• BASIC DRUG
    DISCUSSION
    Welcome to Bluelight!
    Posting Rules Bluelight Rules
    Benzo Chart Opioids Chart
    Drug Terms Need Help??
    Drugs 101 Brain & Addiction
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums
  • BDD Moderators: Keif’ Richards

Benzos Upregulate receptors Nootropics

Pirrracetamol said:
Hi all
Is there ANYTHING that upregulates gaba receptors?

Nootropics perhaps?

I'm fucked atm can hardly remember the last week and count on one finger simple mathematics.

Help would be very appreciated

Thank you
Click to expand...
What doses of Benzodiazepines were you taking and for how long?

It's also really important to figure out not only pharmacological factors, but social and personal factors.

Additionally, food, sleep and exercise have a fundamental impact on your mental state.

Other pharmacological impacts are real, but the major impact is actually from the above mentioned ones.
 
I'm not sure if you mean only in the very literal sense of up-regulation of the receptors. If you're just asking about supplements that act upon GABA receptors, perhaps similar to how Benzodiazepines do, that opens up a lot more potential options.

Disclaimer

First off, supplements are the wild west. You know how "heavily regulated" pharmaceuticals are in this country? Do you know how totally dangerous and outright criminal these pharmaceutical makers are? Well, take that and remove a huge portion of the regulations and you're left with the world of dietary supplements.

This does not mean it is impossible to get what you need. It just means you have to put in the appropriate amount of time into research. You need to figure out what you need, then find someone who makes it and then verify that that manufacturer is trustworthy. For instance, you might be looking into Mushroom supplements. These are really popular right now.

Now, I'm no expert whatsoever. I know a little bit, but not wanting to misinform, an example: Mushrooms typically have what is called Mycelium, which in simple terms, is like the root system and then the Fruiting Body, which is the aerial part of the fungus. For some Mushrooms, you want the fruiting body. For some, the Mycelium is really the part you want. For some, a certain ratio of both parts is the pinnacle. You will find that unreliable Mushroom suppliers will sell "Mushrooms" that are actually an unknown admixture of Mycelium and the wood/grain it's grown on.

Paul Stamets is a hugely famous Mycologist with his own line of Mushroom Supplements that are sold everywhere. In the course of my own research, I had to find out that this guy, though reputable as a Mycologist, was basically selling C-/D+ level products. He wasn't scamming people. He likely became the victim of someone using his name then cutting corners. Who knows. The idea is, you need to be able to do research. You do not want to put the time and energy into a supplement regimen when you don't even know if you're consuming the supplement in the first place.

Saffron - This is a totally underestimated substance. I'm saying that not even knowing how much a given reader is estimating it to be. It really is that good in my experience. I was blown away by this stuff. If you take a Benzodiazepine, for instance and that drug is going to release a 4-6 hour burst of effect, I almost felt as if Saffron was taking that same total effect, if you will and extended it to a proportional effect that lasted all day.

For the best results, you need to get the right stuff though. You want to get the STIGMA, not the FLOWER. Cheaper brands will try to sell the flower as it is much, much cheaper then the STIGMA, however, the stigma holds the majority of the beneficial stuff. Great for depression, anxiety etc.

Kava - This stuff is very similar to Benzodiazepines/Alcohol in terms of its effects, though it is much more mild. It does not seem to produce major issues of tolerance, dependence or withdrawal. If good quality Kava is used, it doesn't seem to have any ill health effects either. It's great for relaxing, not necessarily for sleep specifically though.

Valerian, Passionflower, L-Theanine - I encourage you to do your own research. These are all different compounds, though I feel they are fairly related in terms of the effects produced.

Reishi Mushroom - This is very relaxing. It can be taken once or twice per day and i find the effects to be pretty long lasting.

If you're just looking for stuff to relieve stress or give you energy, that's different. There are lots of other options. You mentioned GABA specifically though and this is the stuff that came to mind for me.
 
Leprechaun said:
What doses of Benzodiazepines were you taking and for how long?

It's also really important to figure out not only pharmacological factors, but social and personal factors.

Additionally, food, sleep and exercise have a fundamental impact on your mental state.

Other pharmacological impacts are real, but the major impact is actually from the above mentioned ones.
Click to expand...
I don't know really I've kept a log of all the benzodiazapines I've taken but it's 179 days it would take me forever to type.

Yes my diet is good, sleep very poor, exercise 3 times a week.
 
Pirrracetamol said:
I don't know really I've kept a log of all the benzodiazapines I've taken but it's 179 days it would take me forever to type.
Click to expand...
you've been taking benzos for 179 days straight?

You don't need to list everything but a general idea of which ones and roughly at what amounts might be useful, e.g. if you've been taking 60mg of diazepam a day for 179 days then you're going to need a taper, if it's 20mg a week that's a different ball game, if you're mixing in other GABA drugs then that's going to effect your GABA system more and in different ways.

If you've got poor sleep then taking nootropics to help with sleep will be beneficial (but don't expect nootropics to knock you out like a benzo), but that's different from using them to specifically help to repair your GABA system - again tapering off GABA will help you return to baseline.

if sleeps a big issue there are other things you could consider instead of Benzo's to help.
 
Last edited:
placebonaut said:
you've been taking benzos for 179 days straight?

You don't need to list everything but a general idea of which ones and roughly at what amounts might be useful, e.g. if you've been taking 60mg of diazepam a day for 179 days then you're going to need a taper, if it's 20mg a week that's a different ball game, if you're mixing in other GABA drugs then that's going to effect your GABA system more and in different ways.

If you've got poor sleep then taking nootropics to help with sleep will be beneficial (but don't expect nootropics to knock you out like a benzo), but that's different from using them to specifically help to repair your GABA system - again tapering off GABA will help you return to baseline.

if sleeps a big issue there are other things you could consider instead of Benzo's to help.
Click to expand...
How do I post pictures?
I have all roughly 179 written down.
 
Pirrracetamol said:
How do I post pictures?
I have all roughly 179 written down.
Click to expand...
I just responded to your other post about posting pictures, just host it somewhere and then use the insert image button, you then need to right click on the image, select "copy image link" in firefox (or equivalent for other browsers), and paste that link into the insert image dialogue on the forum.
 
placebonaut said:
I just responded to your other post about posting pictures, just host it somewhere and then use the insert image button, you then need to right click on the image, select "copy image link" in firefox (or equivalent for other browsers), and paste that link into the insert image dialogue on the forum.
Click to expand...
I got the host it bit but there's no insert image button. It comes up with this
20260702_232318.jpg
Server responded with 0 code.
 
Pirrracetamol said:
Hi all
Is there ANYTHING that upregulates gaba receptors?

Nootropics perhaps?

I'm fucked atm can hardly remember the last week and count on one finger simple mathematics.

Help would be very appreciated

Thank you
Click to expand...
You may find the following video helpful. The guy does know what he is talking about.

 
Bleaney said:
You may find the following video helpful. The guy does know what he is talking about.

Click to expand...

this is great, thanks for sharing.

the comments provide a help quick summary

0:00 Introduction

9:33 Chamomile (Apigenin)

12:51 Herbs for sleep. 1. Loose Leaf Chamomile Tea + Supplement 2. Magnolia Bark Powder 3. Lemon Balm Leaf

16:49 Vitamin Deficiencies (see a doctor before supplementing magnesium, b vitamins, vitamin D)

18:10 Assist the Benzo Brain to Control it's Speed to Prevent Overstimulation

23:51 Eat Well and Stay Hydrated

25:50 Neuroplasticity Research - Dr. Dale Bredesen, Dr. Datis Kharrazian

29:30 Three Principles of Treatment

29:57 Principle 1. Eliminate everything that inhibits Neuroplasticity (inflammation/toxins)

30:26 Principle 2. Boost Neuroplasticity. Remedies MUST have neuroprotective affects.

31:02 Principle 3. Assist the brain to control excitation. GABA vs. Glutamate

32:01 In-depth Principle 1 - Very Important - Must cut out inflammatories and toxins

35:59 Eliminate inflammation

37:32 Inflammation source 1. chronic stress/cytokines (counter with deep relaxation brain training) Relax as much and as long as you can.

41:05 Therapy and meditation

42:52 Inflammation source 2. Sinus Infections and any other types of infections (counter by removing dairy, using neti pot, checking for/removing mold in your home)

45:02 Inflammation source 3. Gum and teeth infections. Find experienced dentist. Follow a high fiber, low saturated fat diet. Superfood for gum health: tomatoes. Do not use anti-bacterial mouthwash, drink beets/beetroots. Oral probiotics (make sure it contains Lactobacillus Reuteri, good to have in colon. Example brand hyperbiotics PRO-Dental)

53:36 Inflammation source 4. Throat Infections. Oral anti-bacterials targeted at throat. Gargle salt water. Zinc lozenges. Boost immune system.

54:56 Inflammation source 5. Chest infections. Boost immune system. Decrease cortisol/relax.

57:29 Inflammation source 6. Small intestines. SIBO: Small Intestine Bacterial Overgrowth. Takes 4-6 weeks to eliminate. See a doctor for anti-biotics OR treat with natural herbs. Starve the bacteria then implement a diet super high in fermentable fibers. Eat flavanoids. Regrow good bacteria. Ingest L. Reuteri (mentioned earlier) and L. Rhamnosus.

1:03:00 Other Inflammation sources: Smoking, Vitamin deficiencies, Excess Omega-6 oils

1:03:34 Oxidative stress damage and Nitrosative stress damage. Eat clean diet high in plant based flavanoids.

1:03:55 Inflammation source 7. Visceral Fat. Switch diet to plant-based diet. Lose weight. Lower cholesterol. Reverse insulin resistance. Eat A LOT of plants regardless of cutting out meat. Plants should be the majority of your diet.

1:07:35 Back to Principle 1 Eliminating everything that undermines neuroplasticity. Any remedy you take should have emphasis on being neuroprotective rather than just stimulating. Benzo brain has heightened levels of glutamate activity and lower levels of GABA activity. Counter with Gastrodia, Magnolia Bark, Chamomile.

1:09:20 Vitamin Deficiencies are common in people recovering from benzos. Have your doctor do full blood work to find out which deficiencies you have. Common deficiencies in benzo recovery are vitamin D, magnesium, B vitamins. If you do not supplement properly you could have adverse side affects so make sure you get your blood work done and only treat what needs to be treated.

1:10:22 Neuroprotective Supplements. Zinc, anti-oxidant. Taurine, anti-inflammatory. Really strong neuroplasticity boosting treatments. Try these further down the line in recovery. Approach slowly.

1:14:22 Back to Principle 2. Boost Neuroplasticity. Stimulate increase in BDNF (Brain-Derived Neurotrophic Factor) by taking supplements. Examples: low-dose lithium orotate (not to be confused with the Rx mood stabilizer lithium), Curcumin (found in turmeric), Herbs, 12 portions of Flavanoids via juice/smoothies, intermittent fasting, aerobic exercise, high intensity interval training, sleep, hyperthermia therapy (sauna or steam room). Do all techniques not just one. Recovery requires full lifestyle change.

1:20:25 Wrap up.
Click to expand...
 
Pirrracetamol said:
Yes but how do you do it with imgbb
Click to expand...
1. Upload Image to Imgbb
2. copy URL link of photo
3. paste into bluelight comment
4. hit "post reply"

Edit: Bluelight is a fickle little bitch when it comes to posting images from a phone.
 
Last edited:
I think you're just pasting the image link into the post instead of using the insert image button, your hosting is working fine and I can attached the pic without any problem





IMG-20260702-WA0000.jpg
 
You must log in or register to reply here.
Top