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In a slight Pickle with some GH-releasers, looking for suggestions

Jabberwocky

Jabberwocky

Frumious Bandersnatch
Joined
Nov 3, 1999
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Hello,

I have a bit of a hypothetical problem I'm trying to solve. Suppose somebody has a vial of GH-releaser (CJC-1295). It is a substance that binds to the pituitary gland and releases GH.

The solution this person has is prepped for injection (SC is normally used with this substance), but the idiot who sent it to him prepared the solution WAY WAY WAY too acidic. The person has attempted a SC injection with some of the solution and very much burned his skin/muscles where he injected, causing pain persisting for 2 weeks. The vial contains 5mg of CJC-1295 (more than a month supply).

What can the person do with it? Can he take it sublingually for diminished (but still effective) results? Can he get the acid out some way?

Doesn't want to inject that stuff again as it is VERY painful burning.
 
Sublingual won't work, CJC-1295 is a polypeptide consisting of 29 amino acids*) and, therefore, won't cross any membrane. That's the reason why injection is the only way to go here.

Which acid was used for adjusting the (wrong) pH? And how much is "WAY WAY WAY too acidic"? Because peptides can hydrolyse upon contact with strong acids. And you (or SWIY or whoever) certainly don't want to inject peptide fragments without known biologocal action. Geeeee!

In general, you could neutralize the acid. Take sodium hydrogen carbonate solution and add CAREFULLY!!!!!!!!

- Murphy

*) ...if I counted correctly.
 
ok thats what I thought (about the sublingual). although I remember some peptides being done something to them (adding a carrier?) and that got them oral bioavailability.

I guess I will try to neutralize the acidity like you suggest. sodium hydrogen carbonate? Whats that? Is pure sodium hydroxide way too strong/and or toxic to use?
 
Yeah, NaOH is too strong for this purpose. One drop too much and you have a WAY WAY WAY too alkaline solution. Using baking soda (thx for 'translation' Monkey Mantra) allows a bigger safety margin.

Good luck and please be careful when injection the stuff...

Murphy
 
^^^ What he said. Baking soda will keep the solution buffered around a near-neutral pH - nothin' you can't handle. The pKa is like 6.10 or something. It can pretty much "neutralize" either an acid or a base and bring it back into line with something more bio-compatible. The pH of blood is like 7.4, for reference, and is itself partially based off a carbonate buffer ;)
 
Test the solution on litmus paper first. Slightly basifying your blood with sodium bicarbonate shouldn't hurt (sodium bicarbonate is used in IV sol'ns to basify blood that is too acidic).
 
Don't use store-bought bicarb, thats likely to be baking powder, which has flour in it.

Don't get me wrong on that, but its PROBABLY not sterile=D

You can buy bicarbonate sans rice flour though in pharmacies.
 
Last edited:
Gaian Planes said:
Doesn't want to inject that stuff again as it is VERY painful burning.
Click to expand...
Send that stuff back to the supplier and demand a refund or a better prep.

If you go spreading bad reports about that all over BL he will get on his knees to have you shut up.%)
 
Limpet_Chicken said:
Don't use store-bought bicarb, thats likely to be baking powder, which has flour in it.

Don't get me wrong on that, but its PROBABLY not sterile=D

You can buy bicarbonate sans rice flour though in pharmacies.
Click to expand...

Baking soda as sold in the grocery story is just pure sodium bicarb, Limpet. Pure, as far as food-grade stuff goes. Baking powder is this whole other thing - it's a mix of sodium bicarb and aluminum phosphate (or cream of tartar) and maybe corn starch, depending on formulation. It allows things to leaven instantly at low temp and then again at high temp. Either way, you might recommend against shooting baking soda, but if it's all been boiled and it's intramuscular and he's already exposing it to bacteria, etc. by pouring the stuff out of the bottle and re-doing the pH (which his buddy already botched and exposed before any of this) it's not gonna make anything *worse*, is it?
 
Bah personally I wouldn't inject that batch anyway!

I was making a bit of a sarcastic joke, as over here some baking soda, is exactly what I said it was, I have a tub of what is labelled baking soda (NOT powder) and it is a mixture of rice flour, cream of tartar etc and bicarb.

The joke being, bad to inject it, as its not sterile, the implication being, nobody in their right mind would IV that in the first place (the baking soda)
 
NA, unfortunately I tried this method but he cut off contact with me :|

maybe I'll send one more letter threatening but then again do I really want to inject whatever stuff he sends me after I threaten him 8o
 
^ lmao just to be clear I was kidding in my post above about threatening anybody :)

anyways this situation doesn't apply to me, it applies to someone who isn't me :)
 
growth hormone is goooooooooood

yum your body just eats that shit up bro

you can crank the weight up on the bar way faster than you could without it.
 
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