• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio

Recreational potential of Thymol (an unscheduled highly available propofol analogue)

N0 W4RN1NG

N0 W4RN1NG

Bluelighter
Joined
Jul 16, 2008
Messages
506
Location
Long Island
I posted this in BDD a few months ago, but I didn't really get any answers. I'm hoping that by posting it here maybe someone will be able to hypothesize a little about it. I also took a bit too much d-amp and am putting off a whole lot of projects. =P

N0 W4RN1NG said:
So, Thymol is structurally related to the GABAergic anaesthetic propofol, which has abuse potential. (MJ anybody? :P) THIS link states that Thymol, a component of many plants in the mint family, has GABAergic activity even in the absence of GABA.

Thymol is unscheduled in all countries and can be purchased in bulk online for prices as cheap as $10 a gram. It is, apparently, very widely used in the bee-keeping industry. I won't post a source, but it is very widely available on the internet. It can be smoked and is added in very small quantities to some cigarettes as a flavor enhancer.

Based on this info, I may order like a gram and lace a bit of bud with it and see what happens.

150px-Thymol2.svg.png


^ Thymol.

220px-Propofol.svg.png


^ Propofol.


But first, I was looking for some opinions. Does anyone else think this has any abuse potential?? :?
Click to expand...
 
Thymol is indeed active, but not orally. Where propofol quite potent, thymol is less than half as active.

If you can prepare it for intravenous use, I'd start just slightly on the high side of a propofol dose and work up.

Quick acting, short duration. If it follows propofol, it's going to be especially addictive. That combination is pretty much a winner, though.

Be super careful about combining it with any other sedative though. Even skipping 36 hours of my suboxone, I noticed a much stronger effect than waiting 48 hours after my last dose. (with propofol).

intrarectal administration works, but be really careful.
 
Hammilton said:
...
Click to expand...

Fantastic! Thank you so much, I've literally been thinking about this for months.

I am really not into IV, so one last question, do you have any experience vaporizing Thymol? The fact that it's a cigarrette additive makes me think it might be a viable ROA. I guess intra-rectal would work too failing all else.
 
I've tried 50 mg of thyme oil (which is supposed to be 50%+ thymol) rectally, 50 mg vaporized, 100 mg sublingually and 500 mg orally in liquor, all without any effect. Be careful, especially taking it rectally, since if it turns out to be active and you take way too much you could easily OD. Also, your farts will smell like thyme, so think of an explanation beforehand.

Please let me discourage anyone from attempting injection of thyme oil or thymol - unless you get the miscelle size right you will occlude countless capillaries throughout your body, causing damage to all organs.
 
delic said:
I've tried 50 mg of thyme oil (which is supposed to be 50%+ thymol) rectally, 50 mg vaporized, 100 mg sublingually and 500 mg orally in liquor, all without any effect. Be careful, especially taking it rectally, since if it turns out to be active and you take way too much you could easily OD. Also, your farts will smell like thyme, so think of an explanation beforehand.

Please let me discourage anyone from attempting injection of thyme oil or thymol - unless you get the miscelle size right you will occlude countless capillaries throughout your body, causing damage to all organs.
Click to expand...

Well, I have found a source for crystalline thymol, but still yeah I'd prefer not to IV it. And I;m not sure you can explain something like that away. =D
 
Isn't thymol a liquid at room temp? I got mine mxied up, so I can't really say.

Look at propofol preps to give you ideas

It's very definitely activ,e but poorly available.
 
Hammilton said:
Isn't thymol a liquid at room temp? I got mine mxied up, so I can't really say.

Look at propofol preps to give you ideas

It's very definitely activ,e but poorly available.
Click to expand...


Thanks, will do. But it's a solid at room temp, MP 49C. Plus it's clearly advertised on this website as "Thymol Crystals" haha.
 
I don't know, I had found that thymol-rich herbs (such as Nigella sativa), when crushed and mixed with honey, tend to be very active when one is ill, providing a very instant sense of wellbeing. This preparation is actually very popular in the mid-east and Central Asia as a cure-all.

Also, I once had the above with a bit of K in me, and felt a rush of euphoria. Not sure what that was, didn't get the chance to try it again.
 
I wonder what the methoxylated amphetamine derivative of thymol,3-MeO-p-isopropyl-Amphetamine, would feel like?
 
You can be positive that it won't have any relevance in this thread.

Why? because anyone who bothered to read a single paper on these simple phenol derivatives would know that you alter the phenol and you have no activity.
 
Wouldn't mind trying this just for the novalty value heh.

Any ideas on what dosages would be? I'm thinking a tincture of the stuff could be quite interesting :)
 
The stuff will must stink and the doses needed are probably high. These means you will smell like this stuff for some time....
 
Anyone ever heard of Thymacetin? It's apparently acetylated Thymol, creatively named analogue to the Phenol->Phenacetin convention. The late 19th century was so wild I wish I could've been there. Just grab whatever gets people dead or high, slam an acetyl group onto it and market it as a remedy for flatulence in red haired babies. --> PROFIT!

Seriously though I have this very late 19th century source that makes the following claims:
THYMACETIN (CH3.CO.NH.C6H2[OC2H5].[CH3].[C3H7]). This substance is analogous to phenacetin, inasmuch as the phenol of the latter is substituted by thymol. It is a crystalline white powder, but little soluble in water. In doses of about 7 grains it is credited with hypnotic power. Analgesic properties are also possessed by it. Functional nervous and neuralgic headaches, and mental and other nervous disorders have been successfully treated with it. The dose ranges from 3 to 15 grains. It combines the properties of phenacetin with the antiseptic power of thymol.
Click to expand...

You hear that? Best of both worlds baby! Gets you 9.5 times as high as propofol does while still maintaining the breathe freshening properties of thymol!
 
Last edited:
^Is that referring to oral or parenteral use?

I wouldn't go anywhere near parenteral use of thymol derivatives unless they were part of a proper clinical trial.
a) propofol is a very potent anasthetic I.e not something people can safely self administer
b) it's a complete bitch to formulate (now soya oil) but first formulation was withdrawn and ultimately not even worth considering
c) thymol is not even propofol so dose/safety uncertain

DEFINITELY not one to test parentally.
 
Bitch i AM clinical trial

Or to quote The Great Rizzo of Zoklet:
Well my money is in the bank, and I am ordering 100gs of thymol now. Hopefully the site I'm using has a "fast-as-fuck" shipping option, or else it will probably be a few days before you see me on a thymol binge. I'm going to ingest it in every single manner possible, including just sticking it in my ear. I doubt that will work very well, but what the hell? Let's see just how much "irritation" it brings...Unless I start glowing red and puking up my organs, I doubt very much it will be any more irritating than Mcrjtn.
Click to expand...

no really im not getting near my body with a syringe containing some caustic oil. well maybe near my ass when theres no needle attached, but even that thought makes me cringe lol. thymacetin though DOES sound like it could be win, not in an allround sense, but it might have some application for extraordinary highness and all that. any info on the substance would be much appreciated.
{ignore}
bout time this druggist performs some amateurish attempt at kitchen chemistry with potentially catastrophic outcome again. been a while since i last exploded and come to think of it, ive never even properly been scared shitless of having poisoned myself to death lol.

all im really hoping is something to supply the feeling propofol gave me through whatever route that is convenient. not a big fan of needles tbh (though i did try to smuggle my mainline out by getting dressed in the wake up room today lol. wouldve loved keeping that for a day or two. call a friend with goodies over or go straight for robbing a pharmacy, gun pointed to the pharmacists head, INJECT ME INJECT ME!).

we need back some of that shamanism spirit, less mom/dad attitude! fuck all the this chemical will eat your veins from the inside or itll tickle your vagina so you sneeze. its do or die, get high or get nigh, after all what are we but shamans in the concrete bush equipped with needles to stick up our bodies, our plants are chemical plants and not "living" entities, but in the end we all just wanna get high right?
{/ignore}
oh man im hitting the sack. not gonna skip another night of sleep again anytime soon.
 
Last edited:
You must log in or register to reply here.
Top