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Bupe Suboxone/Buprenorphine FAQ and Megathread v.1; 2007 - 2010

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I read a pamphlet that talked about this. They say you may feel the urge to re-dose when it isn't necessary because the Suboxone feels like it's not working. They go on to say that you must avoid these urges because it's just the "addiction talking." The more you reward these urges, the more often you will feel them; the longer you avoid them, the less they will come around.

I'm not saying that it really is lasting more than 8 hours for you guys, I'm just bringing it up for something to think about. Could it be possible that you've rewarded these urges to take more so long that you are constantly feeling them now, requiring more doses, when you really don't need them?
 
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Helluva post CH.

Does anyone feel like taking buprenorphine before bed makes you sleep better/worse?

When i used to take 4-8mg sometimes i would take a dose an hour before bed and i would not want to get up, and when i did, i couldn't keep my eyes open for the life of me.

Once i lowered my dose this pretty much went away but just curious how it affects peoples' sleep.


I was the same way before I tapered to 1-2mg.
Anything above 4mg before bed would knock me the hell out, and I'd usually be very groggy in the mornings. And on days I didn't have to wake up early, it'd make me sleep straight til 1 or 2pm (~12-13 hours total sleep) when usually I only sleep 8hrs maximum per night even without an alarm.
 
I read a pamphlet that talked about this. They say you may feel the urge to re-dose when it isn't necessary because the Suboxone feels like it's not working. They go on to say that you must avoid these urges because it's just the "addiction talking." The more you reward these urges, the more often you will feel them; the longer you avoid them, the less they will come around.

I'm not saying that it really isn't lasting more than 8 hours for you guys, I'm just bringing it up for something to think about. Could it be possible that you've rewarded these urges to take more so long that you are constantly feeling them now, requiring more doses, when you really don't need them?

I have thought about this, however I do have days where I only use 0.25mg twice or three times instead of four times, despite being awake and doing just as much stuff in a day, if not more, than the days I use it four times.

It didn't feel as if the Suboxone wasn't working - it was just that the peak was obviously over. The peak of Suboxone is what helps me to be stimulated, motivated, productive, efficient, etc - and what helps keep my cravings for opiates down.

If I was trying to sublingually dose once a day, I would've continued to get the cravings for heroin I had originally by doing it this way. By dosing more than once a day (but no more than four times a day for a whole 24 hour period, minus sleep), I have had virtually zero cravings for heroin, or any other opiates.

Sometimes, especially at night, if I know I need to wake up early in the morning, I will skip the last dose at night so I can get to sleep a bit easier, too.

I'm at a point now where even if I go 12 hours inbetween doses, I don't feel cravings for heroin. This is a significant step, since I still did when I first started using Suboxone. I think it tends to stem from the fact that I am keeping a more steady level of Suboxone.

Depending on how long a drug's half life is, and how long its duration of effects are, you can draw a curve up, peaking, then down. If you take a drug more frequently, the curves will build up on each other, so you're not starting from 0, you're starting a little higher, until you tend to get a peak level in the body.

Having a peak level of a drug in your body, and maintaining the level of that drug there, is what induces the medicinal efficacy of drugs. You want to keep the drug level in someone at a steady level - this is how drugs work most efficiently.

If you were to take an antibiotic once a day (a typical one you are supposed to take 4 to 6 times a day), there wouldn't be a constant presence of the antibiotic in your body; and consequentially, whatever bacteria are targeted by the antibiotics will actually gain a resistance from the drug you were trying to utilize.

Ideally, if I were sublingually using Suboxone once a day...I would probably end up taking a benzo every evening. I don't want to end up having to take a benzo every evening to stave off the anxiety of coming down, etc. I like taking benzos sparingly, so I think using Suboxone in smaller doses, but more frequently throughout the day, works for me better than it would others.

I understand where you're coming from - some people feel it isn't working so they keep taking more and more. I don't like to use Suboxone that way, and I always wait 3 hours minimum inbetween doses (not sublingual doses ;)). Even if I'm not 100% covered by the first dose, I will still wait a few hours.

Somehow I managed to get to a point in my life where I'm not bothered by mild withdrawal symptoms, and I'm not experiencing any cravings at all. This has made me really happy.

Some mornings when I wake up (i.e. the last time I had MDMA - 100mg, went to the club, met up with friends, had a fucking blast) I don't feel any WD symptoms at all, other than yawns and runny eyes/nose. And, that's not abnormal for me (I would yawn a lot and have runny eyes before I started using) - so I'm pretty sure it's not what you describe. However, it is a very possible reality for some people.
 
Not sure if it's been posted here but I just wanted to add some info I found while looking around the interwebz.

This info from naabt.org info for treatment providers. And yes most of us like to know more than the doctors, which is often the sad reality.

This first pdf has been around here I'm sure but just in case some haven't read it I'm putting it up.
HOW BUPE WORKS:
http://naabt.org/collateral/How_Bupe_Works.pdf
(it might not come up on the first try, but definitely works)

PRECIPITATED WITHDRAWAL GUIDE:
http://naabt.org/documents/NAABT_PrecipWD.pdf
(again, it took me several tries to access this from my bookmarks menu. Definitely works just try until it shows up)


The last one is sort of odd. I placed it here so that people can comment on it. It sort of goes along with my other issues with addiction treated with suboxone being treated as a cash cow for physicians instead of a regular chronic illness.

Physician billing for office based treatment of opioid dependence:
http://www.naabt.org/documents/PhysicianBillingForOffice.pdf

Comments are very very welcome.
 
Question about precipitated withdrawal (suboxone)

So tomorrow I'm starting suboxone. I'm not addicted to heroin anymore, but I've been doing it occasionally. (He's putting me on the subs to help cravings, if anyone's wondering)

However, if I were to do heroin tonight at 1 A.M, then take the suboxone tomorrow (4mg) at 1 P.M, would I be in for some precipitated withdrawal? I'm not physically addicted to heroin again, but I don't know if that plays a role in it or not.
 
You will be fine.

If you are telling the truth that is.

I must say however that you have one crazy doctor to be prescribing a narcotic when you are free from narcotics. Crazy logic, but you will be more than satisfied with the result I am sure.
 
What do you mean by "if you are telling the truth that is"?

And yeah, I know. He's prescribing it for depression and to "suppress cravings"
 
Well, if you are dependent on opiates at all then you should probably wait till your in withdrawal before taking your buprenorphine.

And what ever you do, don't do anything silly tonight. You will still be able to get high after starting your Bup.

And by 'silly' I mean: don't do more than you usually would as this will not be your last fling...

That is one special doctor you have. I think that is the first time I have heard of anyone getting on BMT post discontinuation.
 
I'm not dependent at all. I can go a day without it and yeah the mental cravings are nuts, but I'm not physically dependent on them again (yet :l)
 
I think I am starting to understand why your doctor has taken this route ;)

I hope the buprenorphine gives you your life back, like it has for so many people.

Nab
 
Nah man trust me, about a month ago I was a total junkie, and I'll admit to that. I just went a day yesterday without it, and I didn't get dopesick at all. I just want to make sure I won't get precipitated w/d tomorrow.
 
Are you going to be taking the bupe daily, or just as needed (maybe 2-3 times a week) to suppress cravings when needed? I'd really strongly advise you to not take it daily. Since you're not physically dependent on opiates yet, it would be silly to start taking bupe everyday and developing a dependency on it in order to ward of mental cravings for H.

Unfortunately since everyone responds to drugs differently, I don't think anyone can say for sure if the timeframe you gave of just over a day is sufficient to not go into precipitated withawal. (But if youre not physically dependent, I'm not totally sure you would go throug precipitated w/d anyway, since your mu opioid receptors don't require a certain amount of drug present for you to feel normal). Anyway, 24 hours is probably enough for the heroin to be out of your system, but you may want to take as long as 36 hours to be safe.

I'm not entirely sure why you feel you need something to take away H cravings, unless you have exhausted all non-pharmacological options like exercise, etc., and found them wanting, but I wish you luck nonetheless.
 
just because you went a day without heroin without being in withdrawal, it doesn't mean your not addicted/dependent on the drug anymore, it might mean you are less dependent on it though.

as for the question at hand, 12 hours isn't too long to wait after full agonist dose. you better be right when you say you're not dependent on the heroin, cause if you are, you most likely WILL go into precips. I've known people that waited close to 24 hours and still went into precips, albeit they were dependent on the heroin at the time.

If i were you, i would wait at least 18-20 hours after last heroin dose to do the buprenorphine, just to be safe. there is no need to rush it, even though you are probably desperate to get high. 24+ hours would be even better. personally, i used to wait 17-18 hours after my last heroin shot before i dosed the bupe, and i never had any problems, but that is me. everyone is different. I would always do the heroin soon before bed, so i could sleep the 18 hours away and dose soon after i woke up. that always worked pretty well. cause i know i always hated waiting.
 
Wow, I hadn't checkd back in a while, what an awesome description of what to try!! I will see how aggresive I can do this, because I really want to be off of the subs, but this will help me out a lot, especially with how to prepare my tapering dosesthanks
 
I've been off of Suboxone for 59 hours now and I still can't get high on oxycodone!! This is really pissing me off! What gives guys???????

oh man check this out... Last night i did 300mgs of Oxycodone and didn't even get faded... This was all blocked by suboxone that i had taken yesterday morning/afternoon.. biggest waste of money, and i really pushed suboxones limit which i am sure now are endless.. i could of done 2,000mgs and still been completely normal
 
Let me get this straight...

You took Suboxone yesterday morning, then took Oxycodone last night expecting to get high?

WTF, dude? That wasn't even 24 hours you waited. Did you honestly expect to get high by then? It takes AT LEAST 36 hours to be able to feel full effects from agonists again. You barely waited 12.
 
Pontential for RELAPSE

So... I have noticed over the last 6-10 months of taking Sub that I have days (Sometimes back to back) where it doesn't seem to work as well... Like I'm hung over when I wake up and the cravings are back FULL ON... Now I assume this is just the mental side of my addiction, which I need to get treatment for, but I was wondering if anyone else experiences this? Like REALLY bad days that come from out of nowhere??
 
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