Am-630

[critical]

Am-630


Chemical Name: 6-Iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-y l](4-methoxyphenyl)methanone'

a active a cannabinoid?

 

[kken]

potent cb2 selective antagonist

 

[critical]

And that means?

potent cb2 selective antagonist

 

[kken]

you cant get high off it

might help generate other receptors, decrease pain, regulates the bonemass and modulates the immunesystem

 

[critical]

A, Ok, to bad then

can u explain this

we found AM630 to behave as an inverse agonist at CB2 receptors but as a partial agonist at CB1 receptors

?

you cant get high off it

might help generate other receptors, decrease pain and modulates the immunesystem

 

[kken]

no its very weak cb1 inverse agonist

 

[critical]

Ok, so it is crap?

I found this, but i don´t understand it?. can someone explain ?


" These results show that WIN 55,212-2 is an agonist and AM630 is an inverse agonist in this system."

no its very weak cb1 inverse agonist

 

[kken]

AM630 has Ki 31.2 nM at CB2 receptors and cb1/cb2 affinity ratio is 165

high dose of AM630 has been noted to antagonise cb1
this is not a chem you should be using for fun. its a tool for reasearching the cb system

ingest some other chem