Need Help Definitive List of Comfort Meds for Opiate Detox/ log of fent detox.

[TheplugsPLUG]

The money ;-)

??

 

[Allylbenzene]

But then again, the vitamin C im touting seems to have similar reviews.

At this point, I wouldn't judge anyone for whatever method they use to kick this stuff as long as it works.

I reckon most people would dismiss a lot of the things you used, either because they're OTC or not a conventional opioid recovery option...which strangely gives it some reverse-stigma type stigma...

 

[notsmokeymcpot42088]

If I had to guess why some people say SR is useless would probably be because they got ripped off. My experience so far with it has been incredible.

Well damn of all people I never thought you would be shilling this wrecklessly -- at least it is in a new thread and you gunna get proper questions

 

[streaM Freak]

Incredible experience - id like to know more before I assume what he means by incredible.

 

[endlessnameless]

Anyone struggling with opiates, I would highly suggest looking into sr17. It is working extremely well going into day 10 with no fetty.

Im not so much 'struggling with opiates' as I am weaning off a baby dose (30mgs) of Methadone that Ive been on since February and when I get to 0mls I need to minimise the withdrawals. How would I look in to SR17 if I wanted to?

 

[Allylbenzene]

Im not so much 'struggling with opiates' as I am weaning off a baby dose (30mgs) of Methadone that Ive been on since February and when I get to 0mls I need to minimise the withdrawals. How would I look in to SR17 if I wanted to?

If you read the SR-17018 thread there's a few very insightful posts about the issues involved. Your scenario seems relatively straightforward compared to fent or other opioids so the methods you'll see in this thread will be pretty effective. The items mentioned have several advantages over SR-17018, particularly the ability to repair things properly. In comparison SR-17018 just offers a superficial fix whilst leaving many things unaddressed.

 

[4DQSAR]

I feel the moment I KNEW SR17018 was a scam was when people claimed to go from having used nitazenes or potent fentanyl derivatives or most recently potent 4PP derivatives to zero in a couple of weeks.

Because with such potent ligands, tolarance and dependence are mostly mediated by receptor internalization.

Put simply, with high-affinity ligands with long mean receptor-occupany times, at some point the receptors are constantly signalling so provide no useful information and the body simply stops replacing the receptors.

I have some direct knowledge of this as anyone who looks back will know I recount the fact that I've known five chemists who did the same two dumb things. They made highly potent opioids and then broke rule 1.

Of the five two are dead, two are still in jail and the last I gave up talking to because for over a year they were still dealing with AWS because the body had to totally readjust to there being fewer receptors in their brain.

However biased a ligand is, it can't act on receptors that no longer exist.

That's why I've been pragmatic about the crisis involving high-potency ligands and suggested research into the 1c derivative of R-4066 - in essense it's a compound more potent than fentanyl but with a half-life three times that of methadone. I just don't think a person who has played with fire can be cured by running their hands under cold water.

But also I have repeatedly noted that without exception, the opioids widely considered to be the MOST potent all have a potency from around x2-x10 morphine, moderate mean receptor occupanty times and moderate durations of action. Put simply, these seem to be the compounds that balance those two forms of tolerance in a way that means tolarence is quite slow so they remain euphoric. Of course the worst traps of all - but people see a potency value and think 'the bigger the better' when we have evidence showing that not to be the case.

 

[TheplugsPLUG]

Well damn of all people I never thought you would be shilling this wrecklessly -- at least it is in a new thread and you gunna get proper questions

Could it be possible I actually think it could help a lot of people?

 

[TheplugsPLUG]

If this about cold turkeying fent....all other less potent Opies for a while are option(and gradually tapperings)....lyrica is ok...idk nothing about clonidine.never tried. Have been quit cold turkey fent two times...i hope there wouldn't be a third time....ibogaine microdosing helps after acute withdrawl....somehow make balance in Ur brain and also got some mu receptor agonist action.....even small,but present.

I have been using SR17 to get off fent. Which seems to upset a lot of people on here. I am not really sure why people are so quick to call bullshit on my experience?

At this very moment John Hopkins University is doing a pretty in depth study on SR.

 

[notsmokeymcpot42088]

Could it be possible I actually think it could help a lot of people?

Care to address the ppl saying you were doing the same shill shit on reddit and messaged them?

Like 4d said when you got ppl claiming to get off super potent opi's in no time with no w/d's you know it spells scam.

I actually am very interested in the compound and the research from john hopkins (depending) --- but every post you make is just "Buy SR17 -- hey guys SR17". I suppose it would be ad hominem to say your handle is helping your case any....

ps RE john hopkins doing a study on sr-17018 -- you have a top right of the page too!! A regular expert in the field

 

[4DQSAR]

I don't think SR17018 is nothing, but neither is it a miracle cure.

It appears to help MOR to readjust to there no longer being an exogenic compound activating receptors but it's low potency is an issue. It's unreliable pharmokinetics are an issue and while I hope it is ultimately of utility - detoxification is rarely the bigger problem. It's maintaining sobriety that is the hardest issue to resolve.

Being sold the way it is is also an issue because it's a 'mystery powder game'.

Nobody knows what they are being sent and yet again when challanged to provide instrumenal data... it all goes quiet.

 

[notsmokeymcpot42088]

we are sympatico there mainly based on production cost and my severe doubt anyone is acting out of altruism. (severe doubt is an undersell honestly --- since they would be the first vendor of all times *afaik* to act out of alrtruism)

Would I like to try some -- sure --- am I about to play the mystery powder game for something I am yet to be convinced is any better for getting off opi's than suboxone. Really I dont get why with a sufficient amount any opi wouldnt work that has like a 4 hour duration or longer....I don't think SR17018 is nothing, but neither is it a miracle cure.

It appears to help MOR to readjust to there no longer being an exogenic compound activating receptors but it's low potency is an issue. It's unreliable pharmokinetics are an issue and while I hope it is ultimately of utility - detoxification is rarely the bigger problem. It's maintaining sobriety that is the hardest issue to resolve.

 

[TheplugsPLUG]

I don't think SR17018 is nothing, but neither is it a miracle cure.

It appears to help MOR to readjust to there no longer being an exogenic compound activating receptors but it's low potency is an issue. It's unreliable pharmokinetics are an issue and while I hope it is ultimately of utility - detoxification is rarely the bigger problem. It's maintaining sobriety that is the hardest issue to resolve.

Being sold the way it is is also an issue because it's a 'mystery powder game'.

Nobody knows what they are being sent and yet again when challanged to provide instrumenal data... it all goes quiet.

I agree with how its being sold is an issue. At least it is still available at this moment. I purchased from 3 seperate vendors with good online reviews and rotated threw the 3 in case I was sent some bullshit. All 3 seems like the same chemical. Maybe not the exact same strength but close. What is truly crazy to me? Is the amount of people who are actively trying to tell me that my experience with SR17 was all bullshit. I thought these forums I would of found more people who would of been supportive but I guess that is just the case with anything online these days. Anyone who wants to check out what I said and peoples responses I posted it in the new member introductions which probably was the wrong place, shit happens.

How exactly do I provide instrumental data on research chemicals that I got off the internet?

 

[TheplugsPLUG]

Care to address the ppl saying you were doing the same shill shit on reddit and messaged them?

Like 4d said when you got ppl claiming to get off super potent opi's in no time with no w/d's you know it spells scam.

I actually am very interested in the compound and the research from john hopkins (depending) --- but every post you make is just "Buy SR17 -- hey guys SR17". I suppose it would be ad hominem to say your handle is helping your case any....

ps RE john hopkins doing a study on sr-17018 -- you have a top right of the page too!! A regular expert in the field

I posted a story on reddit. But someone on here said I was trying to sell him SR in dm's. Which is completely made up nonsense. Maybe he should post a screenshot of my message that never existed?

Are we both living in reality? I have never told anyone or anywhere to go buy sr. Once again people online making shit up based on a comment from someone other than me.

I do not know what you mean by top right of the page? exit? minimize?

 

[notsmokeymcpot42088]

(The top right of the page mentions the sr-17018 study at john hopkins, depending BL and variables I dont know)

Noone is trying to tell you that your experience is bullshit -- simply it could have been reproduced with any other opioid/ate tapered properly.

If you did not DM ppl trying to sell this shite i apologize and was only going by what was publicly posted.

None the less when someone shows up just to post about how great they DOC is and how its a miracle --- pushback is inevitable.

PS -- You ask for a lab report with your order NMR GC/MS

 

[4DQSAR]

@notsmokeymcpot42088 - I finally 'bit the bullet' to see how much dubious suppliers were charging for (whatever it is they actually sent but is labelled) SR17018 and it is FASCINATING.

To borrow a term from a Bohman Brothers EP 'A Twist For Every Pocket'

I began with someone who evidently went 'all in' naming their shop after the product and frankly, it doesn't look great (even at the prices) They DO provide a CoA... from a company that states it does not provide instrumental data to vendors; oh dear. But it strikes me as a bit odd that they sell 50mg tablets at a pretty hefty premium compared to the powder when I'm also aware of how a few pages I've been sent give very specific taper schedules so what are the pills for?

The NMR identifes the batch not as SR17018 but a positional isomer!!! Specifically the 4,6-dichloro homologue. They do add 'probably Cl is in meta position instead orto (sic) position' as I assume it's PRESUMPTIVE i.e. they are told what the sample is supposed to contain and go from there. I say this not as criticism but simply because with just an NMR, 'blind' analysis is almost impossible. But the structural model is overlaid and each atom numbered... but the peaks aren't marked with the numbers which is really odd.

That's why I always recommend an NMR/GC-MS pair. Still not perfect but real-world cases where absolute configuration is required can be counted on the fingers of one foot.

So onto the usual '4 fingers of trust'

1-Use WHOIS to see if the true owners are identified (they are not)
2-Analyse the website to see how many E-mail addresses are associated with it (1)
3-Read the whole website to see if any other method of contact is available (no)
4-Use a tool to find how the website was created as sometimes XSS occurs (yes)

The first three simply shows that the vendors have set their site up so that nobody can name or locate them which I suppose if fair if you are selling a schedule 1 controlled compound. The fourth isn't intrinsically a problem but obviously if a tool is used by many, many sites, it becomes a target as it may offer a sort of 'master key' for all the sites that use it.

I'm genuinely curious to understand why unsealed bags cannot be returned but sealed bags MAY be 'on a case by case basis'. I sense that may be something to do with a legal requirement but if you open it, test it and it's something else - sorry, we won't accept your return!

But the 50mg tablets which appear to be selling out MAY suggest what primate models and a few reports here on BL both mention. That in sufficient doses, SR17018 produces the typical mild subjective effects of low-potency opioids... While I sense pharmokinetics work against it (slow onset, low potency) , it seems entirely possible that users will buy the pills with the stated goal of getting high. If it's supposed to be entirely safe I can imagine people buying it thinking that while not potent, they can quit whenever they want to (cue psychological addiction). Lest we forget, some people take buprenorphine for fun and it most certainly has a stree price.

Site 2.

Holy s**t they are selling 30mg tablets (in three flavours)! On per-mg basis the price is similar but no pretense is being made of any carefully calculated schedule. These f**kers are quite clearly selling them in the hope people would keep on using them. So a third flavour of 杀猪盘 using the safety paradox. People think it's non-addictive (primate models suggest otherwise) and just start taking that stuff instead.

I've said it before, a business model in which a person only buys a low potency synthetically complex compound ONCE makes no sense. But people taking it every day... THAT makes sense.


Site 3.

I found a web-site under construction which had the structural model of trimetubine with the file-name SR-17018.SVG. Now trimetubine is considered a perpherally acting opioid but it's a coincidence that of the millions of things that could be mistakenly saved as SR17018.SVG, that would be one of them.

The more I look, the more I realize that because the DEA didn't act right away (just like tianeptine and 7-OHM) there was a window in which larger scammers (I note several that also sell kratom) will wade in on the simple basis that money is money.

CONCLUSION

Can I just point out that although it seems to be far safer in cases of acute overdose, SR17018 kills in the same ways as classical opioid specifically respiratory collapse (with cardiovasular collapse also being an issue). So if anyone out there is quietly taking increasingly large doses of SR17018 on the basis that it's 'safe', it isn't.

Side-note

In the UK we had a mini-epidemic of deaths caused by tramadol. For a few years clinicians were more or less told tramadol was a safer alternative to codeine. Now by safe they really meant 'non addictive' because the truth is that tramadol is far more toxic. But people who would take a strip (10) 30mg codeine tablets imagined that a strip (10) 50mg tramadol would be similar. It wasn't. So now UK clinicians have circled back to codeine while those of us who have both direct experience and an education know that dihydrocodine is considered inferior to codeine, lasts for 6 hours rather than 4 and is safer. Hence in nations like Japan where they do their homework, plain codeine is rare, DHC is more common as if nothing else the longer action means the patient is prescribed less so there is less to end up on the street.

With SR17018 I sense we have another tramadol in which the fact it doesn't produce physical dependence as quickly is conflated with it being non-toxic.

If and when SR17018 is used clinically, it may well be a really useful 'last step' in which a person on a low dose of methadone or DHCs might benefit from avoiding AWS but it isn't the miracle some people say it is!

 

[TheplugsPLUG]

(The top right of the page mentions the sr-17018 study at john hopkins, depending BL and variables I dont know)

Noone is trying to tell you that your experience is bullshit -- simply it could have been reproduced with any other opioid/ate tapered properly.

If you did not DM ppl trying to sell this shite i apologize and was only going by what was publicly posted.

None the less when someone shows up just to post about how great they DOC is and how its a miracle --- pushback is inevitable.

PS -- You ask for a lab report with your order NMR GC/MS

My experience could not be replicated with any other opiate, not even close. This stuff is nothing like opiates.

Who was talking about how great their DOC is? I never did. You do not even know my doc. I stand by my statement that sr is a miracle. I am down to one 30mg dose. Honestly I probably didn't even need to take it but I did just in case. I do not think there will be any withdrawals from it.

It is too bad that people on the internet want to pushback on my experience. I thought this community would of been much more supportive but I was wrong.