I think this is being thread/ topic is being beaten to death slowly with a stick. No pun intended
I must say that keeping a frog in a CAGE is not the equivalent of a human being housed and given food... its being held captive. LET IT BE FREE

The fact that you see no difference does not mean that there is not one. SPECIFICALLY when you can just go and get some synthetics and call it a day and leave the frogies alone.
I personally believe that KARMA is a very real thing. That said, perhaps we can not PROVE that milking the frogs for venom is causing pain but gaining a psychedelic experience at the expense of another living creature just creeps me out. 8)
Your having a psychedelic experience at the expense of another living creature almost everytime you take acid. Think about how many people get busted for acid... one was probably busted somewhere down the line from whom you bought acid from.. so you basically tripped out at the expense of another human beings freedom.
I mean, everything is just subjective to how negative-of-a-look you have on it. I mean if you really wanted, you could go as far to say that just you sitting on your computer right now is causing harm to creatures. because:
you are on a computer, for a computer to work it needs power, plastic, metal among other things. For internet you need power, glass, other computers, metal, plastic, sattelites.
just those 2 things(computer, internet) being in your life mean that
*You are using power from power plants, probably nuclear or coal.
*You are using plastic, which causes alot of pollution in creation process.
*You are the cause of rockets being sent into space, using tonnes of hydrogen which getting uses lots of power and or mining.
*You need glass for international fiber optics, which to make, just the optics, causes pollution, letalone the actual laying of the cables which uses 1000's of tonnes of petrol among other things.
*you need metal for all these things to be possible, whether its the electronics in your computer or the ships that were used to transport the computer to your country, or the trucks that were used to ship the materials to teh factory. To get this metal you need to mine it, which in itself causes pollution aswell.
I COULD GO ON ALL DAY ABOUT HOW JUST YOU EXISTING IS HURTING THE WORLD AND THUS ITS CREATURES.
So seriously, i find it pretty pathetic that you can just sit there, polluting the earth and killing many birds and fish and other animals, and then tell me squeezing a gland on a frog is wrong. Seriously, WTF.