as I did when I first tried really good cannabis (the second time I had ever smoked at all, and two years after the first. Large bong, and made the rookie mistake of holding the smoke far longer than necessar. Unforgetable experience-- too bad I was freaking out so much- might have enjoyed it more).
If you never overdosed at all, that's probably why.
People don't realize that these are full agonists, and you can get dangerously intoxicated from them. There are numerous reports of people being taken by ambulances, rushed to ER's, seizures, fainting, racing hearts and high BP, when using JWH-018.
Agreed, Hammilton. Any time I smoked to much hash or dank to keep up with everyone else, I had a panic. So, I knew it had to be an overdose. I should have had listened to the people telling me eyeballing was stupid. Live and learn.
Now, concerning the potency difference between the two. I like the idea of less of a stoney high. I just want to ease off my anxiety. I can't be super stoned all the time. In the words of the great Katt Williams, "I got shit to do today".
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Other than the lower potency (perhaps 073 dosage), the main difference was the lack of 018 type panic, even with eyeballed doses. Other than myself all smoking it were jwh virgins and they had no problems.
i hear 081/250 in a 1:1 ratio is just like 018 can anyone confirm?
fryingsquirrel
Bluelighter
Maybe in subjective affects, but IIRC 081 is more like 250 or 073 level of potency. But in general mixing jwh's seems to be the way to go, I find they feel more like the real thing that way. Haven't tried that combo, or 081 by itself for that matter. Probably next on my list, though.
i hear 081/250 in a 1:1 ratio is just like 018 can anyone confirm?
kaossalami
Bluelighter
The oral dose of JWH-200 should have a greater oral bioavailabilty than jwh-018. JWH-018 has a pretty short half life, when smoked, so i would guess that the half life of jwh-200 is a bit longer orally.
Hammilton
Bluelighter
JWH-018 almost certainly has a very long half life, actually. That's part of where the concerns about carcinogenic potential are stemming from.
They're so lipophillic they're probably going to be similar to THC (maybe not as long, perhaps longer)
fryingsquirrel
Bluelighter
Yes, half life and duration of effects are two different (although not totally unrelated) things.
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