Lysergamides LSD: LAYING DOWN THE RAW 🔮 DEAL

[Didgital]

Is the UV so that you can visually see if you're distributing it evenly? Does the UV degrade the LSD and does this mean you have to work fast, or is it negligible?

Yeah. Even if the L solution doesn't actively glow, against the white background of the blotter it's easier to see the liquid distribution throughout the paper. Definitely always pre prepare everything and work fast and safely. I don't know if it degrades it tbh and I've seen it done w and w/o UV. I've also seen UV used afterwards to examine for hot spots, and I have seen some poorly laid pages in my day as well. I forget the exact concentration typically used. I think it depends on the type of blotter paper being used. A lot of what gets sold as blotter art really isn't meant for laying, but it does work just as well.

Use a clean flat surface that can contain any spills. A lot of people will have a 100 tab square that they use to "Mop up" any wet spots. Fan in the room is recommended but not directly over any drying pages. If you let it dry too long before flipping, the art side of cheaply made blotter pages can get stuck and rip off onto the surface.
If you're working with liquid or breaking down into vials, a little tray of kitty litter or sand so the vials don't tip over is super handy. It also absorbs any overflow keeping your surface uncontaminated. Trust me that's important. I saw someone overfill a vial once and not only did they immediately expose themselves, they ended up exposing themselves days later from the contaminated surface that had not been properly cleaned.

Safety tips:
Wear one set of gloves taped to your skin and another set over them so you can replace the outer pair easily and frequently without contaminating your skin. Be very conscientious of what your fingertips touch and be especially cautious about not getting it on any mucous membrane. Long sleeves, Dust mask and goggles can't hurt but mainly so you don't accidentally touch yourself. If you get exposure on your skin, immediately wash with warm soapy water. Have a dedicated trash bin for contaminated gloves, syringe tips, paper towels etc.

If you get it on your mucous membrane, you should carefully put everything away because you're about to be high.

With basic precautions, care, and planning, it is possible to do this reliably without getting high. It is a bit of an art laying each syringe perfectly, but it's not rocket science and there isn't anything mythological about the process, though I bet some people pray over it...

 

[idle_curiosity]

Is the UV so that you can visually see if you're distributing it evenly? Does the UV degrade the LSD and does this mean you have to work fast, or is it negligible?

Photolytic degradation of lysergamides is a major issue, it's one of the reasons that syntheses are usually carried out in the dark or using red light. UV is particularly damaging. However, a few seconds of a low intensity UV light source is probably not that catastrophic, but it should be kept to a minimum.

 

[M!$TER-ED]

A little off topic @Dr. Trismegistus what is your view about LSD causing schizophrenia/? More specific, what is your view about LSD use/treatment in people diagnosed with schizophrenia or have a previous history of psychosis?

 

[Dr. Trismegistus]

Thank you for asking an actual question

 

[M!$TER-ED]

Thank you for asking an actual question

Ok, now what?

 

[Didgital]

Photolytic degradation of lysergamides is a major issue, it's one of the reasons that syntheses are usually carried out in the dark or using red light. UV is particularly damaging. However, a few seconds of a low intensity UV light source is probably not that catastrophic, but it should be kept to a minimum.

Im not an expert in the area but I believe the red light is critical only during a few steps when there is an especially fragile intermediate in solution.

Once it's LSD as a salt i think its relatively quite stable tho yeah blasting it w uv prolly not greatest idea.

 

[Dr. Trismegistus]

I don’t know what to completely think about it yet In the 20 years I have done acid I have never had it give me any kind of psychotic episode. Psychedelics make responses in behavior . they have effects on neuropsychiatric conditions that are really positive! I was not surprised some psychedelic stuff specifically ppls actions are similar to symptoms observed in the disease that can limit their clinical effectiveness I read a study that showed a loss of synapses in schizophrenia, and the positive effects of psychedelics on neuroplasticity synaptogenesis could be totally helpful for a kind of schizo-therapy they say non-hallucinogenic psychedelic analogs could be more beneficial I haven’t really studied it just read articles at random I do think that the genuine experience of visual perception could shed some light on how the disease works
I have seen some kids loose their shit from eating over 8000 mg of mescaline with acid the first thing I said when I heard it was how????? lol but Iguess they were just being stubborn and had ZERO CLUE of what they were doing so there is an age old question what drives a sane man mad could drive a mad man to sanity. That’s an ancient school of thought with mental illness though

 

[Dr. Trismegistus]

It’s outside of where my scientific knowledge about psychedelics fit to give any kind of insight into how the brain functions when suffering from schizophrenia and how handling a dose of acid would work for them

 

[Cheshire_Kat]

Aqueous solutions of lysergic acid diethylamide (LSD) are extremely sensitive to light in the near-ultraviolet region of the spectrum. This rather efficient photoreaction yields a variety of products which have very low affinity for LSD-binding sites on plasma membranes from Fasciola hepatica. Since this photoreaction may be elicited by normal white fluorescent lighting in the laboratory, it represents a potential source of error in determining the binding affinity of LSD. Utilizing this photoreactivity advantageously, [3H]LSD was used to photolabel membrane proteins. Covalent binding of [3H]LSD was shown to be a function of the duration of illumination and was inhibited by 5-hydroxytryptamine and nonradioactive LSD. Sodium dodecylsulfate (SDS) polyacrylamide gel electrophoresis of [3H]LSD labeled membranes from F. hepatica showed two proteins which were selectively labeled by the photoreactive [3H]LSD. This method of direct photolabeling with non-derivatized [3H]LSD may allow identification of LSD-binding proteins in a variety of systems.

PUBMED article on which type of UV light affects LSD

There are three types of UV light wavelengths, A,B, and C. Near UV (A) wavelength is 300-400nm, the type used in "black light bulbs" and to cure resin. Please note that the article states that the light from regular florescent lighting has enough UVA to affect LSD.

 

[M!$TER-ED]

It’s outside of where my scientific knowledge about psychedelics fit to give any kind of insight into how the brain functions when suffering from schizophrenia and how handling a dose of acid would work for them

My personal take on psychedelics and thought disorders associated with psychosis is for one I know first hand that taking metocin (psilocybin) derivative allowed me to stop taking heavy dose of antidepressants and a month later I stopped taking heavy dose of antipsychotics, Thing about it was I've taken psychiatric medications since 1975 for what was diagnosed as schizophrenia-depressive spectrum disorder. I had no withdrawal symptoms from the antidepressant, however, the withdrawal from the antipsychotic produced a few nights of insomnia.

As far as LSD, I haven't had any since 1970s, unlike psilocybin the general consensus about LSD, even here on BL is based on fear and the old war on drugs narrative from the 70s. Information about LSD and thought disorders and psychosis remains a mystery.

 

[cnnka]

My personal take on psychedelics and thought disorders associated with psychosis is for one I know first hand that taking metocin (psilocybin) derivative allowed me to stop taking heavy dose of antidepressants and a month later I stopped taking heavy dose of antipsychotics, Thing about it was I've taken psychiatric medications since 1975 for what was diagnosed as schizophrenia-depressive spectrum disorder. I had no withdrawal symptoms from the antidepressant, however, the withdrawal from the antipsychotic produced a few nights of insomnia.

As far as LSD, I haven't had any since 1970s, unlike psilocybin the general consensus about LSD, even here on BL is based on fear and the old war on drugs narrative from the 70s. Information about LSD and thought disorders and psychosis remains a mystery.

My best friend back in the day who was pretty rational dude took lsd the papers that had 2 doses into 1 paper Hoffman or something like that. He was very messed up for years after and even today more than 10 years ago he dosent seem the same. The stuff really messed him up and he didn’t even had a bad trip it was a great trip actually as he told me. But he wouldn’t talk about it even 5 years after the trip, he had full flashbacks like he started tripping again.

 

[M!$TER-ED]

My best friend back in the day who was pretty rational dude took lsd the papers that had 2 doses into 1 paper Hoffman or something like that. He was very messed up for years after and even today more than 10 years ago he dosent seem the same. The stuff really messed him up and he didn’t even had a bad trip it was a great trip actually as he told me. But he wouldn’t talk about it even 5 years after the trip, he had full flashbacks like he started tripping again.

Yeah I don't doubt that, no one really knows how psychedelics may effect certain people other users seem to use without consequences. I believe because everyone is different there may be some overriding circumstances in people's DNA or something that may trigger a negative reaction. Weed effects me really bad, in the 70s smoking weed was a social event. I had no clue other people didn't feel the way I did when I smoked. Anyway, I believe weed was a major factor in my psych breakdown, however, I was taking a lot of MDA too. Who knows, anytime someone chooses to use drugs there is a possibility of being harmed in some way.

if I were to come across LSD today I would use very sparingly in micro-doses.

 

[cnnka]

Yeah I don't doubt that, no one really knows how psychedelics may effect certain people other users seem to use without consequences. I believe because everyone is different there may be some overriding circumstances in people's DNA or something that may trigger a negative reaction. Weed effects me really bad, in the 70s smoking weed was a social event. I had no clue other people didn't feel the way I did when I smoked. Anyway, I believe weed was a major factor in my psych breakdown, however, I was taking a lot of MDA too. Who knows, anytime someone chooses to use drugs there is a possibility of being harmed in some way.

if I were to come across LSD today I would use very sparingly in micro-doses.

How has cannabis affected you? If you feel like sharing, I’d genuinely find it interesting to hear.

There are definitely many factors at play with psychedelics, from DNA to set and setting, as well as a person’s mindset, thoughts, and overall perspective on life.

I’ve had very intense experiences with mushrooms. They felt like an emotional rollercoaster, with the strongest trips being both terrifying and beautiful at the same time, if that makes sense. I tried LSD once when I was very young, just half a blotter, and I don’t remember much. From what I recall, I mostly felt sober, just laughing a lot with some mild visuals.

I’ve always liked psychedelics, and I can say I still do, although I don’t use them anymore. There was a period when I abused DMT. The experiences were intense and mostly beautiful, with very few negative ones, but all of them were extremely strange. The real fear didn’t come during a trip, but months later when I was trying to process and understand what had happened. I realized I had gone very far spiritually, but in the wrong direction, not the one I wanted. That realization brought a deep fear inside me when I understood what I had seen and how much I had opened myself up spiritually.

On top of that, the overuse completely destabilized me. I had HPPD for months and felt very intense emotions very easily, even without any clear reason. At that point, I was also a bit worried about my mental health, but over time I recovered. Still, the psychological impact and the effect it had on my beliefs is something I can still feel, even if more distantly now. I consider it a big mistake.

For me, psychedelics are the most interesting and beautiful substances, but after such a deep psychological and spiritual opening, I wouldn’t take them again. To be honest, part of me still wants to, but I’m not afraid for my mental health as much as I am for my spiritual well being and beliefs, if that makes sense.

With mushrooms, I saw some of the most beautiful things I’ve ever experienced in my life, and the truth is I would like to see them again. But some things are unique, they happen only once, and it’s not worth forcing them.

I also believe that weed played a significant role in my case. I was smoking all day from a very young age. I had quite a few bad experiences, but I ignored them. Especially after my intense psychedelic experiences, the negatives increased and the positives decreased. When I was finally able to look at it clearly from a different perspective, I realized it was doing more harm than good, so I stopped.

It also felt like it wasn’t allowing the doors I had opened to fully close. In a way, DMT may have helped me realize that everything I was doing back then was harmful for me, from the substances I was using to the way I was behaving toward other people. It might have been a harsh way to learn, but in the end, some positives did come out of it.

I believe that if I hadn’t abused DMT to that extent, I might still be able to enjoy psychedelics. Based on my experiences and what I’ve researched, DMT doesn’t feel like a simple psychedelic. It has a mystical, almost religious character, and I don’t want to get involved with that. I think other psychedelics might also open similar doors. I’m not sure about LSD. I always found it the most interesting, but I never really had the chance to explore it properly.

Now that I’ve mostly closed the doors I once opened in my mind and soul, even though they never fully close, I don’t want to risk opening them again.

 

[iom]

I do think psychedelics can destabilize some people in certain circumstances, even if it's rare. I wouldn't be surprised if cannabis is actually a lot worse in this regard too. I say this as an enthusiastic user of both.

I've personally experienced a couple of actual flashbacks, after my first tripping experience which was on ayahuasca with a lot of DMT in it. They were pretty mild and didn't cause me to freak out. The "worst" one occurred when I was very sleepy, and after a few minutes of pseudo-tripping, I decided it was a sign that I should just go to bed.

 

[M!$TER-ED]

How has cannabis affected you? If you feel like sharing, I’d genuinely find it interesting to hear.

There are definitely many factors at play with psychedelics, from DNA to set and setting, as well as a person’s mindset, thoughts, and overall perspective on life.

I’ve had very intense experiences with mushrooms. They felt like an emotional rollercoaster, with the strongest trips being both terrifying and beautiful at the same time, if that makes sense. I tried LSD once when I was very young, just half a blotter, and I don’t remember much. From what I recall, I mostly felt sober, just laughing a lot with some mild visuals.

I’ve always liked psychedelics, and I can say I still do, although I don’t use them anymore. There was a period when I abused DMT. The experiences were intense and mostly beautiful, with very few negative ones, but all of them were extremely strange. The real fear didn’t come during a trip, but months later when I was trying to process and understand what had happened. I realized I had gone very far spiritually, but in the wrong direction, not the one I wanted. That realization brought a deep fear inside me when I understood what I had seen and how much I had opened myself up spiritually.

On top of that, the overuse completely destabilized me. I had HPPD for months and felt very intense emotions very easily, even without any clear reason. At that point, I was also a bit worried about my mental health, but over time I recovered. Still, the psychological impact and the effect it had on my beliefs is something I can still feel, even if more distantly now. I consider it a big mistake.

For me, psychedelics are the most interesting and beautiful substances, but after such a deep psychological and spiritual opening, I wouldn’t take them again. To be honest, part of me still wants to, but I’m not afraid for my mental health as much as I am for my spiritual well being and beliefs, if that makes sense.

With mushrooms, I saw some of the most beautiful things I’ve ever experienced in my life, and the truth is I would like to see them again. But some things are unique, they happen only once, and it’s not worth forcing them.

I also believe that weed played a significant role in my case. I was smoking all day from a very young age. I had quite a few bad experiences, but I ignored them. Especially after my intense psychedelic experiences, the negatives increased and the positives decreased. When I was finally able to look at it clearly from a different perspective, I realized it was doing more harm than good, so I stopped.

It also felt like it wasn’t allowing the doors I had opened to fully close. In a way, DMT may have helped me realize that everything I was doing back then was harmful for me, from the substances I was using to the way I was behaving toward other people. It might have been a harsh way to learn, but in the end, some positives did come out of it.

I believe that if I hadn’t abused DMT to that extent, I might still be able to enjoy psychedelics. Based on my experiences and what I’ve researched, DMT doesn’t feel like a simple psychedelic. It has a mystical, almost religious character, and I don’t want to get involved with that. I think other psychedelics might also open similar doors. I’m not sure about LSD. I always found it the most interesting, but I never really had the chance to explore it properly.

Now that I’ve mostly closed the doors I once opened in my mind and soul, even though they never fully close, I don’t want to risk opening them again.

Very interesting and thank you for sharing! Addressing your question about how cannabis affected me I have to go back 50 yrs or so..At first I don't think I got off or perhaps I didn't what to look for. Like I said, it was the 70s, I was a junior in high school when I started using. Music and events surrounding the 70s contributed to the drug and counter culture movement. The media played a big part in it as well in a backlash sort of way. News documentaries depicted hippies doing their thing but in a derogatory way. Psychedelic commercials promoting everything from 7UP to IDK whatever. Sorry got carried away....
At first smoking weed was something you did socially, it wasn't until after using for a while weed became a problem. I stayed with a friend for a day or two who had connections...at the time I wasn't getting high like other people seemed to so my friend set out to make sure I got high. Smoked a lot of weed, and pure THC in tin foil, maybe some hash too, don't remember. Finally when all said and done, we were outside sitting on a bench, he and girlfriend went back to their apartment, I don't his gf was very happy I was there, for some reason I couldn't move or make the decision to do whatever. No doubt I was out of my mind...eventually I managed to return to his apartment but I was locked out. I think I tried to get in, he showed me how earlier. Long story short, I ended up crouching in the bushes outside thinking I was invisible.

After that, I don't recall a timeframe, but eventually smoking weed had very negative effect on me. My mind would take a vacation from reality, not in a good way. comatose is a good explanation. I don't think loosing my mind was attributed to a single drug use, it was an accumulation of many factors that did me in.

A few years ago I got a medical marihuana card, bought a product that had traces of THC in it, I wasn't able to use it even though there was a small amount of THC in it.


May I DM you? curious about your experience with DMT

 

[cnnka]

Very interesting and thank you for sharing! Addressing your question about how cannabis affected me I have to go back 50 yrs or so..At first I don't think I got off or perhaps I didn't what to look for. Like I said, it was the 70s, I was a junior in high school when I started using. Music and events surrounding the 70s contributed to the drug and counter culture movement. The media played a big part in it as well in a backlash sort of way. News documentaries depicted hippies doing their thing but in a derogatory way. Psychedelic commercials promoting everything from 7UP to IDK whatever. Sorry got carried away....
At first smoking weed was something you did socially, it wasn't until after using for a while weed became a problem. I stayed with a friend for a day or two who had connections...at the time I wasn't getting high like other people seemed to so my friend set out to make sure I got high. Smoked a lot of weed, and pure THC in tin foil, maybe some hash too, don't remember. Finally when all said and done, we were outside sitting on a bench, he and girlfriend went back to their apartment, I don't his gf was very happy I was there, for some reason I couldn't move or make the decision to do whatever. No doubt I was out of my mind...eventually I managed to return to his apartment but I was locked out. I think I tried to get in, he showed me how earlier. Long story short, I ended up crouching in the bushes outside thinking I was invisible.

After that, I don't recall a timeframe, but eventually smoking weed had very negative effect on me. My mind would take a vacation from reality, not in a good way. comatose is a good explanation. I don't think loosing my mind was attributed to a single drug use, it was an accumulation of many factors that did me in.

A few years ago I got a medical marihuana card, bought a product that had traces of THC in it, I wasn't able to use it even though there was a small amount of THC in it.


May I DM you? curious about your experience with DMT

Yeah DM me freely whenever you want.