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"Hard" drug use affecting cannabis high.

I've kind of noticed a similar event myself and was wondering who has felt this, who has NOT felt this (after years of concurrent use) and why it may be true.
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i guess i'm an odd one. ive been taking opiates daily for years and cannabis. pot has ALWAYS been great to me (except the very first time)... it puts me in a realm in my head where everything is positive, not negative as others are saying, things are colorful (with eyes closed :P ) etc. it's an amazing uplifting feeling to have a good weed high. it's a total TRIP like mushrooms

only problem is i cant get high because i smoke every day. gotta stop! but i love weed too much. but when there is no tolerance to weed, and you do it in the right setting, it's an amazing trip... and i guess that's why some people get negative thoughts on weed? my brother says weed gives him negative thoughts. maybe it's the psychedelic aspect, set and setting?

overall, opiates i think caused an increase in my weed smoking, partly because of withdrawal periods (weed is the best for withdrawal) and partly because of their nice synergy of relaxed amazingness. lol... i may sound silly right now, transitioning to subox so i'm in w/d

p.s. i'm prescribed clonazepam 0.5mg x3 daily, perhaps that assists me in my cannabinoid endeavors(sp) and makes it more relaxing. but since ive been taking it so long, i dont really think the klonopin does much anymore
 
My buddy who had been trouble with anxiety on weed sook acid and freaked. Now
hes fine when he smokes weed (like as soon as the trip ended), guess it goes both ways.
 
Weed gives a lot of unpleasant feelings to some peple like paranoia, numbness, feeling retrded and being totally unabe to undego some simple tasks. Cannabis sorts of brings out an unconscious part of you that might turn against you, I get social fobia when being high in public.

To me weed and benzo or even some stims connect just fine.
 
Did weed with amphetamine, and damn it was very nice to meditate. I was like meditating for 2 hours, I zoomed through human evolution and the whole big bang to this day. I could think without words, completely by visualizing it all. Very interesting, need to try it again one day. Nice tool.
 
I recall wed to be much more psychedelic and euphoric when I was a young teen, I had visions of ridiculous images in my mind and heard weird echoing sounds. It used to be delirant then....after my meth years and heavy alcohol partying its becamemore depressing.
Just like ...pffffff....lie my ass down, completely mind numbed and eat some munchies.

I firmly believe that cannabis use affects your brain during development but i cant be bothered to look for papers now.
 
I'd love to have 2 or 3 grams of fresh Kashmir hash, but I don't know if I would get the anxiety symptoms I have nowadays when I smoke (very rarely) cannabis.
 
great thead

As a polydrug abuser and heavy weed smoker I once knew I have believe that once hooked on something more expensive and addictive that is where the money goes.
Pot is expensive, evem more so if you need a gram a day to be happy with all the other drugs one seeks. It takes a backseat and then, I think through the experience of sobriety and becoming clean or cleaning up your attack to have some strand of a life.. here is when and where Pot becomes a problem drug. It brings back memories and is strong to your drug of choice was the last time you used it. It all seems to add up to me.
 
most 'hard' (how ever you classify it) drugs inhibit GABA and glutamate synaptic transmission in Nac (reward section of the brain) and so does cannabis. Drug naive brain (when you started weed) most likely had less dopamine receptors and/or altered synaptic processes as well.


"
these studies suggest that the cannabinoid-induced increase in DA accumulation in the NAc may result from an increase in DA neuron firing and burst rates as a result of CB1 receptor activation. Furthermore, the increased activity of VTA DA neurons caused by the agonist HU210 in brain slices (Cheer et al., 2000)
"

"D-amphetamine in rats that had been administered with WIN 55,212-2 during conditioning. SIGNIFICANCE: A stimulatory effect of WIN 55,212-2 on motor activity was not accompanied by place preference. Upon completion of the CPP procedure, this dose was found to induce region-specific hyperdopaminergia along with a greater sensitivity to a subsequent challenge dose of D-amphetamine (Life Sci., 2009 Jul 31;85(5-6))"

"The cannabinoid CB(1) (CB(1)) and dopamine D(2) (D(2)) receptors are coexpressed in the basal ganglia, an area of the brain involved in such processes as cognition, motor function, and emotional control. Several lines of evidence suggest that CB(1) and D(2) receptors may oligomerize, providing a unique pharmacology in vitro and in vivo

agonist-induced modulation of CB(1)-D(2L) oligomerization may have physiological implications in diseases such as Parkinson's disease and drug abuse"
 
As an opiate user, the high isn't so much intense as it is just unfun - this was before now, back when i was more of a dope addict. I compared weed to being on a roller coaster.

I love my weed, but when you're used to dope, smoking weed just feels more like a crude high - forget euphoria and all that other shit, you'd be lucky if you can get any recreation out of it at all.
 
high quality hash lacks nearly all the anxiety that weed brings me.

smoking pot untill you develop an association betweens weed and anxiety in your mind, does seem to be part of the problem.

still i never had the problem with hash

even now i find high grade hash to be the best drug going
 
pofacedhoe said:
smoking pot untill you develop an association betweens weed and anxiety in your mind, does seem to be part of the problem.
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Agreed.

A lot of it is a mind game--if you want to believe it it will come true. After smoking weed with regularity for almost 2 years I had my first run in with extreme paranoia smoking weed two weeks ago. I tried to shrug it off at first but it kept bothering me. Whenever I would go back I could feel the anxiety before it started.

I made it a point to calm myself before smoking the past few times and I've been fine since.
 
naginnudej said:
Agreed.

A lot of it is a mind game--if you want to believe it it will come true. After smoking weed with regularity for almost 2 years I had my first run in with extreme paranoia smoking weed two weeks ago. I tried to shrug it off at first but it kept bothering me. Whenever I would go back I could feel the anxiety before it started.

I made it a point to calm myself before smoking the past few times and I've been fine since.
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this is true and also when the weed rush hits you lie down for about half an hour and breathe slow and close your eyes and it will become far more mellow after the half hour point (that is half an hour after the peak weed high):)

as for the association thing a friend of mine who had severe cocaine and alcohol/xanax/valium addiction said that weed was the first time he got bad anxiety and then used alcohol to calm it. anyway a year or two ago he flipped out after being up for 2 days on strong speed and strong coke after he had a spliff and ended up in hospital getting an ECG. the key to him flipping was the spliff. hospital said his heart was fine he was having a panic attack
 
As an ex opiate addict I can't touch weed. All it does is precipitate anxiety and very displeasing sensations in my body and torso. It always feels like it fucks with my natural breathing, I start to yawn a lot like I'm not getting enough oxygen.

IDK, but MJ lost its magic for me.
 
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