• Trip Reports Moderator: M!$ter-ED

1,4 BDO - New Experience - One hell of a bad experience

Incidentally, OP, after my last bout with anesthesia I got so depressed that I went to see a shrink for the first time in my life. He confirmed that anesthesia can have this effect, and put me on fish oil, lexapro, and an exercise program. I felt better within a few days and by 3 weeks out I felt better than I had in years. The lexapro helps and I still take it, but the biggest factor is my morning bike ride. If I do it, I feel normal to good all day, period. Just some stuff to consider if you still feel shitty.
 
Sir Foxx said:
With all due respect I'm going to have to ask you post some credible sources to back up your statement above. One person a few years ago puts up a review, very biased, non-scientific, no actual studies, just a lot of opinion masquerading as facts. Since then 1,4 BDO has been so unfairly judged and the same wrong "facts" have been repeated since over and over until the lie becomes accepted truth.

The studies show overwhelmingly over and over that 1,4BDO is almost identical to GHB in safety. 1,4BDO is almost 100% converted to GHB in everyone, takes longer in some than others, but it still is the same in the end for everyone. The extra side effects you might be referring to and not everyone experiences this are all related to the conversion in the liver with the same 2 enzyme process that breaks alcohol down. Depending on a persons level of those 2 enzymes before hand, many never experience anything disimlar to GHB itself. If have low levels of those enzymes it will take longer and more passes thru liver to convert all of it to GHB. This is where you will see the sideeffects of dizziness, nausea, etc. The extra strain on the liver that this process produces is negligble if you drink any amount of alcohol regularly to semi reguluary.


That may be enough to turn some off of being able to enjoy 1,4 bdo, but lets stop with the unsubstantiated "toxicity" smears. I'll wait to start posting studies to let anyone else find them for themselves.

Also 1,4 converts to GHB not GBL. And GBL is the most toxic of the 3, based on 40 years of studies. Its only use is to convert before using into GHB.
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I honestly have no idea what exactly are you "arguing" with me about. What I stated doesn't need "credible sources": every time I took 1,4B I felt far more nausea than I have with either GHB and GBL, and it seems almost everyone agrees with me.

I never said that 1,4B is somehow more toxic than GHB (although I wouldn't be surprised if it is).

The physical safety of either is actually irrelevant to my point.

My point is that 1,4B, GHB, or GBL (they are all the same thing as far as the nervous system is concerned) are ALL the most destructively addictive drugs I have ever come across. Even if they are 100% nontoxic, the addiction they have caused and the emotional damage that remains to this day is enough to convince me that you have to be insane to take these drugs willingly.
 
1.4bd is sneakier than ghb and gbl when it comes to dosage..It is also less euphoric and more like an intoxicating drunken feeling..
 
Jamshyd said:
I honestly have no idea what exactly are you "arguing" with me about. What I stated doesn't need "credible sources": every time I took 1,4B I felt far more nausea than I have with either GHB and GBL, and it seems almost everyone agrees with me.

I never said that 1,4B is somehow more toxic than GHB (although I wouldn't be surprised if it is).

The physical safety of either is actually irrelevant to my point.

My point is that 1,4B, GHB, or GBL (they are all the same thing as far as the nervous system is concerned) are ALL the most destructively addictive drugs I have ever come across. Even if they are 100% nontoxic, the addiction they have caused and the emotional damage that remains to this day is enough to convince me that you have to be insane to take these drugs willingly.
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Not arguing with you at all. Just having a discussion. Sorry if I came off that way.
 
hedorah said:
1.4bd is sneakier than ghb and gbl when it comes to dosage..It is also less euphoric and more like an intoxicating drunken feeling..
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I find 1,4 bdo to be very consistent, once you find the sweet spot you've got a reliable amount to base different amounts, either up or down, for different purposes.

GBL is all over the place. I'm aware of the that 1.0ml of GBL is approximate to 1.6 of GHB/1,4BDO but in the past when I experimented with it, the sweet spot changed constantly, making it unreliable in effects.
 
Sir Foxx said:
I find 1,4 bdo to be very consistent, once you find the sweet spot you've got a reliable amount to base different amounts, either up or down, for different purposes.
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I agree with this part. I enjoy doing it, but from what i understand, some of it gets metablolized into eythlene glycol. F-ing scary. . . never noticed any unpleasant effects, but I always feel guilty after dosing.
 
GHB SAVED MY LIFE!

Seriously, I would be homeless, jobless and likely dead had I not found this amazing gift from God!
 
I'm guessing it helped him overcome crippling anxiety and / or depression? Which may have been caused by insomnia?
 
Sorry you had a bad expierence, Ghb Is by far my favorite drug. But I only use on the weekend at clubs and such. I have never tried 1,4, but it sounds Alot like gbl, which is no where near as pleasant as ghb
 
To OP, i may have missed some details, but why did'nt you take gbl? Is it illegal in your country or? I also have a lot of experience with gbl, but i had never any of the mentioned side effects the next day, except slight to medium hangover.

I started using it 8 weeks ago for approx. 6 weeks each day, (its quite seductive when your "medicine bottle" is under your bed ^^) but i stopped taking it 2 weeks ago. I'm not the kind of person that uses drugs outside of the weekend because it just does'nt feel "right" to me, so i was sorta shocked by my own behaviour.

I had no withdrawal symptoms and no urge to take it anymore nor had i felt addicted at any time. But i iust used it for fun, not for dealing with everyday-issues so i guess thats it. Lucky me :D

but nevertheless this drug can easily get the best of you and you'll be using it every day without realising, thats the danger. At least for me.

And sorry for you having a bad time on 1,4-bdo, maybe GBL wouldnt have had this effect on you who knows?
 
The addiction sounds horrific...I'm still interested, though, in how the particular interaction of opioid withdrawal and 1,4 induced rebound stimulation interacted in the OP's experience.
...
And....being naive of GHB-like drugs...how is the euphoria distinct from other GABAnergics?

ebola
 
ebola? said:
And....being naive of GHB-like drugs...how is the euphoria distinct from other GABAnergics?
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It's stimulating and dopaminergic at first and sedating later. From wiki:
Activation of both the GHB receptor and GABA(B) is responsible for the addictive profile of GHB. GHB's effect on dopamine release is biphasic,[20] low concentrations stimulate dopamine release via the GHB receptor.[21] Higher concentrations inhibit dopamine release via GABA(B) receptors as do other GABA(B) agonists such as baclofen and phenibut.[22] After an initial phase of inhibition, dopamine release is then increased via the GHB receptor.
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Quasistoned - thanks for the information re 1,4 BDO, GBL, and what they do in the body. And fr0gman, I agree 100% - it is the best. I took GHB legitimately because my severe case of fibromyalgia (from chronic Lyme), in addition to all of the other lovely symptoms and diseases from Lyme, keep me from sleeping and the typical prescription sleep meds don't really work. The problem is that the FDA about a year ago (around the same time I lost my good insurance) request for approval for fibromyalgia was rejected by the FDA. If I wanted Xyrem (GHB) now, it would cost me around $3000 per month.

Because of this, I was looking into 1,4 BDO because GBL is a 'watched' drug. But I'm confused by the addiction most of you have mentioned, GHB included. Because my only experience has been with GHB, I've found that it's gone from my body the next day. I took it for four years, then off for 6 months, on for another 2.5 years, then the loss of my insurance. I never felt either addiction or dependence. The reason I was off for 6 months was when the prescribing physician left to start his own practice.

The thing that GHB did that was so wonderful was to allow my body to really rest. All of the nerve jumping from neuropathy, and the muscle spasms stopped. My pain was very reduced and I woke up in much less pain than I do when I am not on it. The way it is dosed is that you take the first 1/2 at bedtime and the second 1/2 about 3 hours later. Whenever I woke up to take the 2nd dose I noticed nausea, and if someone woke me up during the 2nd part of the night (after the 2nd dose), I had severe nausea. But no one usually tried to wake me up during this time. My husband's snoring didn't wake me up, nor did the garage door in the early morning (our room is right over the garage). I could position my body so that no nerves would be pinched, and my body would stay that way. And I didn't wake due to overnight withdrawal from my (prescribed) pain medication.

If I had to choose what I think is the best drug, GHB would be the one. But you can only get it from one pharmacy in the U.S., and only if you are rich. I thought about trying 1,4 BDO but after all your experiences, I don't think I want to do this. One of the reasons is it sounds like the side effects, like the severe nausea, are so much worse because there are more 'liver processes' before it becomes GHB. And more than one of you have called it poison and dangerous for your body. Thanks everyone, for your honest input, and thanks to the person who started this thread - it's a huge help.
 
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This is all the more reason to never fuck with this entire class of drugs. It sounds equal to swallowing a random solvent or huffing gas. I did, however meet a chick with pharmaceutical GHB - I would maybe try that once lol.
 
^^in all my Bdo(1.4 butanediol) experience it has been 99% positive...ive had minor stomach pains here and there but nothing else side effect wise..of course any drug taken to extreme will hurt you..i do think ghb/bdo are given a much worse rap than they deserve...i feel much worse and much more toxic after a night of drinking alcohol tahn i do bdo/ghb
 
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