Dimethocaine

[theotherside]

For those of us who love coke but haven't seen any good stuff in awhile, I can say that dimethocaine is a good replacement. Like others have said, it didn't give me that initial rush of beautiful energy that real coke does, but what it lacks at the start it makes up for in euphoria. I broke up a half a gram into 5 100mg lines and did one per hour. I maintained a solid euphoria that was like coke, but also not as strong or fiendy. It is a perfect buzz for a work night when you want to feel good but also need to get a few winks. I preferred it to MDPV, although I can say that MDPV is alot stronger.

 

[mafius]

So when dimethocaine is mixed with alcohol, what does it yield?

Dimethoethylene?

 

[Coolio]

Dimethocaine is not structurally similar to cocaine, so why would you think the human liver would be able to create "dimethoethylene"?

 

[dread]

Dimethocaine lacks the methyl ester group of cocaine which would allow for transesterification with ethanol to happen.

 

[mafius]

Dread,

Thanks for the answer.

 

[Hammilton]

Dimethocaine is not structurally similar to cocaine, so why would you think the human liver would be able to create "dimethoethylene"?

it has little to do with close structural similarity. A similar conversion occurs with methylphenidate when consumed with ethanol. Dread has explained this.

 

[Coolio]

Hepatic transesterification of methylphenidate, eh? Thanks.

 

[Nagelfar]

it has little to do with close structural similarity. A similar conversion occurs with methylphenidate when consumed with ethanol. Dread has explained this.

That instance may however be due to structural similarity, although the process of ethanol conversion itself may not be.

 

[Hammilton]

As I recall, a whole load of substances will have similar effects occur. methylphenidate isn't very similar to cocaine.

 

[vecktor]

transesterification in vivo is commonplace

 

[ebola?]

Hepatic transesterification of methylphenidate, eh? Thanks.

In another thread, Reimann-Zeta (the Bluelighter, not the function ) speculated that this process would for some reason be selective for the l-isomer. Any idea of why this might be? The wikipedia entry for ethylphenidate suggests greater selectivity for dopamine than the parent compound, explaining why my friend only likes it combined with alcohol (well, that and his burgeoning alcoholism :/).

ebola

 

[correctly]

any one have reports on side effects or some really good effects?
i just got a gram, hows the burn and drip?

 

[mafius]

If you got a gram, just do it and report your findings here.

 

[hamhurricane]

any thoughts on the oral bioavailability of dimethocaine? i try not to snort anything if possible (sensitive nasal membranes) i prefer to take things orally, especially since dimethocaine has no rush in the first place. also any thoughts on how it may combine with moclobemide with selegiline?

 

[dread]

Very probably inactive orally.

 

[Nagelfar]

any thoughts on the oral bioavailability of dimethocaine? i try not to snort anything if possible (sensitive nasal membranes) i prefer to take things orally, especially since dimethocaine has no rush in the first place. also any thoughts on how it may combine with moclobemide with selegiline?

If the oral BA is poor, plugging. Trust me, people have a knee-jerk reaction to the thought. But go to a pharmacy, get a box of one hundred, 100 unit, syringes, any gauge (say 29 so it sounds like you know what you're talking about, and use the word "insulin syringes" when buying them; just got to the pharmacy at a Walgreens or Walmart or any such place), get pliers and pull the needle off, then pull and twist the whole plastic needle holding part off (it hurts when administered)... back-load the dimethocaine in the syringe (pull plunger out and put the powder in), put the plunger back in and tap the syringe former needle head up so the powder falls against the rubber end of the plunger, and push the plunger up so there's no giant air pockets (but don't mash it in their tight so air can't pass through the powder) then draw up any kind of water, the purer the better though, saline is unnecessary, shake it briefly (lab grade dimethocaine should be fairly hygroscopic), insert the syringe to the hilt, lay on your right side (and a bit forward, with buttocks toward the air) and plush plunger down all the way, wait a few seconds, and viola! Administered a liquid rectal suppository that should hit you nice.

 

[mr_jig_a_low]

dimethocaine para-desamino analogue. What does this mean? whats the difference?

 

[Twigs]

dimethocaine para-desamino analogue. What does this mean? whats the difference?

It means a version of dimethocaine without the "H2N"-group on the benzene ring

^ This group is removed

 

[Hammilton]

YEP - when this started showing up on vendors lists, I started contacting them telling them to stop selling dimethocaine proper and start selling the 4-deaminated analouge, which should have less propensity for hepatotoxicity.

There's a good chance it'll have less cardiotoxicity too.

 

[mr_jig_a_low]

Dimethocaine-para-desamino is supposed to be stronger. Is this true? euphoria/stimulant wise

para-chloro-dimethocaine is that the same thing?

also said that 3,4 dichoro would be the strongest of the dimethocaine and clofenciclan. But you related it to a derivative to pcp. Could you elaborate on that please?

Are any of these substances even available? possible to make?? heard of someone making it??

Im looking for the strongest version dimethocaine euphoria/stim wise.