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N&PD Moderators: Skorpio
Naphyrone/O-2482
- Thread starter TheAzo
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fastandbulbous
Bluelight Crew
If the Chinese wanted it to stop, all they'd have to do is have a clampdown like they did regarding ketamine a few years ago. Arrest quite a few people involved, execute the top 2 or 3 involved and it would stop overnight. |Ask a Chinese lab about anything that even looks a bit like an arylcyclohexylamine (the group ketamine & PCP belongs to) and they'll drop it and back away so fast it'll make your head swim. Now apply that fear to all RCs and the production instantly stops
organicshroom
Bluelighter
Looks like Naphyrone has escaped the new prohibition laws for cathinones in England/Scotland. This seems rather contradicting, considering Naphryone may potentially be one of the most carcinogenic amongst the common RC's.
naginnudej
Bluelighter
What is the likelihood such an occurrence actually happening? [assuming that there are not any more remarkably popular RCs that flood the market like meph]
Doesn't seem to far fetched from the way you describe it.hamhurricane
Bluelighter
i wouldn't go that far, after all the 4-MeO-PCP has to come from somewhere, and as far as i can tell the ketamine supply has not been impacted too severely...
where there is a will there is a way, where there are $s&€s there are distributors willing to risk their lives. this has been and always will be the story. obviously the more boutiquey molecules are the first to go, which makes the scene less interesting and more thuggish. any pretext for scientific research is abandoned (and yes this pretext did once exist) and oddities like 2-Me-DMT, aMDiPT, N,N-MiPT, 4-HO-NMT quickly go extinct in favor of bulk MDMA and a few years from now 4MMC.
Have 2-Me-DMT, aMDiPT, 4-HO-NMT, etc. ever actually been widely sold? I've seen a few oddities like the above and other rare substances (5-MeO-TMT) on obviously fake vendor postings that just take a random list from tihkal, but I didn't think any of these had actually been sold.
nuke
Bluelighter
- Joined
- Nov 7, 2004
- Messages
- 4,190
I think really it'll just move on to more isolated and lawless countries, like cocaine production which has been variable in location in South America. Where there's a demand, there's a way, I mean, the US can't even remotely stop the production of poppies in Afghanistan even with a strong military presence.
As far as dangerous RCs go, they have quite a history too, like PCP analogues and opioid analogues. There is always somebody out there who wants to make blood money off of someone with a drug abuse problem who can't say no to something, even if it is dangerous. Unfortunately these often tend to be young people, who often tend to overdose and die. This naphyrone is dangerous on a very different level due to carcinogenicity... And a lot of people may be kicking themselves in 10 years time when they get bladder, thyroid, liver or kidney cancer.
The people behind this will get what's coming to them, one way or another. The US has a nasty habit of expediting criminals from all over the world and charging them.Last edited:
MattPsy
Bluelighter
- Joined
- Jan 15, 2006
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- 1,615
Until, of course, the molecules being ordered look nothing like the 'traditional' RCs...
(this is happening NOW... to a limited extent)Last edited:
I mean its good to have rc-scene, not FDA.
This naphyrone is bullshit, but well there are still people who smoke cigarettes even they know that it causes cancer.
the future does look rather bleak, it is easy for the authorities to identify RC compounds because idiot vendors sell them to idiot users on teh interwebs. idiot users end up in hospital and then the whole house of cards comes falling down, and good compounds will get caught by the fallout.
RC vendors need to grow up and move on from the slash and burn, make a quick buck approach because once something is scheduled it is pretty much gone FOREVER, it will never be unscheduled it is gone.
any major dude
Bluelight Crew
I'm actually amazed there aren't more hospitalizations, etc. I've known a lot of drug users and none have gone to the hospital for an RC. Cocaine on the other hand....
So strange how relatively few hospitalizations causes such a big stir. If only politicians would take usage stats into account before screaming DRUGS WILL RAPE YOUR CHILDREN at the functionally illiterate masses... That type of behavior should be criminalized.
How many deaths are directly attributed to mephedrone? I recall reading about the two most recent ones that basically caused the cathinone ban and those kids were also on methadone and lots of booze, already a potentially lethal combo. There may even have been a benzo involved too, but I can't recall and don't have time to find the article right now.hamhurricane
Bluelighter
^^^
thats because despite all the (legitimate) worry about long term effects from chronic use, there is no question that the acute toxicity of mephedrone is quite low. i have read at least a dozen reports of users consuming 10g/night and in a case report published in the journal of medical toxicology last week one user consumed 200mg p.o. followed by 3.8g IM and survived! as awful as this stuff may be for your heart it does not seem especially good at stopping it from beating.
when i look back at the way it was before im amazed that the scene stayed as psychedelic oriented as it did for as long as it did.
ebola?
Bluelight Crew
How do the potential risks of carcinogenic metabolites from naphyrone compare to, say, JWH-018 or JWH-073? I know that this is all pretty speculative, but this is the place for some of the most learned speculation around...
ebolaopenminded2010
Greenlighter
- Joined
- Apr 24, 2010
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- 1
advice
I would like to say i have also taken many drugs over the years and would like to voice my personal experiances of mephedrone and the new nrg1.
Firstly i would like to point out that mephedrone or (cat or bubbles) as its called localy in my area was initially a fun new drug, to start with it made you chatty, happy, it meant you could drink alot without really getting that drunk! I have used the substance a few times and i find there are a few side affect people should be aware of, you can become very paranoid, anxiety, grumpy, short tempered, get pins and needles in your hands and feet, become spaced out, extreamley dehidrated, loss of appetite, sore sides (LIVER OR KIDNEYS?), sleep depravation and bleeding and blood clots from the vagina in women, i have even seen a person who scratches and itches at their skin so often open wounds develop.
I have nothing against sensible drug use but i can see how mephedrone use can be dangerous to peoples health if over used and abused!
I would say form expieriance in small moderate doses its fun, it can give you a hightened feeling of sexuall arousall in males and females (amazing!), but remember we no nothing scientifically about this substance.
If you do try this always drink plenty of water, eat (even though you will have no appetite) have a cut off point where you stop taking and go to bed, because if you dont you could stay up for days and days on end and your body is not designed for it. (you will start tripping)
As far as NRG1 is conserned it is nothing like mephedrone, it is identical to MDPV and the only feeling you will get is extreme paranoia, anxiety and a very strange spaced feeling (not fun at all) i have personally watched hardened recreational drug user take it and freak out, (its a sure thing if you take it).
Also take very small lines, no more than one centimetre in lenght and two mill in width, because its very strong.
I hope i have shed some light to the un-informed?
and please dont take the piss out of my spelling and grammer, i am just trying to make people aware of the risks, tried and tested on us the sheeple rather than listen to the government controled media who tell us what they want us to know rather than the truth and facts.
indelibleface
Bluelight Crew
But there are many medications on the market that have the "napthyl-" moiety and are not carcinogenic. Just the fact that the drug has a napthylene within its structure does not confirm its carcinogenicity. Is it possible to determine if epoxides or other carcinogenic byproducts could be formed from the structure alone, or is this something only a real pharmacological study could determine?
Well, the reason most of us (i think) are accusing Naphyrone of carcinogenicity is it's similarity to pronethalol, which was found to be carcinogenic.
http://en.wikipedia.org/wiki/Naphyrone
http://en.wikipedia.org/wiki/Pronethalol
Can you provide any examples of medications with a napthyl moiety right next to a ketone or alcohol that aren't carcinogenic?hamhurricane
Bluelighter
^^^
propranolol
indelibleface
Bluelight Crew
I found at least one the other day on Wikipedia; when I get home from work later I will dig it (and others if I remember correctly) up for everyone.
indelibleface
Bluelight Crew
Right, that`s one of many I`m sure. I think there`s something in particular about pronethalol`s structure that allows its napthylene to create an epoxide metabolite.
ebola?
Bluelight Crew
Right. And then, IIRC, there is something in particular about naphyrone's structure (the proximity of the naphyl group to a ketone group) that makes it likely to form such metabolites.
ebola- Status