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Dissolving benzos in a lipid before injection

K

kapten

Greenlighter
Joined
Jan 25, 2009
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Apologies if this is the wrong thread, but I didn't want inexperienced users trying this out for themselves.

Several sterile and commercially available lipids are availabe on the market (mainly for steroid users).

Would it be possible to dissolve non water soluble benzos in a mixture of say alcohol and cottonseed oil for injection? I'm assuming only I.M. Injection would be safe due to the risk of contaminating the vein with oil.

Any comments would be greatly appreciated.
 
yeah most benzos have virtually 100% bioavailibilty via p.o......so, why? but as the pros do it, diazepam for injection comes usually in a 40% propylene glycol, 10% alcohol, water mix.....this should work for most benzos...
 
SWIM has previously used alcohol, propylene glycol and some water in those ratios (one only has to look up the ingredients for IM diazepam).

Unfortunately it stings like a bugger, and was hoping adding a lipid might reduce the pain somehow.

Oh Well :(
 
Might it work? Sure. All you need to do to inject anything is to dissolve it in a liquid medium- for most benzos, a lipid will work.

HOWEVER-what are you planning to do regarding all the crap in the pills (binders, fillers) that you DONT want in your shot? If you dont have the knowledge and skill to filter out (and I mean REALLY filter out) all of the crap, you are just begging for infections, abscess or worse.

Im thinking about this right now. Imagine a big fat IM shot containing all sorts of fillers, binders, possible sugars, swimming in a lovely, nutrient rich, bateria growth promoting, lipid bath. Shoot that cocktail into your muscle/under your skin, and I cant imagine a disaster NOT ensuing.
 
Thanks for your input

Unfortunately I was under the impression that a .2 micron wheel filter got rid of these "nasties".:(
 
Perhaps it would. However what I can say for sure, is that no filter, no matter how fine, would filter out "nasties" that were soluble in whatever liquid you are using. If any undesirables in your pills are soluble in lipids, then no amount of filtering will get rid of them. This is why Im saying that unless you really, really have complete knowledge and skill in this area, you would be a fool to attempt this. Additionally, you havent answered the most important question perhaps, which is- Given the near 100% bioavailability of most benzos, what benefit are you seeking from injecting it, that could possibly justify the very real risks?
 
solvent concentration

daddysgone said:
Perhaps it would. However what I can say for sure, is that no filter, no matter how fine, would filter out "nasties" that were soluble in whatever liquid you are using. If any undesirables in your pills are soluble in lipids, then no amount of filtering will get rid of them. This is why Im saying that unless you really, really have complete knowledge and skill in this area, you would be a fool to attempt this. Additionally, you havent answered the most important question perhaps, which is- Given the near 100% bioavailability of most benzos, what benefit are you seeking from injecting it, that could possibly justify the very real risks?
Click to expand...

Question: Roche 10 mg Valium tabs (for instance) are mostly cornstarch ( 31% ), magnesium stearate, lactose ( 10% ) and indigo dye. Wouldn't the diazepam dissolve in far less solvent than the starch & stearate, even after several washings? Don't know much about the dye, but I suppose seperating the lactose from the filtrate would be pretty straightforward? Not really arguing for anything, just curious.
 
A lot of benzos (and even barbiturates) have a delay when used IV anyways , between pushing off and effect. For example, ativan has a ten minute delay...

So if you're using the needle because you're looking for a rush... look elsewhere.

-lenses
 
The only benzos that are worthwhile for intravenous use are already water soluble. Go for midazolam or triazolam.

I used to get diazepam ampoules once upon a time. They were alcohol based, and the only thing you noticed when shooting them was the alcohol rush... the diazepam you pretty much wouldn't even notice. Onset might have been faster, but the effect was same as oral.
 
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