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  • MDMA Moderators: Esperighanto

Does xtc cause holes in the brain?

are you retarded?
how would you be able to LIVE with HOLES in your brain?
edit:
meth doesnt put holes in your brain either
and i will bet you money, meth is easier on your brain than E.
dopamine systems recover faster than serotonin, bud.
E isnt good for your brain, at all, thats why youre not supposed to roll often
i guarantee you one use of methamphetamine is easier on your brain than one use of MDMA.
and that doesnt take into account when people get speedy/meth pills which will increase the neurotoxicity.
meth might be nasty, but its not completely horrible and e might be "socially acceptable" but its FAR from good for you.
and meth is FAR from the only droog that can cause brain damage. i guarantee you MDMA can cause brain damage, MDA is a flat out known neurotoxin...PCP is neurotoxic..lots of drugs are neurotoxic.
 
It really doesn't do a lot of good to get all over someone for asking a simple question, not everyones a drug nerd and the op is making an effort to learn by asking us.


And to answer your question without being a dick, no. The myth started because of MRIs taken before and after ecstasy use, there were a lot of black spots on the after picture. People who have no business interpreting MRIs looked at it and said that ecstasy puts holes in your brain when in reality the MRI was showing depletion of seratonin.
 
jamtastic has the right idea, but meth is FAR from the only neurotoxin.
regular amphetamine if i remember right is neurotoxic in either rat brains or primate brains, but not humans
look up a chem called somehting like 4-chloroamphetamine, neurotoxin used in research to kill dopamine neurons in brains.
most neurotoxins are probably stim type droogs, yes, but i get sick and tired of seeing people insist e is safe when its in reality, pretty fucking far from it. methamphetamine is far more well studied than MDMA, MDMA SURELY is neurotoxic to some degree, MDA is and has been a known neurotoxin for a long time, methamphetamine is neurotoxic, etc.
 
This is actually a really good topic. I know a guy whos forty something and has been doin meth damn near all his life and is completely functional. Has a good job. Always puts his job before drugs. Nicest guy. You can its done some damage cuz he talks A LOT and sometimes to himself but thats about it. My buddy did a lot of X and meth and he was the smartest dealer i ever met. Always remembered if you owed him money or if he owed you. Would do the math for shit right in his head.
 
i mean the thing is, when you look at it, people dont necessarily become "dumber" from meth.
Brain damage from meth? yeah. But i guarantee you MDMA will damage you far worse when abused. and brain damage from meth, id be willing to bet that thats mostly in meth addicts, whove been using for years and years, ya know?
and here is something i think i brought up in one of my other posts.
I am 99% sure MDMA when mixed with substances liek MDA, meth or amphetamine WILL DEFINITELY be neurotoxic, moreso than normally.
I dont see how MDMA WOULDNT be neurotoxic when some of it is metabolized into MDA (and i am sure MDMA has some of the same metabolites as MDA too). MDA is a known neurotoxin, that is how the government was able to emergency schedule MDMA, by saying it is related to a drug that causes brain damage (MDA)
 


Also, its odd to say that meth would cause damage but mdma would, the MA in MDMA stands for Methamphetamine. (3,4-Methylenedioxymethamphetamine. Not saying the poster is wrong/right, just interesting that a supped up form of meth = exctasy.

Lasltly, I believe the problem with mdma revolves around serotonin, I could be completely wrong, but someone please correct me if I am. Actually, I'm almost positive the reason so many think e causes holes is related to serotonin syndrome.



NO IT DOES NOT CAUSE ANY HOLES IN YOUR BRAIN


I'm not saying that MDMA doesnt (can't) cause damage to the brain.. but the fact it has Methamphetamine in the name is irrelevant.. They're 2 different chemicals.. chloroamphetamine is a potent neurotoxin to 5-ht neurones where as amphetamine is not!

Also.. the myth came from oprah (the chat show hosts programme) in which a "scientist" showed a brain scan which appeared to have deep gold ball sized holes in the brain..

It could have also come from the "scientist" that injected monkeys full of meth and concluded that MDMA must do the same.. (brain damage)..
 
And Ive met junkies that really seem brain damaged lol

Using a drug like MDMA occasionally is perfectly fine IF you know what you are doing. These 'junkies' that you met are most likely the people that use it almost daily like morons.

EVERY drug is bad for you if you use it out of habit. Almost NO drug will kill/harm you with only one use, or spaced out safely.
 
^ Dr. George Ricarte or something like that right?

Yes, it was Ricarte. It should be noted that he injected insane amounts of meth into the monkeys as well. It actually is appalling to me that the "ecstasy puts holes in your brain" is still being taught as fact when this is VERY old, VERY inaccurate (and well publicised) information. That's nuts.
 
OP: Peter Jennings did an amazing special called Ecstasy Rising in 2004 that exposed the popular but BOGUS research claiming MDMA caused holes in the brain, 80% reductions in serotonin, and parkinsons- it turned out the research had been done using very high doses methamphetamine, not MDMA.

If you are genuinely interested in the real story, and history behind MDMA, it's worth watching and it's less than an hour: http://www.youtube.com/watch?v=XjvNCijeYlI

I get extremely frustrated hearing the bogus research facts stated constantly, even though it was exposed as bogus years ago on a major news source. MDMA is still referred to as a "killer party drug", though it's results in less deaths than alcohol each year, and most MDMA deaths are not caused by the drug itself, but by things such as water intoxication, (many people are told MDMA is extremely dehydrating, they panic, and start chugging water.) Piperazine results in many deaths, but because piperazine is sold as "ecstasy", many piperazine deaths are just called "ecstasy over-doses".

Schools seem to operate under the concept that if they scare you enough, you won't want to do drugs. The idea that it's OK to bend the truth or outright lie because they want to stop young people from having an interest in drugs is wrong- the more mentors, teachers, and schools lie to students, the less trust and respect they have for them. I remember being told weed resulted in rapes, violent crime and killed brain cells. LOL, we were also told ridiculous things about alcohol as well- meanwhile, I'm freaked out because I'm 9, my dad smokes weed daily, and my mom drank- I was worried that my dad might attack me in a "stoned rage", and that his brain was being eaten up by weed.
 
Misinformation is bad, but humans generally follow the crowd and do as they're told. It's the long process of social indoctrination that is different for every society. There's no right and wrong as those are also social constructs -- only constructive and destructive (entropy). Spreading misinformation is, in some cases (this being one), destructive. It's causing harm rather than making our society stronger. If societies make it (or even if they fall), others will learn from the mistakes and build a better, more stable, more successful society with different positive and negative sanctions. As we saw with alcohol and as we're seeing with marijuana, these mores and taboos are changing in our own society and becoming more and more acceptable. The drug prohibition, especially in the USA, will not last. I'd even go as far as to say that it will end in the lifetime of most of the people here.
 
I have to agree with LSDMDMA&AMP that MDMA is far worse for you dose by dose than Meth amphetamine. Thing is the Methamphetamine life style can turn a whole lot shittier quicker, and people get into routines with using meth much faster than MDMA. How ever strictly speaking of taking JUST 1 dose of MDMA or Meth in a year, the MDMA would have caused more damage to your brain and cognition than the meth. Meth acts more primarily on the dopamine system which is much more resilient than the serotonin system which MDMA primarily works on (much more fragile). Not only that the spike of neurotransmitters MDMA releases at once is greater than methamphetamine, and once most of your serotonin is cleared out in your brain dopamine gets oxidized in the serotonin receptors which should never happens unless administered MDMA. One more thing to add is as you guys know a lot of the e pills' have amphetamine and meth cut into it which drastically increases neurotoxic affects ( as stated increase of dopamine while rolling is bad because they get pushed into the serotonin receptors , a big no no)
 
no it does not. im pretty sure it would be impossible to live with physical holes in ones brain. and he lied because thats what drug teachers do, make shit up. just last week my psych teacher called marijuana a "hallucinogen", and gave us these bs number statistics on drugs (LSD is 10 times more powerful than marijuana, heroin is 100 times more powerful than opium etc.).
 
The pictures are an imaging technique that show inactive areas rather than true holes which neurologists usually call lacuna I think. There was a researcher who posited holes in the brain via ecstasy, by an imaging technique for brain activity in animal research. He had to retract his findings as by mix up he had given ecstasy to the amphetamine group and the other way around.

Probably any powerful psychoactive drug can be bad for brains either by over use or individual susceptibility to problems. A good portion of claims about recreational drugs in journals never gets replicated or has methodological problems. Some research is probably aimed at getting findings that make for good propaganda.

Poor research or propaganda hopefully doesn't get anyone out of a the habit of treating potent drugs with cautions respect.
 
no it does not. im pretty sure it would be impossible to live with physical holes in ones brain. and he lied because thats what drug teachers do, make shit up. just last week my psych teacher called marijuana a "hallucinogen", and gave us these bs number statistics on drugs (LSD is 10 times more powerful than marijuana, heroin is 100 times more powerful than opium etc.).

Marijuana can and is classified as a hallucinogen, but not a very potent one. It depends more on the person though. When I smoke at high doses, I sometimes start to have mild hallucinations. Some people after one toke can start hallucinating
 
You don't hallucinate when you smoke.... acid makes you hallucinate .. you have a better chance seeing something trippy while rolling ..

And anything that you abuse will cause damage to your brain and body. Flash backs are a good example.
 
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